Abstract:The aim of the present study was to determine if normal liver cell kinetics can be evaluated using bromodeoxyuridene (BrdU) as the label. BrdU was injected intraperitoneally into 10 male adult rats, 5 were sacrified after 1 hr, and the remainder after 30 days. The livers were fixed in 70% ethanol, embedded in paraffin and histological slides were prepared.The labelled nuclei were revealed using indirect immunoperoxidase staining and easily counted by light microscopy.One hr after labelling, labelled hepatocyte… Show more
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