In Vivo Applications of Inorganic Nanoparticles

Bear, Joseph C.; Charron, Gaëlle; Fernández-Argüelles, Marı́a Teresa; Massadeh, Salam; McNaughter, Paul D.; Nann, Thomas

doi:10.1007/978-1-4419-6956-9_9

Cited by 9 publications

(7 citation statements)

References 223 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, any nanomaterials may be potentially harmful for the living samples as well. Numerous reports demonstrate bio-safety of lanthanide doped nanoparticles 59,91,92 at both the in vivo and in vitro level. Nevertheless, it is also necessary to establish standardized protocols to determine, in a quantitative way, the toxicity of nanomaterials.…”

Section: Local Bio-chemical Microenvironmentmentioning

confidence: 99%

Standardizing luminescence nanothermometry for biomedical applications

et al. 2020

View full text Add to dashboard Cite

show abstract

Section: Local Bio-chemical Microenvironmentmentioning

confidence: 99%

Standardizing luminescence nanothermometry for biomedical applications

et al. 2020

View full text Add to dashboard Cite

show abstract

“…[31][32][33] The QDs were then shelled by decomposing a mixture of zinc(II) diethyldithiocarbamate and metal dithiocarbamate [M = Cd (1a, 1b), Hg (2a, 2b), Cu(3a)] complexes at 120 ºC for 2 hours in the presence of 1-octadecene, trioctylphosphine and oleylamine. The molar ratios of Zn to metal dithiocarbamates (1)(2)(3) used were: 1-1, 3-1, 7-1 and 15-1 unless stated otherwise.…”

Section: Synthesis and Characterisation Of Qdsmentioning

confidence: 99%

“…[1][2][3][4][5] The vast majority of research has been directed into improving the optical properties of quantum dots by increasing quantum yields (QYs), [6][7][8] photostability, [9,10] increasing the range of optical activity [11][12][13] and eliminating "blinking". [14][15][16] Enhancement of the optical properties and QYs relies on the reduction of surface defects in the QD lattice fringes.…”

mentioning

confidence: 99%

Doping Group IIB Metal Ions into Quantum Dot Shells via the One‐Pot Decomposition of Metal‐Dithiocarbamates

Bear

Hollingsworth

Roffey

et al. 2015

Advanced Optical Materials

Self Cite

View full text Add to dashboard Cite

(2015). Doping group IIB metal ions into quantum dot shells via the one-pot decomposition of metaldithiocarbamates. Advanced Optical Materials. DOI: 10.1002/adom.201400570 Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version. If citing, it is advised that you check and use the publisher's definitive version for pagination, volume/issue, and date of publication details. And where the final published version is provided on the Research Portal, if citing you are again advised to check the publisher's website for any subsequent corrections. General rightsCopyright and moral rights for the publications made accessible in the Research Portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognize and abide by the legal requirements associated with these rights.•Users may download and print one copy of any publication from the Research Portal for the purpose of private study or research.•You may not further distribute the material or use it for any profit-making activity or commercial gain •You may freely distribute the URL identifying the publication in the Research Portal Take down policy If you believe that this document breaches copyright please contact librarypure@kcl.ac.uk providing details, and we will remove access to the work immediately and investigate your claim. Quantum dots were characterised and interrogated using TEM, HRTEM, electron diffraction, ToF-SIMS, XPS, EDS spectroscopy, photoluminescence emission and lifetime spectroscopy and UV/vis spectroscopy.

show abstract

“…Additionally, advances performed in the last years on surface modification and functionalization have given rise to improved colloidal stability in complex media and biological buffers and biocompatibility, while allowing their bonding to recognition elements [21]. In this sense, it is especially relevant the development carried out in the field of synthesis of NPs with interesting optical properties that overcome limitations of traditional organic dyes, including gold nanoparticles (AuNPs), semiconductor QDs gold nanoclusters, silver nanoclusters, rare-earth based NPs, carbon dots or dye-loaded NPs [22].…”

Section: Introductionmentioning

confidence: 99%

Quantum Dot bioconjugates for diagnostic applications

Díaz‐González

Escosura‐Muñiz

Fernández-Argüelles

et al. 2020

Topics in Current Chemistry Collections

View full text Add to dashboard Cite

Quantum Dots (QDs) are a special type of engineered nanomaterials with outstanding optoelectronic properties make them as a very promising alternative to conventional luminescent dyes for biomedical applications, including biomolecule targeting, luminescence imaging as well as in drug delivery.A key parameter to ensure successful biomedical applications of QDs is that the surface of these nanomaterials should be modified with appropriate functional groups to ensure stability in aqueous solutions and conjugated with recognition elements capable to ensure an efficient tagging of the biomolecules of interest.Here, we present a review summarizing most relevant strategies for QDs surface modification and for their conjugation to biomolecules for preparation of nanoplatforms for luminescent biomolecule sensing and imaging-guided targeting. Applications of conjugations of photoluminescent QDs with different biomolecules in both in vitro and in vivo chemical sensing, immunoassays or luminescence imaging are revised. Recent progress in application of functionalized QDs in ultrasensitive detection in bioanalysis, diagnostics and imaging strategies developments are here included. Finally, some key future research goals in the progress of bioconjugation of QDs for diagnosis are identified, including novel synthetic approaches, the need of exhaustive characterization of bioconjugates or the design of signal amplification schemes.

show abstract

In Vivo Applications of Inorganic Nanoparticles

Cited by 9 publications

References 223 publications

Standardizing luminescence nanothermometry for biomedical applications

Standardizing luminescence nanothermometry for biomedical applications

Doping Group IIB Metal Ions into Quantum Dot Shells via the One‐Pot Decomposition of Metal‐Dithiocarbamates

Quantum Dot bioconjugates for diagnostic applications

Contact Info

Product

Resources

About