In vivo anti-radiation activities of the Ulva pertusa polysaccharides and polysaccharide–iron(III) complex

Shi, Jinming; Cheng, Cuilin; Zhao, Haitian; Jing, Jing; Gong, Ning; Lu, Weihong

doi:10.1016/j.ijbiomac.2013.06.001

Cited by 78 publications

(46 citation statements)

References 25 publications

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“…Sulfated polysaccharides (SPs) of green seaweeds, are chemically and physicochemically different from those of land plants [6], and may have special physiological effects on the human body [15]. SPs are associated with the surface of animal cells and are involved in biological activities, such as cell recognition, cell adhesion, and regulation of receptor functions, which are of great interest in medicine [16,17,18,19]. For example, well-known SPs of green seaweeds from Ulva and Enteromorpha , which are called ulvans, and their oligosaccharides, have demonstrated strong antitumor and immune-modulating activities [20,21,22,23,24], antihyperlipidemic activities [25,26], and anticoagulant activities [27,28,29,30].…”

Section: Introductionmentioning

confidence: 99%

Overview on Biological Activities and Molecular Characteristics of Sulfated Polysaccharides from Marine Green Algae in Recent Years

et al. 2014

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Among the three main divisions of marine macroalgae (Chlorophyta, Phaeophyta and Rhodophyta), marine green algae are valuable sources of structurally diverse bioactive compounds and remain largely unexploited in nutraceutical and pharmaceutical areas. Recently, a great deal of interest has been developed to isolate novel sulfated polysaccharides (SPs) from marine green algae because of their numerous health beneficial effects. Green seaweeds are known to synthesize large quantities of SPs and are well established sources of these particularly interesting molecules such as ulvans from Ulva and Enteromorpha, sulfated rhamnans from Monostroma, sulfated arabinogalactans from Codium, sulfated galacotans from Caulerpa, and some special sulfated mannans from different species. These SPs exhibit many beneficial biological activities such as anticoagulant, antiviral, antioxidative, antitumor, immunomodulating, antihyperlipidemic and antihepatotoxic activities. Therefore, marine algae derived SPs have great potential for further development as healthy food and medical products. The present review focuses on SPs derived from marine green algae and presents an overview of the recent progress of determinations of their structural types and biological activities, especially their potential health benefits.

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Section: Introductionmentioning

confidence: 99%

Overview on Biological Activities and Molecular Characteristics of Sulfated Polysaccharides from Marine Green Algae in Recent Years

et al. 2014

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“…Polysaccharides have been found to interact with ionizing radiation by reacting with the ROS produced by the ionization of water and other molecules. The carrageenan present in red algae has been found to undergo structural changes including desulfation and acidification which increase the amount of reducing end groups following γ-ray irradiation (Abad et Anti-radiation activities in mice exposed to electron beam radiation Shi et al (2013) Fucoidan purified from F. vesiculosus…”

Section: Ionizing Radiation-induced Reactive Oxygen Species Generatiomentioning

confidence: 99%

Potential applications of radioprotective phytochemicals from marine algae

Oh¹,

Fernando²,

Jeon³

2016

ALGAE

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The use of ionizing radiation and radioactive elements is becoming increasingly popular with the rapid developments in nuclear technology, radiotherapy, and radio diagnostic methods. However, ionizing radiation can directly or indirectly cause life-threatening complications such as cancer, radiation burns, and impaired immunity. Environmental contamination with radioactive elements and the depletion of ozone layer also contribute to the increased levels of radiation exposure. Radioprotective natural products have particularly received attention for their potential usefulness in counteracting radiation-induced damage because of their reduced toxicity compared with most drugs currently in use. Moreover, radioprotective substances are used as ingredients in cosmetic formulations in order to provide protection against ultraviolet radiation. Over the past few decades, the exploration of marine algae has revealed the presence of radioprotective phytochemicals, such as phlorotannins, polysaccharides, carotenoids and other compounds. With their promising radioprotective effects, marine algae could be a future source for discovering potential radioprotective substances for development as useful in therapeutics.

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“…[28] Characterization of IIC IMO and IIC were characterized with an FTIR spectrophotometer (IRPrestige-21, Shimadz, Japan) within 400 to 4,000 cm −1 by the KBr presseddisk method. DSC was carried on a DSC Instrument (200F3, Netzsch, Germany), and IMO and IIC were measured in the atmosphere of flowing, oxygenfree nitrogen with a scanning rate of 10 • C/min from 20 to 500 • C. XRD of IMO Downloaded by [Central Michigan University] at 21:04 06 October 2015 and IIC were recorded on an X-ray diffractometer (XD-3, Pgeneral, Beijing, China), and the scan was performed under the conditions of 36-kV tube voltage, 20-mA tube current, Cu target, and 2 • /min scanning speed to collect 2 θ data from 10 • to 70 • .…”

Section: Determination Of Iron (Iii) In Iicmentioning

confidence: 99%

Preparation, Characterization, and Antioxidant Activity of an Isomaltooligosaccharide–Iron Complex (IIC)

Mao

Liu

et al. 2015

Journal of Carbohydrate Chemistry

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A novel oligosaccharide-iron (III) complex was prepared under the alkaline condition by mixing ferric chloride solution with isomaltooligosaccharide (IMO) solution. Atomic absorption spectrum showed that the iron content of this oligosaccharide-iron (III) complex was up to 37.14%. The comparisons between IMO and its iron (III) complex characterized by Fourier transform infrared (FTIR), differential scanning calorimetry (DSC), X-ray diffraction analysis (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and size distribution showed that iron chelating altered the structural characteristics of the oligosaccharides. Moreover, the evaluation of antioxidant activity indicated that the abilities of IMO to scavenge hydroxyl and 2,2-diphenyl-1-picryl-hydrazyl (DPPH) free radical and the inhibitory effect against lipid peroxidation were greatly improved after the chelation with iron.

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In vivo anti-radiation activities of the Ulva pertusa polysaccharides and polysaccharide–iron(III) complex

Cited by 78 publications

References 25 publications

Overview on Biological Activities and Molecular Characteristics of Sulfated Polysaccharides from Marine Green Algae in Recent Years

Overview on Biological Activities and Molecular Characteristics of Sulfated Polysaccharides from Marine Green Algae in Recent Years

Potential applications of radioprotective phytochemicals from marine algae

Preparation, Characterization, and Antioxidant Activity of an Isomaltooligosaccharide–Iron Complex (IIC)

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