In vivo and in vitro effects on cholinesterase of blood of Oreochromis mossambicus by copper

Basirun, Ain Aqilah; Ahmad, Siti Aqlima; Sabullah, Mohd Khalizan; Yasid, Nur Adeela; Daud, Hassan Mohd; Khalid, Ariff; Shukor, Mohd Yunus

doi:10.1007/s13205-019-1592-0

Cited by 3 publications

(1 citation statement)

References 34 publications

(35 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Samajdar et al, 2015), and that we find CPF to be strongly toxifying to clownfish blood cells or to their precursors (downregulation of all haemoglobin genes), may suggest that it is blood populations that are the ones damaged the most. In fact, acetylcholinesterase is an important membrane component of red blood cells and erythropoietic cells (Lawson and Barr, 1987;Basirun et al, 2019) and, at least in humans, has been found to be a more sensitive readout of organophosphate exposure than other isoforms (Chen et al, 1999).…”

Section: Systemic Effects Of Cpf On Clownfish Larvaementioning

confidence: 99%

The multi-level effect of chlorpyrifos during clownfish metamorphosis

Reynaud,

Vianello,

Lee

et al. 2024

Preprint

View full text Add to dashboard Cite

Chemical pollution in coastal waters, particularly from agricultural runoff organophosphates, poses a significant threat to marine ecosystems, including coral reefs. Pollutants such as chlorpyrifos (CPF) are widely used in agriculture and have adverse effects on marine life and humans. In this paper, we investigate the impact of CPF on the metamorphosis of a coral reef fish model, the clownfish Amphiprion ocellaris, focusing on the disruption of thyroid hormone (TH) signalling pathways. Our findings reveal that by reducing TH levels, CPF exposure impairs the formation of characteristic white bands in clownfish larvae, indicative of metamorphosis progression. Interestingly these effects can be rescued by TH treatment, establishing a direct causal link between CPF effect and TH disruption. Moreover, transcriptomic analysis elucidates CPF's effects on all components of the TH signalling pathway. Additionally, CPF induces systemic effects on cholesterol and vitamin D metabolism, DNA repair, and immunity, highlighting its broader TH-independent impacts. These results enhance understanding of the intricate interplay between CPF exposure, TH signalling and metamorphosis, emphasising the urgent need for mitigating the detrimental consequences of chemical pollutants on marine ecosystems.

show abstract

Section: Systemic Effects Of Cpf On Clownfish Larvaementioning

confidence: 99%

The multi-level effect of chlorpyrifos during clownfish metamorphosis

Reynaud,

Vianello,

Lee

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

Effects of microplastic combined with Cr(III) on apoptosis and energy pathway of coral endosymbiont

Xiao

Liao

et al. 2023

Environ Sci Pollut Res

View full text Add to dashboard Cite

The combined effect of polyethylene (PE) microplastic and chromium (Cr(III)) was investigated on scleractinian coral Acropora pruinosa (A. pruinosa). The endpoints analyzed in this study included the density of endosymbiont, chlorophyll a + c content, activity of enzymes involved in apoptosis (caspase-1; caspase-3), glycolysis (lactate dehydrogenase, LDH), pentose phosphate pathway (glucose-6-phosphate dehydrogenase, G6PDH) and electron transfer coenzyme (nicotinamide adenine dinucleotide, NAD + /NADH). During the 7-day exposure to PE and Cr(III) stress, the density of endosymbiont and the chlorophyll content were decreased gradually. Caspase-1 and-3 activities were increased in the high concentration Cr(III) exposure group. Furthermore, the LDH and G6PDH activities were decreased signi cantly, and the ratio of NAD + /NADH was decreased signi cantly. In summary, the results showed that PE and Cr(III) stress had inhibited the energy metabolism enzymes of A. pruinosa, and further led to the apoptosis of endosymbiont in coral. In addition, the combination of stressors exposure revealed as the concentration of Cr(III) keep at 10 µg/L, the toxic effects of heavy metals on endosymbiont was temporarily relieved with elevated PE In contrary, coral polyps were kept under the concentration of PE at 5 mg/L and increasing Cr(III), the metabolic activities of corals were seriously disturbed, which was increased the burden of energy consumption. In the short term, the deleterious effects of Cr(III) is more obvious due to it led to the apoptosis of endosymbiont and its irreversible damage. It is the rst time to give insights into the combined effect of microplastic and Cr(III) stress on the apoptosis and energy pathway of coral endosymbiont. The results suggest that microplastic combined with Cr(III)contamination is an important factor affecting apoptosis and energy metabolism of coral A. pruinosa.

show abstract

Combined application of biochemical and chemical parameters in the liver of round goby Neogobius melanostomus (Pallas, 1814) for assessing the quality of water bodies

Sigacheva

Skuratovskaya

2023

Regional Studies in Marine Science

View full text Add to dashboard Cite

In vivo and in vitro effects on cholinesterase of blood of Oreochromis mossambicus by copper

Cited by 3 publications

References 34 publications

The multi-level effect of chlorpyrifos during clownfish metamorphosis

The multi-level effect of chlorpyrifos during clownfish metamorphosis

Effects of microplastic combined with Cr(III) on apoptosis and energy pathway of coral endosymbiont

Combined application of biochemical and chemical parameters in the liver of round goby Neogobius melanostomus (Pallas, 1814) for assessing the quality of water bodies

Contact Info

Product

Resources

About