In vivo analysis of intraventricular fluid dynamics in healthy hearts

Cimino, Sara; Pedrizzetti, Gianni; Tonti, G.; Canali, Emanuele; Petronilli, Valentina; Luca, Laura De; Iacoboni, Carlo; Agati, Luciano

doi:10.1016/j.euromechflu.2012.03.014

Cited by 55 publications

(97 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, investigations have been conducted on normal and abnormal hearts leading to potential hemodynamics-based biomarkers for cardiac health. [12,13,14].…”

Section: Recent Technological Innovations In Imaging Techniques Have mentioning

confidence: 99%

Image-based large-eddy simulation in a realistic left heart

2014

View full text Add to dashboard Cite

show abstract

“…Nevertheless, investigations have been conducted on normal and abnormal hearts leading to potential hemodynamics-based biomarkers for cardiac health. [12,13,14].…”

Section: Recent Technological Innovations In Imaging Techniques Have mentioning

confidence: 99%

Image-based large-eddy simulation in a realistic left heart

2014

View full text Add to dashboard Cite

show abstract

“…(3), although care must be taken in imposing appropriate boundary conditions. 13,25,37 Because Eq. (4) is second order and the average pressure gradient (tri-linear terms) follows from the boundary conditions only.…”

Section: Intraventricular Pressure Gradientsmentioning

confidence: 99%

Left Ventricular Fluid Mechanics: The Long Way from Theoretical Models to Clinical Applications

Pedrizzetti

Domenichini

2014

Ann Biomed Eng

View full text Add to dashboard Cite

Abstract-The flow inside the left ventricle is characterized by the formation of vortices that smoothly accompany blood from the mitral inlet to the aortic outlet. Computational fluid dynamics permitted to shed some light on the fundamental processes involved with vortex motion. More recently, patient-specific numerical simulations are becoming an increasingly feasible tool that can be integrated with the developing imaging technologies. The existing computational methods are reviewed in the perspective of their potential role as a novel aid for advanced clinical analysis. The current results obtained by simulation methods either alone or in combination with medical imaging are summarized. Open problems are highlighted and perspective clinical applications are discussed.

show abstract

“…However, they only give access to velocity components directed towards or away from the ultrasonic beam, while one would want to measure the full 3D flow vectors. Nevertheless, investigations have been conducted on normal and abnormal hearts and interesting potential indicators of cardiac health hemodynamics arose [4,13,16].…”

Section: Introductionmentioning

confidence: 99%

Using Image-based CFD to Investigate the Intracardiac Turbulence

Chnafa¹,

Mendez²,

Moreno

et al. 2015

MS&A

View full text Add to dashboard Cite

A numerical framework designed to compute the blood flow in patientspecific human hearts is presented. The geometry of the heart cavities and associated wall motion are extracted from 4D medical images while the valves of the heart are accounted for thanks to low order geometrical models. The resulting blood flow equations are solved using a fourth-order low-dissipative finite-volume scheme and a mixed Aribtrary Lagrangian-Eulerian / Immersed Boundary framework. On top of retrieving the main fluid flow phenomena commonly observed in the left heart, the methodology allows studying the heart flow dynamics, including the turbulence characteristics and cycle-to-cycle variations.

show abstract

In vivo analysis of intraventricular fluid dynamics in healthy hearts

Cited by 55 publications

References 14 publications

Image-based large-eddy simulation in a realistic left heart

Image-based large-eddy simulation in a realistic left heart

Left Ventricular Fluid Mechanics: The Long Way from Theoretical Models to Clinical Applications

Using Image-based CFD to Investigate the Intracardiac Turbulence

Contact Info

Product

Resources

About