“…Applications of the method have included the use of EBI for body composition analysis (i.e., estimation of fat-free mass and total body water) [4, 5], blood volume pulse and limb blood flow quantification [6, 7], cardiac output and function [8, 9], detection of cardiac events such as aortic valve opening [10], wound healing monitoring [11], and, recently, muscle injury and edema assessment [12–14]. To our knowledge, evaluation of EBI as a tool for quantifying knee joint health following acute knee injuries – which may be more subtle as compared to total knee replacement surgery as previously considered [14] – has not been examined by others in the existing literature. Additionally, these previous approaches were mainly limited to controlled lab settings, using bench-top, wall-powered equipment, which are not applicable in a wearable setting.…”