In Vitro Wear Assessment of the Charit?? Artificial Disc According to ASTM Recommendations

Serhan, Hassan; Dooris, Andrew; Parsons, Matthew L.; Ares, Paul; Gabriel, Stefan

doi:10.1097/01.brs.0000228716.60863.ab

Cited by 37 publications

(35 citation statements)

References 35 publications

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“…The results of these tests have been similar to those observed in other metal-polyethylene articulating devices, with wear rates being within the 2-20 mm 3 /MC range [14][15][16][17]. Although comparisons to other implants are useful, further research needs to be undertaken in order to understand the wear processes within TDR, the tribological conditions that will be specific to TDR and the effect of wear debris upon local spinal tissues, particularly with reference to macrophage activation and osteolysis.…”

Section: Introductionsupporting

confidence: 73%

The effect of anterior–posterior shear load on the wear of ProDisc-L TDR

et al. 2010

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The current wear-testing standard (ISO18192-1) for total disc replacement (TDR) requires only four degrees of freedom (DOF) inputs: axial load, flexionextension, lateral bending and axial rotation. The study aim was to assess the effect of an additional DOF, anterior-posterior (AP) shear on the wear of the ProDisc-L TDR. A 5DOF simulator was used to test ProDisc-L implants under 4DOF and 5DOF conditions. The 4DOF conditions were defined by ISO18192-1 whilst the 5DOF used ISO18192-1 conditions with the addition of an AP load of ?175 and -140 N (anterior and posterior, respectively), extrapolated from in vivo data. The implants were mounted such that the polyethylene insert could be removed for gravimetric measurements. Tests were run using bovine serum (15 g/l protein concentration) as a lubricant for five million cycles (MC), with measurements repeated every 1 MC. The mean wear rate in the 4DOF test was 12.7 ± 2.1 mg/MC compared to 11.6 ± 1.2 mg/MC in the 5DOF test. There were marked differences in the wear scars between 4DOF and 5DOF simulations. With 4DOF, wear scars were centralised on the dome of the insert, whilst 5DOF scars were larger, breaching the anterior rim of the dome causing deformation at the edge. The 4DOF wear test showed similar gravimetric wear rates to previously published ISO-tested TDRs. The addition of AP load was found to have no significant effect on the overall wear rate. However, there were pronounced differences in the respective wear scars, which highlights the need for more research in order to understand the factors that influence wear of TDR.

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Section: Introductionsupporting

confidence: 73%

The effect of anterior–posterior shear load on the wear of ProDisc-L TDR

et al. 2010

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“…Therefore, the functional biological activity values in our study 56 are analogous to, but not directly comparable with, the results reported by Fisher's group 46 . Studies other than our own 6,57 focusing on the characteristics of polyethylene particles in the lumbar spine are, for the most part, limited to an in vitro study by Serhan et al 58 . In their study, particle sizes visualized with an environmental scanning electron microscope ranged from submicrometer to >10 mm; however, the mean particle size (5 mm) was an order of magnitude larger than the mean particle size (0.72 mm) in the current study.…”

Section: Discussionmentioning

confidence: 99%

Severe Impingement of Lumbar Disc Replacements Increases the Functional Biological Activity of Polyethylene Wear Debris

Baxter

MacDonald

Kurtz

et al. 2013

Journal of Bone and Joint Surgery

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“…Initial experimental studies conducted under designer/manufacturer auspices reported that the design had negligible wear propensity [12,23]. Another experimental study, by Nechtow et al [16], showed that the Charité could have either very little wear, or significant wear, depending on the input parameters used.…”

Section: Discussionmentioning

confidence: 99%

“…Laboratory simulator tests and, more recently, computational wear simulations, have therefore been increasingly used to predict the long-term wear behavior of TDRs [5,21,23]. Consensus standards and a guidance document for wear testing of TDRs have been developed by the ISO (18192-1) and ASTM (F2423-05), respectively.…”

Section: Introductionmentioning

confidence: 99%

Preferential superior surface motion in wear simulations of the Charité total disc replacement

et al. 2010

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Laboratory wear simulations of the dual-bearing surface Charité total disc replacement (TDR) are complicated by the non-specificity of the device's center of rotation (CoR). Previous studies have suggested that articulation of the Charité preferentially occurs at the superior-bearing surface, although it is not clear how sensitive this phenomenon is to lubrication conditions or CoR location. In this study, a computational wear model is used to study the articulation kinematics and wear of the Charité TDR. Implant wear was found to be insensitive to the CoR location, although seemingly non-physiologic endplate motion can result. Articulation and wear were biased significantly to the superior-bearing surface, even in the presence of significant perturbations of loading and friction. The computational wear model provides novel insight into the mechanics and wear of the Charité TDR, allowing for better interpretation of in vivo results, and giving useful insight for designing future laboratory physical tests.

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In Vitro Wear Assessment of the Charit?? Artificial Disc According to ASTM Recommendations

Abstract: Under these test conditions, the Charité Artificial Disc produced minimal wear debris. Debris size and morphology tended to be similar to other CoCr-UHMWPE joints. More testing is necessary to evaluate the implants under a spectrum of loading conditions.

Cited by 37 publications

References 35 publications

The effect of anterior–posterior shear load on the wear of ProDisc-L TDR

The effect of anterior–posterior shear load on the wear of ProDisc-L TDR

Severe Impingement of Lumbar Disc Replacements Increases the Functional Biological Activity of Polyethylene Wear Debris

Preferential superior surface motion in wear simulations of the Charité total disc replacement

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