In vitro susceptibilities of Aeromonas hydrophila against new antibiotics

Abstract

The antibiotic susceptibilities of 16 clinical isolates of Aeromonas hydrophila obtained from cancer patients with septicemia were studied. Of the new 1-lactam antibiotics tested, azthreonam and moxalactam were the most active, followed by cefoperazone, cefotaxime, and ceftizoxime. Excellent activity was demonstrated by chloroamphenicol, tetracycline, aminoglycosides, and trimethoprim-sulfamethoxazole. Semisynthetic penicillins had no appreciable activity against this organism.

Biochemical Characteristics, Enterotoxigenicity and Susceptibility to Antimicrobial Agents of Clinical Isolates of Aeromonas Species Encountered in the Western Region of Saudi Arabia

“…are generally self-limiting, but antimicrobial treat-ment may be necessary in serious infections, particularly systemic infection in immunocompromised patients. The antimicrobial susceptibility patterns observed in strains isolated in Saudi Arabia were similar to those reported from Great Britain, Canada and the United States of America (Smith, 1980;Fainstein et al, 1982;Gray, 1984). Most strains were resistant to broad-spectrum penicillins and many were also resistant to cefuroxime and cefoxitin.…”

In vitro susceptibilities of tropical strains of Aeromonas species from Queensland, Australia, to 22 antimicrobial agents

“…schubertii was resistant to trimethoprim and ampicillin, moderately susceptible to tobramycin, and susceptible to all of the other 19 antimicrobial agents tested. The present study has shown that strains from the tropics of Queensland are similar in their susceptibility patterns to Aeromonas strains from the temperate climes of Europe and the United States for the aminoglycosides, the broad-spectrum cephalosporins, the quinolones, the ureidopenicillins, tetracycline, chloramphenicol, aztreonam, cephalothin, and ampicillin (2,4,5,10,14,18). The antibiogram of the single northern Queensland strain ofA.…”

“…Until recently, antimicrobial susceptibility studies of motile aeromonads have been undertaken with isolates simply specified as Aeromonas hydrophila (4,5,14). Because various infective processes and virulence factors correlate with different Aeromonas species, later studies have investigated the antimicrobial susceptibility of each of the three Aeromonas species to assist clinical management (2,10).…”

Antimicrobial susceptibility of Aeromonas species isolated from patients with diarrhea

“…are contradictory (1, 2, 5, 6, 13); nonetheless, some investigators have isolated these microorganisms more frequently from patients with diarrhea than from asymptomatic controls (1,2,6). Earlier studies (1,3,4) have identified Aeromonas isolates as Aeromonas hydrophila collectively. More recent data make a distinction between the three currently recognized Aeromonas species, namely A. caviae, A. hydrophila and A. sobria (9,11,13 (4,9,12).…”