In Vitro Study on Effect of Zinc Oxide Nanoparticles on the Biological Activities of Croton tiglium L. Seeds Extracts

Abstract

Croton tiglium L. is categorized as the second largest genus under the Family "Euphorbiaceae". Approximately 1300 species of largely trees, shrubs and herbs that grow under varied environmental conditions in tropical and sub-tropical regions were belonged to this large genus (Torres et al., 2008). Due to the presence of essential oils, the leaves, seeds, stem, roots, and the juice from the bark were widely utilized for medicinal and nutritional purposes among different global communities (Harkat-Madouri et al., 2015;Sai Prassana and Karpaga, 2015). Hu et al., (2010) emphasized that C. tiglium L. seeds are rich in phorbol esters, crotonic acid and fatty acids in addition to active phytoconstituents that are responsible for severe purgative effect of the C. tiglium L. seeds extract. Due to the strong toxic effect of the chemical synthetic products,