In Vitro Multi-Species Oral Biofilms Grown in Presence of H2O2 Production-Affecting Substrates Show Health-Associated Alterations in Composition, Metabolism and Virulence.
Abstract:Modulation of the commensal oral microbiota is a promising preventive or therapeutic strategy for oral health and can for instance be achieved by increasing the abundance and/or activity of certain species. This study evaluated whether 10 selected substrates could modulate in vitro multi-species oral biofilms towards a more health-associated state. These substrates were chosen based on the possibility that they could stimulate H2O2 production by certain commensal species and/or increase their abundance, as pre… Show more
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