In-vitro mineralization of bio-coated 3D printed metallic implant under simulated body conditions

Singh, Gurmohan; Saini, Abhineet; Pabla, B. S.

doi:10.1016/j.matpr.2021.09.321

Cited by 2 publications

(1 citation statement)

References 34 publications

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“…Singh et al reported in vitro mineralization based on 3D-printed Ti6Al4V alloy samples. Their titanium alloy implants were Hap-coated and further doped with strontium and silver nitrate for improved bioactivity and antimicrobial properties, demonstrating that Hap is an ideal biofunctional coating for titanium-based implants . Lett et al utilized the bioceramic properties of Hap and the antibacterial properties of Ag to incorporate Ag+ ions into HAp crystals to form Ag-HAp and used PVA (poly(vinyl alcohol)) for further PLA (polylactic acid) scaffolds.…”

Section: Postprocessing For Printing Objectsmentioning

confidence: 99%

Additive Manufacturing in Orthopedics: A Review

Zhao

Wang

Zhao

et al. 2022

ACS Biomater. Sci. Eng.

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Additive manufacturing is an advanced manufacturing manner that seems like the industrial revolution. It has the inborn benefit of producing complex formations, which are distinct from traditional machining technology. Its manufacturing strategy is flexible, including a wide range of materials, and its manufacturing cycle is short. Additive manufacturing techniques are progressively used in bone research and orthopedic operation as more innovative materials are developed. This Review lists the recent research results, analyzes the strengths and weaknesses of diverse three-dimensional printing strategies in orthopedics, and sums up the use of varying 3D printing strategies in surgical guides, surgical implants, surgical predictive models, and bone tissue engineering. Moreover, various postprocessing methods for additive manufacturing for orthopedics are described.

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Section: Postprocessing For Printing Objectsmentioning

confidence: 99%

Additive Manufacturing in Orthopedics: A Review

Zhao

Wang

Zhao

et al. 2022

ACS Biomater. Sci. Eng.

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Development and evaluation of hydroxytite-based anti-microbial surface coatings on polydopamine-treated porous 3D-printed Ti6Al4V alloys for overall biofunctionality

Singh

Saini

Pabla

2022

Proceedings of the Institution of Mechanical Engineers, Part E:

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The current investigation aims to develop hydroxyapatite-based biofunctional composite coatings on polydopamine-treated porous 3D-printed Ti6Al4V alloy implant specimens for orthopedic uses. The porous 3D-printed implants based on Ashby Gibson’s mathematical model for cellular materials are fabricated at a 65% level of porosity, so as to attain the mechanical strength of human bones. Further, the addition of strontium and silver in hydroxyapatite for improved biocompatibility of the 3D-printed implant to enhance its biofunctionality and its validation is performed. The resulting coated substrates are subjected to a series of morphological, elemental, phase, mechanical, and biological tests. When subjected to the uniaxial compression, the values for modulus of elasticity and yield strength of 3D-printed substrates are compared to the targeted value of elastic modulus and yield strength for the human bones (10–30 GPa and 148–240 MPa, respectively). The effect of polydopamine-treated 3D-printed Ti6Al4V substrates on the coating compositions of calcium and phosphorus has been compared to the untreated samples. The coating thickness and adhesion strength have been calculated and compared for different coating groups. All the samples, except untreated pure hydroxyapatite samples, displayed antimicrobial activity for both the gram-positive and gram-negative bacteria in the zone inhibition test. Hence, the current experiment provides a novel option to fabricate porous Ti6Al4V scaffolds, with a low-temperature surface coating to attain improved biofunctionality for orthopedic applications.

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In-vitro mineralization of bio-coated 3D printed metallic implant under simulated body conditions

Cited by 2 publications

References 34 publications

Additive Manufacturing in Orthopedics: A Review

Additive Manufacturing in Orthopedics: A Review

Development and evaluation of hydroxytite-based anti-microbial surface coatings on polydopamine-treated porous 3D-printed Ti6Al4V alloys for overall biofunctionality

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