In Vitro Investigation of the Antibacterial Activity of Nigella sativa Oil on Some of the Most Commonly Isolated Bacteria in Otitis Media and Externa

Koçoğlu, Esra; Mt, Kalcıoğlu; Uzun, Lokman; Zengin, Ferhat; Çelik, Serdal; Şerifler, Serkan; Gulbay, H; Gönüllü, Nevriye

doi:10.5152/eurasianjmed.2019.18386

Cited by 6 publications

(5 citation statements)

References 19 publications

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“…Nigella sativa oil has an immune response to A. hydrophila in A. testudineus (Khatun et al, 2015). However, Nigella sativa was not effective against P.aeruginosaat any concentration (Kocoglu et al, 2019) and the effect of N. sativa is variable and counts on species of studied microorganisms (Forouzanfar et al, 2014), which may explain the kidney and gill exception in our finding after P. fluorescens infection (IIC) of effect NSO on IL-1β expression.…”

Section: Discussionmentioning

confidence: 66%

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Therapeutic effect of Nigella sativa oil and ciprofloxacin against bacterial infection based on interleukin 1β expression and kidney histopathological alterations in Oreochromis niloticus

Hal

El‐Barbary

2021

Aquaculture Research

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The study evaluated the effect of Nigella sativa oil (NSO) and ciprofloxacin (CFX) on Oreochromis niloticus infected with Aeromonas hydrophila and Pseudomonas fluorescens through kidney function, histopathological changes of kidney and relative expression of interleukin 1β (IL‐1β) in fish organs. The studied fish were divided into four groups based on supplemented diets; each group was divided into three subgroups based on the type of the infection. The results showed increased levels of urea in all infected A. hydrophila and P. fluorescens groups while serum creatinine levels decreased in treated infected subgroups compared to controls. NSO and CFX treatments led to less histological damages in the kidney of infected groups despite the derangement of serum urea and creatinine levels. The up‐regulation of IL‐1β expression was varied based on the type of bacterial infection. After the bacterial infection, NSO led to down‐regulation of IL‐1β expression except in the kidney and gill in P. fluorescens infected subgroups while CFX led to up‐regulation of IL‐1β expression in most studied organs. A positive correlation was observed between serum urea levels and IL‐1β expression levels in the kidney, gill and liver while a negative correlation was observed between serum creatinine values and IL‐1β expression levels in the kidney and muscle. All the studied treatment modalities are effective in augmenting immune response and control of infections.

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Section: Discussionmentioning

confidence: 66%

“…However, Nigella sativa was not effective against P . aeruginosa at any concentration (Kocoglu et al, 2019) and the effect of N . sativa is variable and counts on species of studied microorganisms (Forouzanfar et al, 2014), which may explain the kidney and gill exception in our finding after P .…”

Section: Discussionmentioning

confidence: 99%

Therapeutic effect of Nigella sativa oil and ciprofloxacin against bacterial infection based on interleukin 1β expression and kidney histopathological alterations in Oreochromis niloticus

Hal

El‐Barbary

2021

Aquaculture Research

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“…Gentamicin (10 μg/mL) was used as a positive. Zone diameters were measured after 24 hours of incubation [20][21][22][23][24] .…”

Section: Kirby Bauer Disc Diffusion Methodsmentioning

confidence: 99%

“…The last well without growth was determined as the Minimum Inhibition Concentration (MIC) value. The antibacterial effect of plant extracts was tested by minimum inhibitor concentrations (MIC) against ten control bacterial strains Gentamicin was used to control the study [20][21][22][23][24] .…”

Section: Antibacterial Activity Tests 241 Determination Of the Minimu...mentioning

confidence: 99%

Determination of Antibacterial Activity of St. John's Wort (Hypericum perforatum L.) Oil, Nigella Sativa Oil, Clove (Eugenia caryophyllata) Oil, Orange Peel (Citrus sinensis) and Garlic (Allium sativa) Oil Against Microorganisms Isolated From Clinical Samples

Çelebi

BAŞER>

Güler

et al. 2023

New Trends in Medicine Sciences

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Objective: The aim of this study is to detect St. John's Wort, Nigella sativa, Clove, Orange Peel and Garlic oil on bacteria isolated from blood culture to determine its antibacterial effect. Methods: One hundered blood samples sent to … Medical Microbiology Laboratory between 1 June 2021 and 1 January 2022 were analyzed with blood culture system. Bacteria isolated from blood culture were passaged into blood agar. Bacterial suspension was prepared from the bacterial colonies at 0.5 Mc Farland turbidity. In order to determine the antibacterial activity of plant extract oils, Minimum Inhibition Concentration and Minimal Bactericidal Concentration values were determined by liquid microdilution method. Also, the zone diameters of the disc diffusion method were measured. Results: The antibacterial effect of plant extract oils was detected on only 10 of the 100 clinical samples included in the study. St. John's Wort oil used in these 10 samples showed the most effective antibacterial effect of 7.81 µg/mL against Staphylococcus haemolyticus and Enterobacter aerogenes. Garlic oil showed the most effective antibacterial effect against Escherichia coli and Staphylococcus haemolyticus at 7.81 µg/mL. Nigella sativa oil showed the most effective antibacterial effect against Staphylococcus haemolyticus at 3.9 µg/mL. Orange Peel oil showed the most effective antibacterial effect against Enterococcus faecalis at 1.95 µg/mL. The minimum inhibition concentration at which the oils were effective on microorganisms was determined by comparing them with standard control strains. Conclusion: More clinical isolates and high-dose studies are needed to determine the effectiveness of plant extract oils. Garlic oil Escherichia coli, Staphylococcus haemolyticus and Enterobacter aerogenes, St. John's wort oil Staphylococcus haemolyticus and Enterobacter aerogenes, Nigella sativa) oil on Staphylococcus haemolyticus has been found to be effective

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“…Cuminaldehyde (4-isopropyl benzaldehyde) is an important component of essential oils that also contain p-cymene, -terpinene, -pinene, and p-mentha-1,3-dien 7-al and other useful compounds, with concentrations changing greatly depending on the plant's place of origin, mode of growth, harvesting, and extraction [20]. Kocoglu E, et al [21] developed an oval biorefi nery approach and applied to cumin seed (Cuminum cyminum) as a potential source of phytochemicals of interest [22]. Cumin is a popular spice that is widely used for its unique aroma [23], rich in vegetables and essential oils.…”

Section: Chemical Compositionsmentioning

confidence: 99%

Health Benefits of Cumin in Foods: A Review

Garg

2023

J Biomed Res Environ Sci

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Spices are parts of plants that are used in flavoring food and beverages, preservatives, and medications because of their phytochemicals or secondary metabolites. Cumin is a natural fragmented medicinal herb that is prepared from dried seeds of Cuminum cyminum L. plants belonging to the Apiaceae family. Cumin is used as a traditional healing material and has been used for a long time in many parts of the world to treat a variety of ailments. Cumin has proven to have a number of health benefits when it comes to preventing and treating a variety of diseases, including cancer, aging, metabolic, neurological, cardiovascular, and inflammatory diseases. Cumin has long been known to provide health advantages since it possesses the chemicals like phenylpropanoids, terpenes, flavonoids, and anthocyanins. People in India are using cumin to treat conditions ranging from indigestion and diarrhea to headaches. Recent research has shown that cumin is a beneficial herb with therapeutic characteristics and can be employed in the preparation of several medically significant foods. It has antimicrobial activity and adds alkaline value to the food.

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In Vitro Investigation of the Antibacterial Activity of Nigella sativa Oil on Some of the Most Commonly Isolated Bacteria in Otitis Media and Externa

Abstract: Aims and Scope Eurasian Journal of Medicine (Eurasian J Med) is an international, scientific, open access periodical published by independent, unbiased, and tripleblinded peer-review principles. The journal is the official publication of

Cited by 6 publications

References 19 publications

Therapeutic effect of Nigella sativa oil and ciprofloxacin against bacterial infection based on interleukin 1β expression and kidney histopathological alterations in Oreochromis niloticus

Therapeutic effect of Nigella sativa oil and ciprofloxacin against bacterial infection based on interleukin 1β expression and kidney histopathological alterations in Oreochromis niloticus

Determination of Antibacterial Activity of St. John's Wort (Hypericum perforatum L.) Oil, Nigella Sativa Oil, Clove (Eugenia caryophyllata) Oil, Orange Peel (Citrus sinensis) and Garlic (Allium sativa) Oil Against Microorganisms Isolated From Clinical Samples

Health Benefits of Cumin in Foods: A Review

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