Abstract:Background:
In patients with Gastroesophageal Reflux (GER), the digestive enzyme pepsin can reach the esophagus and extraesophageal sites and cause damages with the appearance of inflammation and other tedious symptoms.
Methods:
In this work, a number of biocompatible, non-toxic and hypoallergenic compounds were tested in vitro as inhibitors of pepsin. The residual enzyme activity in the presence of the investigated compounds was measured through a convenient and reliable UV-vis method based on the cleavage … Show more
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