In vitro investigation of fluoride ion release from four resin-modified glass polyalkenoate cements

Musa, Ali; Pearson, G.J.; Gelbier, Marilyn

doi:10.1016/0142-9612(96)84678-3

Cited by 27 publications

(18 citation statements)

References 13 publications

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“…Although various fluoridated materials have different rates and durations of fluoride release, most of the major fluoride release usually takes place in the first day or week. This holds true for fluoridated amalgam (Fazzi et al, 1977;Shannon and Miller, 1980), fluoridated resin composite (Swift, 1989;Ulukapi et al, 1996), and glass-ionomer cements (Diaz-Arnold et al, 1995;Musa et al, 1996). Although we recognize that amalgam corrosion products may not be present, we used a two-week aging period to circumvent the initial burst of fluoride release.…”

Section: Experimental Designsmentioning

confidence: 88%

Effects of Aged Fluoride-containing Restorative Materials on Recurrent Root Caries

et al. 1998

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Accumulated evidence has illustrated that secondary caries is the major reason for the failure of amalgam and resin composite restorations. The purpose of this study was to assess the cariostatic effects of aged fluoride-containing restorative materials on the formation of secondary root caries. Fifty sound human molars were selected and randomly assigned to five material groups: non-fluoride-containing amalgam (NA), fluoride-containing amalgam (FA), non-fluoride-containing composite (NC), fluoride-containing composite (FC), and glass-ionomer cement (GIC). After standardized class V cavity preparations and placement of restorations, teeth within each group were randomly divided into two subgroups, "non-aged" and "aged". The aged subgroup was immersed in an inorganic buffer solution for 2 wks before being thermocycled. After being thermocycled and subjected to four cycles of caries formation in a bacterial model system, the teeth were sectioned. Depths of outer lesions and areas of lesions on the cavity walls were measured by polarized light microscopy. The results showed that the FA and GIC groups, whether aged or not, had significantly smaller outer lesion depth than the non-fluoride-containing NA and NC groups. After aging, the FA group demonstrated significantly greater lesion depth (p = 0.0002), while the GIC group exhibited no significant changes in lesion depths. The NA group had a greater wall lesion area than the NC group, while both demonstrated no significant changes following 2 weeks of aging. The FA and GIC groups had similar inhibition areas along the cavity walls, whereas both inhibition areas increased significantly after the aging process. It is concluded that the fluoride-containing amalgam and the glass-ionomer cement, even after a two-week aging process, can still elicit a significant preventive effect on recurrent root caries in an in vitro bacterial model system.

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Section: Experimental Designsmentioning

confidence: 88%

Effects of Aged Fluoride-containing Restorative Materials on Recurrent Root Caries

et al. 1998

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“…The addition of resin to the material may influence its ability to release F; different resin chemistries, glass-ionomer chemistries, and the method of mixing can potentially alter the rate and extent of F release (Miller et al, 1995;Musa et al, 1996). In the absence of information regarding the specific chemistry of different product formulations, each material must be tested individually for F release.…”

Section: Introductionmentioning

confidence: 99%

Variability in Cytotoxicity and Fluoride Release of Resin-modified Glass-ionomer Cements

Kan

Messer

1997

J Dent Res

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New-generation glass-ionomer cements contain resin to improve their restorative properties. These resin-modified glass-ionomer cements vary considerably in their chemistry, which could result in corresponding variability in their physical and biological properties. This study investigated the cytotoxicity and the fluoride release of two resin-modified glass ionomers, a conventional glass-ionomer cement, and a resin composite. Samples were prepared and extracted in distilled water for 1, 4, and 7 days; eluates were filtered and tested by means of 3T3 mouse fibroblasts. Cytotoxicity (MTT assay) values were low for all materials and extraction times, indicating minimal cytotoxicity of all materials (less than 30% inhibition). Cytotoxicity of one resin-modified glass ionomer was significantly higher than for the other materials (p < 0.001). One resin-modified glass ionomer and the conventional glass-ionomer cement released significantly more fluoride at each time interval (p < 0.001) than the other resin-modified glass-ionomer cement and the resin composite. Fluoride release and cytotoxicity were correlated (r2 = 0.60; p < 0.001), although the fluoride release does not account for the cytotoxicity observed. Cytotoxicity and fluoride release suggest that one hybrid behaved more like a conventional glass ionomer, and the other like a resin composite. These differences may have implications for material selection in specific clinical situations.

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“…The first is the resin‐modified glass–ionomer, or a glass–ionomer modified by the addition of methacrylate resins. This hybrid of glass–ionomer offer longer working and controlled setting times, rapid development of strength, and lower sensitivity to environmental moisture changes, and can be finished and polished immediately after being light‐cured (Sidhu & Watson, 1995; Musa, Pearson & Gelbier, 1996). The second hybrid is the polyacid‐modified resin composite (or ‘compomer’), which contains some components of a glass–ionomer but lacks the typical glass–ionomer acid/base reaction during the initial setting process (McLean, Nicholson & Wilson, 1994).…”

Section: Introductionmentioning

confidence: 99%

Fluoride release and uptake by four new fluoride releasing restorative materials

Dionysopoulos

Kotsanos

Pataridou

2003

J of Oral Rehabilitation

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The present study compared the initial fluoride release and release following refluoridation of a conventional glass-ionomer Ketac-Molar (ESPE), a resin-modified glass-ionomer, Vitremer (3M), and two compomers F-2000 (3M) and Hytac (ESPE). Fifteen test specimens were prepared for each brand and immersed in deionized water. The fluoride released was measured every 2 days for 22 days. Refluoridation of the test specimens was done with solutions of 0.02, 0.04 and 0.2% NaF for 5 min on days 22, 30, 38 and 46. The fluoride released from recharged specimens was measured every 2 days until day 54. The fluoride release was highest during the first days after preparation, after which it decreased sharply and then more slowly. The four materials became 'recharged' with fluoride following repeated fluoride exposure in solution, the 0.2% solution being the most effective. From a clinical point of view, the results from this study imply that all the restorative materials tested may act as intra-oral devices for the controlled slow release of fluoride at sites at risk of recurrent caries. Fluoride release and uptake by four new fluoride releasing restorative materials.

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In vitro investigation of fluoride ion release from four resin-modified glass polyalkenoate cements

Cited by 27 publications

References 13 publications

Effects of Aged Fluoride-containing Restorative Materials on Recurrent Root Caries

Effects of Aged Fluoride-containing Restorative Materials on Recurrent Root Caries

Variability in Cytotoxicity and Fluoride Release of Resin-modified Glass-ionomer Cements

Fluoride release and uptake by four new fluoride releasing restorative materials

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