In vitro inhibition and dissolution of calcium oxalate by edible plant Trianthema monogyna and pulse Macrotyloma uniflorum extracts

Das, Ishwar; Gupta, Shailendra Kumar; Ansari, Shoeb A.; Pandey, V. N.; Rastogi, R. P.

doi:10.1016/j.jcrysgro.2004.09.038

Cited by 16 publications

(15 citation statements)

References 12 publications

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“…Urolithiasis is a consequence of complex physiochemical processes, and the major contributory factors are urinary supersaturation, crystallization, calculogenesis, and matrix formation. Various types of stones include calcium oxalate stones, struvite stones, uric acid stones, and cysteine stones with CaOx stones having the highest incidence of 75% in contrast to cysteine stones having incidence of 1-2% [10]. Various risk factors include hypercalciuria, hypercalcemia, hyperuricosuria, dehydration, anatomical abnormalities, increased urinary pH, and various drugs such as sulfonamides, corticosteroids, fluoroquinolones, tetracycline, and indinavir [11].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Antiurolithiatic Property of Ethanolic Extract of Fennel Seeds in Male Wistar Albino Rats

Poojar

Ommurugan

Adiga

et al. 2017

Asian J Pharm Clin Res

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Objective: Few studies have explored the diuretic property of fennel (Foeniculum vulgare). Hence, the aim of this study was to evaluate the antiurolithiatic property of ethanolic extract of fennel seeds in male Wistar albino rats.Methods: Prophylactic and curative urolithiasis models were used with 5 groups of 6 rats in each model. Ethanolic extract of fennel seeds in three doses 100, 200, and 300 mg/kg was used. Cystone 750 mg/kg was used as a standard drug. All drugs were administered orally. Zinc discs were surgically implanted in the bladder in all rats. After recovery, rats in the prophylactic model received three different doses of ethanolic extract of fennel seeds along with 1% ethylene glycol for 2 weeks whereas the rats in the other model received 1% ethylene glycol for 2 weeks followed by an ethanolic extract of fennel seeds in three doses for the next 2 weeks. Both models had a control group receiving 1% ethylene glycol. At the end of study period, rats were sacrificed and vesical calculi collected, weighed, and statistically evaluated using one-way ANOVA.Results: In both the models, all three doses of an extract of fennel seeds were effective in reducing stone formation as compared to control group with p<0.05. In both the models, all three test doses were comparable with cystone, but 300 mg/kg extract in prophylactic showed significance (p <0.05) when compared to standard.Conclusion: Fennel seeds can be used prophylactically as well as curatively in the treatment of urolithiasis. However, further studies and clinical trials are warranted to explore this property.

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Section: Introductionmentioning

confidence: 99%

Evaluation of Antiurolithiatic Property of Ethanolic Extract of Fennel Seeds in Male Wistar Albino Rats

Poojar

Ommurugan

Adiga

et al. 2017

Asian J Pharm Clin Res

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“…This resulted in a higher energy interface on the surface of SGP molecules. ions would then promote the formation of thermodynamically metastable COD [10]. Our findings indicate that natural substances such as SGP could contribute to the prevention of urinary stones.…”

Section: Conductivity Change With Timementioning

confidence: 72%

The Polysaccharide from the Seaweed Sargassum Graminifolium and its Effect on Calcium Oxalate Crystallization based on Determination of Electrical Conductivity

Zhang¹,

Miao²,

Wang³

et al. 2015

Proceedings of the 2015 International Conference on Industrial Technology and Management Science

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“…The extracts of horse gram were reported to possess anti-urolithiasis activity that was almost equivalent to cystone like marketed formulation for kidney stones 30 . It was also found that the horse gram extract is highly effective in the dissolution of calcium oxalate crystals and decrease their particle size considerably 31 .…”

Section: Antiurolithiatic and Anticalcifying Activitiesmentioning

confidence: 99%

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2019

IJPSR

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Macrotyloma uniflorum (Lam.) Verdc. also known as horse gram or Kulthi bean has been an underutilized legume crop with immense medicinal importance/potential. It is considered as a rich source of protein, vitamins, and minerals. It is characteristically known for its biotic and abiotic resistance, e.g., resistant to drought, salt, and insects. There are umpteen references available in the traditional medicinal system reverberating its medicinal significance. Its various bioactivities like anti-diabetic, analgesics, anticalcifying, anti-hypercholesterolemic, anti-obesity, antihelmintic, antioxidant, larvicidal and anorectic properties have already been reported. Despite being both sturdy and nutritive food crop, its consumption is very low. The present review attempts to compile medicinal uses of this crop to attract the people for its consumption. Its regular consumption not only adds to health benefits but also provides useful nutrition.

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In vitro inhibition and dissolution of calcium oxalate by edible plant Trianthema monogyna and pulse Macrotyloma uniflorum extracts

Cited by 16 publications

References 12 publications

Evaluation of Antiurolithiatic Property of Ethanolic Extract of Fennel Seeds in Male Wistar Albino Rats

Evaluation of Antiurolithiatic Property of Ethanolic Extract of Fennel Seeds in Male Wistar Albino Rats

The Polysaccharide from the Seaweed Sargassum Graminifolium and its Effect on Calcium Oxalate Crystallization based on Determination of Electrical Conductivity

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