2024
DOI: 10.1038/s41598-023-50134-z
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In vitro gastrointestinal gas monitoring with carbon nanotube sensors

Sahira Vasquez,
Martina Aurora Costa Angeli,
Andrea Polo
et al.

Abstract: In vitro simulators of the human gastrointestinal (GI) tract are remarkable technological platforms for studying the impact of food on the gut microbiota, enabling continuous and real-time monitoring of key biomarkers. However, comprehensive real-time monitoring of gaseous biomarkers in these systems is required with a cost-effective approach, which has been challenging to perform experimentally to date. In this work, we demonstrate the integration and in-line use of carbon nanotube (CNT)-based chemiresitive g… Show more

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Cited by 2 publications
(2 citation statements)
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“…These findings suggest that the material could be applied to the detection of gases associated with gastrointestinal diseases. Vasquez et al [119] designed a chemical gas sensor based on carbon nanotubes (CNTs) coated with a thin film of polydimethylsiloxane (PDMS), which is capable of continuous gas monitoring. The sensor was demonstrated to operate continuously for 16 h under anaerobic, high-humidity, and acidic conditions, making this design suitable for continuous monitoring in the complex environment of the intestine.…”
Section: Detection Of Intestinal Diseasesmentioning
confidence: 99%
“…These findings suggest that the material could be applied to the detection of gases associated with gastrointestinal diseases. Vasquez et al [119] designed a chemical gas sensor based on carbon nanotubes (CNTs) coated with a thin film of polydimethylsiloxane (PDMS), which is capable of continuous gas monitoring. The sensor was demonstrated to operate continuously for 16 h under anaerobic, high-humidity, and acidic conditions, making this design suitable for continuous monitoring in the complex environment of the intestine.…”
Section: Detection Of Intestinal Diseasesmentioning
confidence: 99%
“…Furthermore, the detection of new gas/vapours in unconventional environments (e.g. in vitro systems modelling the gastrointestinal tract where traditional sensors fail due to the harsh acidic and anaerobic conditions) makes CNTs ideal materials to develop next-generation gas sensors [441].…”
Section: Statusmentioning
confidence: 99%