In Vitro Flow Testing of Glaucoma Drainage Devices

Porter, Jeffrey M.; Krawczyk, Claudine H.; Carey, R. F.

doi:10.1016/s0161-6420(97)30077-3

Cited by 22 publications

(19 citation statements)

References 10 publications

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“…Hypotony rates range from 5% to 29% for the Ahmed implant 14,31,32 and 24% to 27% for the Krupin implant. 33,34 Other reported difficulties with valved implants include variable valve function, 35 variable valve resistance, 36 and late valve failure. 37,38 Finally, as increased plate surface area seems to improve IOP control up to a certain size, 39,40 valved implants may not achieve the same IOP as nonvalved implants with larger surface areas.…”

Section: Discussionmentioning

confidence: 99%

Tube Fenestrations in Baerveldt Glaucoma Implant Surgery: 1-year Results Compared with Standard Implant Surgery

Emerick

Gedde

Budenz

2002

Journal of Glaucoma

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Tube fenestrations provide safe and effective short-term intraocular pressure control with fewer glaucoma medications in a ligated nonvalved glaucoma drainage implant, with comparable intraocular pressure control and medications required at 1 year. However, not all patients have sustained reduction of intraocular pressure in the immediate postoperative period with fenestrations, making the effect somewhat unpredictable.

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Section: Discussionmentioning

confidence: 99%

Tube Fenestrations in Baerveldt Glaucoma Implant Surgery: 1-year Results Compared with Standard Implant Surgery

Emerick

Gedde

Budenz

2002

Journal of Glaucoma

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“…Constant-voltage schemes require a stable reference electrode in addition to the counter electrode, which makes this option less appealing for integrated and remotely operated systems. Both gravity and syringe-pump driven flow were used to characterize the valve performance (Porter et al, 1997). These can be easily achieved by using the setup shown in Fig.…”

Section: Resultsmentioning

confidence: 99%

Remotely adjustable check-valves with an electrochemical release mechanism for implantable biomedical microsystems

Pan

Baldi

Ziaie

2007

Biomed Microdevices

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In this paper, we present two remotely adjustable check-valves with an electrochemical release mechanism for implantable biomedical microsystems. These valves allow one to vary the opening pressure set-point and flow resistance over a period of time. The first design consists of a micromachined check-valve array using a SU-8 polymer structural layer deposited on the top of a gold sacrificial layer. The second design is based on a variable length cantilever beam structure with a gold sacrificial layer. The adjustable cantilever-beam structure is fabricated by gold thermo-compression bond of a thin silicon wafer over a glass substrate. In both designs, the evaporated gold can be electrochemically dissolved using a constant DC current via a telemetry link. In the first design the dissolution simply opens up individual outlets, while in the second design, gold anchors are sequentially dissolved hence increasing the effective length of the cantilever beam (reducing the opening pressure). A current density of 35 mA/cm 2 is used to dissolve the gold sacrificial layers. Both gravity and syringe-pump driven flow are used to characterize the valve performance. A multi-stage fluidic performance (e.g. flow resistance and opening pressure) is clearly demonstrated.

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“…5,[25][26][27] To our knowledge, this study is the first to report in vitro flow measurements of the Ex-PRESS miniature glaucoma device. Our experiment was based on a constant gravitational force of fluid flow test.…”

Section: Discussionmentioning

confidence: 99%

Comparative In Vitro Flow Study of 3 Different Ex-PRESS Miniature Glaucoma Device Models

Estermann

Yuttitham²,

Chen³

et al. 2013

Journal of Glaucoma

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In Vitro Flow Testing of Glaucoma Drainage Devices

Cited by 22 publications

References 10 publications

Tube Fenestrations in Baerveldt Glaucoma Implant Surgery: 1-year Results Compared with Standard Implant Surgery

Tube Fenestrations in Baerveldt Glaucoma Implant Surgery: 1-year Results Compared with Standard Implant Surgery

Remotely adjustable check-valves with an electrochemical release mechanism for implantable biomedical microsystems

Comparative In Vitro Flow Study of 3 Different Ex-PRESS Miniature Glaucoma Device Models

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