In Vitro Evaluation of Total Phenolics and Antioxidant Activities of Withania Somnifera, Eclipta Prostrata L and Gossypium Herbasceum L

Rifat-uz-Zaman,; Ghaffar, Maida; Fayyaz, Tehrim; Mehdi, Shumaila

doi:10.21065/19204159.3.9

Cited by 3 publications

(2 citation statements)

References 37 publications

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“…DPPH free radical scavenging activity of aqueous extract of Withania somnifera ranged from 13.80 to 61.44 % at concentrations levels from 100 to 1000 µg/mL [15]. DPPH free radical scavenging activity of ethanolic extracts of ashwagandha roots of various genotypes/varieties: In present studies, DPPH free radical scavenging activity (%) of the ethanolic extracts of ashwagandha roots increased with increase of concentration levels ( Table-5 [14]. DPPH free radical scavenging activity of hydroalcoholic extract of Withania somnifera ranged from 26.58 to 67.38 % at concentrations levels from 100 to 1000 µg/mL [15].…”

Section: Dpph Free Radical Scavenging Activity Of Aqueous Extracts Ofmentioning

confidence: 62%

“…Other research workers have also reported similar findings. Antioxidant activity of aqueous extract of Withania somnifera roots have been reported to range from 22.52 to 72.40 % at concentrations ranging from 10 to 250 µg/mL [14]. DPPH free radical scavenging activity of aqueous extract of Withania somnifera ranged from 13.80 to 61.44 % at concentrations levels from 100 to 1000 µg/mL [15].…”

Section: Dpph Free Radical Scavenging Activity Of Aqueous Extracts Ofmentioning

confidence: 99%

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Determination of Total Phenolics, Total Flavonoids and Evaluation of DPPH Free Radical Scavenging Activity of Ashwagandha (Withania somnifera L.) Roots

Gulati¹,

Madan²,

Jangra³

et al. 2017

Asian J. Chem.

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INTRODUCTIONPlant-based traditional medicine system continues to play a vital role in the health care system with about 60 % of the world inhabitants relying mainly on traditional medicines for their primary health care. Modern knowledge on medicinal plant research still contains at least 25 % drugs and many others, which are synthetic analogues, built on prototype compounds isolated from medicinal plants. The ongoing growing recognition of medicinal plants is due to escalating faith in herbal medicine [1]. The medicinal plant products, which are derived from plant parts such as stem, bark, leaves, fruits and seeds have been part of phytomedicine that produce a definite physiological action on human body. The most important of these natural bioactive constituents of plants are alkaloids, tannins, flavonoids and phenolic compounds [2]. Medicinal plants also contain large amounts of antioxidants, such as polyphenols, vitamin C, vitamin E, selenium, β-carotene, lycopene, lutein and other carotenoids, which play important roles in adsorbing and neutralizing free radicals, quenching singlet and triplet oxygen or decomposing peroxides [3].Among various medicinal plants, Withania somnifera is a popular Indian medicinal plant belonging to family Solanaceae and is also known as Ashwagandha, Indian ginseng and Winter cherry. It is an important herb in the ayurvedic and indigenous medical system. This plant grows widely in all drier parts of The present study was performed to estimate the total phenolics, total flavonoids and to evaluate the antioxidant activity of aqueous and ethanolic extracts of ashwagandha (Withania somnifera L.) roots of promising genotypes viz. HWS-08-14, HWS-08-18, HWS-1228, HWS-1229 and Selection-2B & varieties JA-20 and RVA-100. The results revealed that the extract yield of aqueous extracts (9.95 g/100 g) was higher than ethanolic extracts (3.96 g/100 g). Aqueous extracts contained the higher amount of total phenolics (3.58 mg GAE/g d.w.b.) than ethanolic extracts (2.19 mg GAE/g d.w.b.) whereas ethanolic extracts contained the higher amount of total flavonoids (1.16 mg CE/g d.w.b.) than aqueous extracts (0.82 mg CE/g d.w.b.). DPPH free radical scavenging activity of ashwagandha extracts varied widely and it increased with increase of concentration levels. Among aqueous and ethanolic extracts, aqueous extracts exhibited higher antioxidant activity. Hence, aqueous extracts of ashwagandha roots are better source of antioxidants in comparison to ethanolic extracts.

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Section: Dpph Free Radical Scavenging Activity Of Aqueous Extracts Ofmentioning

confidence: 62%

Section: Dpph Free Radical Scavenging Activity Of Aqueous Extracts Ofmentioning

confidence: 99%

Determination of Total Phenolics, Total Flavonoids and Evaluation of DPPH Free Radical Scavenging Activity of Ashwagandha (Withania somnifera L.) Roots

Gulati¹,

Madan²,

Jangra³

et al. 2017

Asian J. Chem.

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Nutritional composition, antioxidant activity and gossypol level of Nazilli glandless cottonseed, cottonseed kernel and their cold-pressed meal

Canikli¹,

Yıldırım²,

Erdem³

et al. 2023

Beni-Suef Univ J Basic Appl Sci

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Background The study was conducted to determine the nutrient composition and gossypol levels of glandless cottonseed (GCS), glandless cottonseed kernel (GCSK) glandless cottonseed meal (GCSM) and cottonseed kernel meal (GCSKM) obtained by cold pressing of cotton seeds and kernels (Glandless Nazilli variety) as a raw material of compound feed industry. Result Feed and dry matter (DM)-based nutrient analyses showed significant differences (p < 0.05) in DM, OM (organic matter), CP (crude protein), EE (ether extract), ash and NFE (nitrogen-free extract) contents between GCS and GCSK. The DM-based K, P, S, Mg, Ca, Na, Fe, Cu, Zn and Al contents were significantly different (p < 0.05) between GCS and GCSK. The concentrations of nonessential heavy metals (Cd, Pb, Ni and Al) in GCS, GCSK, GCSM and GCSKM samples were below the permissible limits. The linoleic acid (C18:2; ω6) was the main component (55.55%) among the 20 fatty acids identified in GCS oil. The level of unsaturated fatty acids (70.78%) was higher than that of saturated fatty acids (29.22%). Total phenolics concentrations of GCS, GCSK, GCSM and GCSKM samples were 7.87, 2.18, 5.86 and 1.91 mg gallic acid equivalents (GAE)/g, respectively. Free and total gossypol levels of GCS and GCSK were 294 and 440, and 521 and 706 mg/kg, respectively. Conclusion The results revealed that nutritional properties of Nazilli GCS with low gossypol and high linoleic acid content were relatively higher compared to the other meals investigated. The antioxidant activity of phenolic compounds, albeit at low levels in Nazilli GCS and GCSM, may contribute to animal health and production efficiency when used in animal rations.

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Prevalence and Risk Factors of Antitubercular Drug-Induced Hepatitis in Urban Population of Bahawalpur District, Punjab-Pakistan

Zaman¹

2011

J App Pharm

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In Vitro Evaluation of Total Phenolics and Antioxidant Activities of Withania Somnifera, Eclipta Prostrata L and Gossypium Herbasceum L

Cited by 3 publications

References 37 publications

Determination of Total Phenolics, Total Flavonoids and Evaluation of DPPH Free Radical Scavenging Activity of Ashwagandha (Withania somnifera L.) Roots

Determination of Total Phenolics, Total Flavonoids and Evaluation of DPPH Free Radical Scavenging Activity of Ashwagandha (Withania somnifera L.) Roots

Nutritional composition, antioxidant activity and gossypol level of Nazilli glandless cottonseed, cottonseed kernel and their cold-pressed meal

Prevalence and Risk Factors of Antitubercular Drug-Induced Hepatitis in Urban Population of Bahawalpur District, Punjab-Pakistan

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