In Vitro evaluation of remineralization potential of novamin on artificially induced carious lesions in primary teeth using scanning electron microscope and vickers hardness

Gangwar, Anshul; Jha, Kaushal Kishor; Thakur, Jyoti; Nath, Madhuri

doi:10.4103/ijdr.ijdr_326_16

Cited by 13 publications

(19 citation statements)

References 11 publications

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“…This result is a statistically significant difference and demonstrates that fluoride and NovaMin both trigger the remineralization process, as illustrated in the individual testing of these agents in prior studies with both permeant and primary teeth. 9,16,17,18,19 NovaMin is an inorganic and synthetic compound, which releases sodium, calcium, phosphate, and silica when it exposed to an aqueous media, increases pH and forms Hydroxycarbonateapatite crystals, and thus initiates the remineralization process. 20,21,22 The pairwise comparisons showed of this study illustrate that there are no statistically significant differences between NovaMin and fluoride in SMH values.…”

Section: Discussionmentioning

confidence: 99%

“…Specimens were then rinsed with 10 mL deionized water and immersed for 22 hours in 20 mL of remineralization solution (2 mM CaCl 2 , 2 mM NaH 2 Po 4 , with the addition of 0.1M NaOH to pH 6.8) at room temperature. 9 The teeth were then subjected to the de/ remineralization solutions three times to create artificial carious lesions. 9 Then SMH was measured to all specimens under the same conditions.…”

Section: Baseline Vickers Surface Microhardness Testingmentioning

confidence: 99%

“…9 The teeth were then subjected to the de/ remineralization solutions three times to create artificial carious lesions. 9 Then SMH was measured to all specimens under the same conditions. Samples were then stored in deionized water, which was replaced daily until remineralization agents were applied.…”

Section: Baseline Vickers Surface Microhardness Testingmentioning

confidence: 99%

“…The remineralization cycle was repeated twice daily for 10 days. 9 All teeth were then soaked in deionized water until SMH was measured to determine the acquired microhardness.…”

Section: Remineralization Cyclementioning

confidence: 99%

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Comparative Remineralization Efficacy of Topical NovaMin and Fluoride on Incipient Enamel Lesions in Primary Teeth: Scanning Electron Microscope and Vickers Microhardness Evaluation

2020

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Objective Evaluating the potential remineralization effect of NovaMin prophylaxis paste on artificial enamel lesions in primary teeth using Vickers microhardness and scanning electron microscope. Materials and Methods Forty sound buccal and lingual surfaces of human primary canine teeth were randomly divided into two groups after creating artificially demineralized lesions (G1: NovaMin and G2: fluoride; 20 per group) and then treated with the respective remineralization agents. The remineralization cycle repeated twice daily for 10 days. The groups were evaluated with Vickers microhardness and scanning electron microscope before and after de/remineralization. Results Statistically significant difference of microhardness was observed between demineralized enamel and remineralized enamel with group 1 and group 2 (p = 0.000 and p = 0.000, respectively). No statistically significant difference of microhardness was observed between two remineralized agents (p = 0.368). Conclusion Within the limitation of this in vitro study, NovaMin enhances the remineralization process equally to fluoride.

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Section: Discussionmentioning

confidence: 99%

Section: Baseline Vickers Surface Microhardness Testingmentioning

confidence: 99%

Section: Baseline Vickers Surface Microhardness Testingmentioning

confidence: 99%

“…The remineralization cycle was repeated twice daily for 10 days. 9 All teeth were then soaked in deionized water until SMH was measured to determine the acquired microhardness.…”

Section: Remineralization Cyclementioning

confidence: 99%

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Comparative Remineralization Efficacy of Topical NovaMin and Fluoride on Incipient Enamel Lesions in Primary Teeth: Scanning Electron Microscope and Vickers Microhardness Evaluation

2020

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“…It has been reported that the average of Vickers microhardness number of sound enamel will fall between 250 and 360 [24,25] . The baseline hardness number of all the enamel blocks in this study yielded measurements in the same range with no significant difference between any of the tested groups.…”

Section: Discussionmentioning

confidence: 99%

In-Vitro Assessment of The Effect of Different Remineralizing agents on Caries-Like Lesions in Primary Teeth

El-Geleel

Ghazawy

2022

Egyptian Dental Journal

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Objective:The objective of this study is to evaluate and compare the effect of different remineralizing agents on early enamel lesions in primary teeth using Vickers microhardness testing. Methodology:This in-vitro experimental study included fifty primary anterior teeth. Early enamel lesions were created by placing the samples in demineralizing solution for 4 days, then the specimens were randomly divided into 5 groups according to variable testing agent (control, sodium fluoride, CCP-ACP, CCP-ACP/F, nHAp) which were applied throughout a pH-cycling model. Surface microhardness was measured at three time points, at baseline, following demineralization and finally after pH-cycling (SMH-B, SMH-D and SMH-R), then percent microhardness recovery was calculated (%HR).Results: Data was analyzed using Kruskal-Wallis test for multiple-groups followed by Mann Whitney U test for two-group comparisons. There was no statistically significant difference between the groups at baseline and demineralization measurements. However, a statistically significant difference was detected between the groups after pH-cycling, such that the control group recorded the least mean hardness number, followed by the CCP-ACP group. At the same time, there was no statistically significant difference between the groups of NaF, CPP-ACP/F and nHAp groups. Similarly, %HR statistical relation followed the same pattern as the SMH-R. Conclusions:Based on the results of this study, it can be concluded that nHAp toothpate, CCP-ACP/F and (1000 ppm) fluoridated toothpaste are more effective than CCP-ACP in early enamel lesions remineralization.

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Evaluation of the effectiveness of Er: YAG laser and calcium sodium phosphosilicate (Novamine) prophylaxis paste on remineralization of incipient enamel lesions in primary teeth: An in-vitro study

Shihabi

Abo-Arraj

Goodson

et al. 2020

Pediatric Dental Journal

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In Vitro evaluation of remineralization potential of novamin on artificially induced carious lesions in primary teeth using scanning electron microscope and vickers hardness

Cited by 13 publications

References 11 publications

Comparative Remineralization Efficacy of Topical NovaMin and Fluoride on Incipient Enamel Lesions in Primary Teeth: Scanning Electron Microscope and Vickers Microhardness Evaluation

Comparative Remineralization Efficacy of Topical NovaMin and Fluoride on Incipient Enamel Lesions in Primary Teeth: Scanning Electron Microscope and Vickers Microhardness Evaluation

In-Vitro Assessment of The Effect of Different Remineralizing agents on Caries-Like Lesions in Primary Teeth

Evaluation of the effectiveness of Er: YAG laser and calcium sodium phosphosilicate (Novamine) prophylaxis paste on remineralization of incipient enamel lesions in primary teeth: An in-vitro study

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