In vitro evaluation of microbial D- and L-lactate production as biomarkers of infection
Paula Morovic,
Mercedes Gonzalez Moreno,
Andrej Trampuz
et al.
Abstract:Mammalian cells produce and metabolize almost exclusively L-lactate, bacterial species have the capacity to produce both D-lactate and L-lactate. The aim of this study was to evaluate the intrinsic production of D- and L-lactate in the most common pathogenic microorganisms causing septic arthritis (SA) and periprosthetic joint infection (PJI) as a potential biomarker for the diagnosis of infection. Following microorganisms were grown according to ATCC culture guides and tested for production of D- and L-lactat… Show more
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