In vitro evaluation of antibiofilm activity of crude extracts from macroalgae against pathogens relevant in aquaculture

Zammuto, Vincenzo; Rizzo, Maria Giovanna; Spanò, Antonio; Genovese, Giuseppa; Morabito, Marina; Spagnuolo, Damiano; Capparucci, Fabiano; Gervasi, C.A.; Smeriglio, Antonella; Trombetta, Domenico; Guglielmino, Salvatore; Nicolò, Marco Sebastiano; Gugliandolo, Concetta

doi:10.1016/j.aquaculture.2021.737729

Cited by 24 publications

(17 citation statements)

References 56 publications

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“…The different physico-chemical properties displayed by polysaccharides shows potential use in the development of matrices for vaccine micro-encapsulation (Borgogna et al, 2011), functional bio-composites (Paolucci et al, 2015), prebiotics (Vidhya Hindu et al, 2019), and anti-biofilm agent (Zammuto et al, 2022) for aquaculture purposes. In fact, Artemia nauplii encapsulated with the unidentified crude polysaccharide of the red seaweed Amphiroa fragilissima for the feeding of the shrimp Litopenaeus vannamei enhanced its growth, biochemical composition, digestive enzyme activities and antioxidant properties which led to the improvement of larval quality (Muttharasi et al, 2021).…”

Section: Potential Based On Results Of Other Speciesmentioning

confidence: 99%

Valorization of the chemical diversity of the tropical red seaweeds Acanthophora and Kappaphycus and their applications in aquaculture: A review

Guillen

Motti²,

Mangelinckx³

et al. 2022

Front. Mar. Sci.

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The role that seaweeds play as primary producers and ecosystems engineers in marine coastal ecosystems is widely acknowledged. Seaweeds, however, are also important drivers in the development of the blue bioeconomy due to their vast diversity of unique chemicals with a broad range of industrial and biotechnological applications. In tropical regions, seaweed production has been focused on a few species only, because of their hydrocolloids used in the food industry. There is a strong need to identify new applications of red seaweed species in other sectors such as aquaculture. Therefore, to diversify the culture of red seaweeds, more tropical species need to be investigated for their chemical composition and potential application in aquaculture, and then, to develop a method for a sustainable cultivation of new seaweed candidates and enhance their economic potential. Based on this context, we analyze the potential value of the red edible seaweed Acanthophora spp., an under-valued seaweed species which is naturally abundant in tropical countries, and Kappaphycus spp., a commercially valuable seaweed commonly used for polysaccharide extraction. The vast chemical diversity of seaweeds (polysaccharides, phytohormones, amino acids, and pigments) has led to research on a wide range of applications in aquaculture, including pathogen control, immunostimulant, antioxidant, bioremediation, feed, UV protectants, increase in seafood shelf life, animal colorant, and growth regulator for microalga culture. This review hopes to stimulate the interest among seaweed researchers to investigate other local seaweed species and seek greater added value of their biomass and chemical compounds and their applications in the aquaculture sector. Additionally, this information will help stakeholders to benefit from these two red seaweeds by contributing to the diversification of the blue bioeconomy in tropical countries.

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Section: Potential Based On Results Of Other Speciesmentioning

confidence: 99%

Valorization of the chemical diversity of the tropical red seaweeds Acanthophora and Kappaphycus and their applications in aquaculture: A review

Guillen

Motti²,

Mangelinckx³

et al. 2022

Front. Mar. Sci.

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show abstract

“…Inhibition of bacterial adhesion can be achieved by surface coating with biocidal agents or specific polymers having an ability to inhibit the cells impending the surface. Indeed, novel polysaccharides from Antarctic sponge-associated bacteria and lake macroalgae have recently been used to hinder the adhesion of bacteria [107,108]. Surface topography using nanotechnology has recently been explored to generate antibacterial surfaces [109][110][111][112].…”

Section: Bacterial Surface Attachment Inhibitionmentioning

confidence: 99%

Development of Antibiofilm Therapeutics Strategies to Overcome Antimicrobial Drug Resistance

et al. 2022

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A biofilm is a community of stable microorganisms encapsulated in an extracellular matrix produced by themselves. Many types of microorganisms that are found on living hosts or in the environment can form biofilms. These include pathogenic bacteria that can serve as a reservoir for persistent infections, and are culpable for leading to a broad spectrum of chronic illnesses and emergence of antibiotic resistance making them difficult to be treated. The absence of biofilm-targeting antibiotics in the drug discovery pipeline indicates an unmet opportunity for designing new biofilm inhibitors as antimicrobial agents using various strategies and targeting distinct stages of biofilm formation. The strategies available to control biofilm formation include targeting the enzymes and proteins specific to the microorganism and those involved in the adhesion pathways leading to formation of resistant biofilms. This review primarily focuses on the recent strategies and advances responsible for identifying a myriad of antibiofilm agents and their mechanism of biofilm inhibition, including extracellular polymeric substance synthesis inhibitors, adhesion inhibitors, quorum sensing inhibitors, efflux pump inhibitors, and cyclic diguanylate inhibitors. Furthermore, we present the structure–activity relationships (SAR) of these agents, including recently discovered biofilm inhibitors, nature-derived bioactive scaffolds, synthetic small molecules, antimicrobial peptides, bioactive compounds isolated from fungi, non-proteinogenic amino acids and antibiotics. We hope to fuel interest and focus research efforts on the development of agents targeting the uniquely complex, physical and chemical heterogeneous biofilms through a multipronged approach and combinatorial therapeutics for a more effective control and management of biofilms across diseases.

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“…Furthermore, numerous studies have revealed the potential of medicinal herbs for aquaculture uses; thus, researchers have developed new and improved approaches for antibacterial discoveries from plants. For instance, antibacterial properties were characterized in polysaccharides derived from macroalgae, Chaetomorpha aerea ( 65 ) and nanoscale silver particles of butter fruit, Persea americana ( 66 ). These studies highlighted future research prospects for plant-based polysaccharide-derived compounds and nano-synthetic substances.…”

Section: Antibacterial Activity Of Medicinal Herbs In Aquaculturementioning

confidence: 99%

Role of phytobiotics in relieving the impacts of Aeromonas hydrophila infection on aquatic animals: A mini-review

Kari

Wee²,

Sukri³

et al. 2022

Front. Vet. Sci.

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Aeromonas hydrophila is a ubiquitous bacterium with various hosts that causes mass mortality in farm-raised fish species and significant economic losses. The current antibiotic treatment is ineffective in controlling this bacterium infection in aquaculture species. Therefore, an evaluation of potential phytobiotics is needed to find an alternative antimicrobial agent to reduce the over-reliance on antibiotics in aquaculture and safeguard public and environmental health. Furthermore, the rise in antibiotic resistance cases among pathogenic bacteria indicates an urgent need for new fish and shellfish health management solutions. In this context, phytobiotics applications in aquaculture can be defined as any medicinal plant-based antimicrobial agent used in fish and shellfish health management. This review will focus on the impacts of Motile Aeromonas Septicemia (MAS) due to A. hydrophila in aquaculture, the potential of phytobiotics in enhancing the tolerance of aquaculture species against MAS and the combination of phytobiotics with other antimicrobial and therapeutic agents against MAS.

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In vitro evaluation of antibiofilm activity of crude extracts from macroalgae against pathogens relevant in aquaculture

Cited by 24 publications

References 56 publications

Valorization of the chemical diversity of the tropical red seaweeds Acanthophora and Kappaphycus and their applications in aquaculture: A review

Valorization of the chemical diversity of the tropical red seaweeds Acanthophora and Kappaphycus and their applications in aquaculture: A review

Development of Antibiofilm Therapeutics Strategies to Overcome Antimicrobial Drug Resistance

Role of phytobiotics in relieving the impacts of Aeromonas hydrophila infection on aquatic animals: A mini-review

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