Abstract:This study shows first in vitro tests of a nitinol based vein cuff developed for external valvuloplasty. In contrary to currently existing vein cuffs the tested model enables minimal invasive implantation and also maintains its round pre-shaped profile at body temperature (37 • C). The examination of the cuff surface structure by scanning electron microscopy, profilometry and X-ray photoelectron spectroscopy after sterilization with ethylene oxide and before cyto-compatibility testing revealed a nearly smooth … Show more
“…Furthermore, no significant cytotoxic effect was observed (MTS test). 27 In an in vitro test set-up designed to analyse cuff functionality, the cuff successfully limited dilation of varicose veins (human vena saphena magna ) at physiological blood pressures (<120 mmHg) and also in case of hypertonia (300 mmHg) to the inner diameter determined by the cuff. In this follow-up in vivo study, limited dilation of varicose veins was confirmed again.…”
“…Furthermore, no significant cytotoxic effect was observed (MTS test). 27 In an in vitro test set-up designed to analyse cuff functionality, the cuff successfully limited dilation of varicose veins (human vena saphena magna ) at physiological blood pressures (<120 mmHg) and also in case of hypertonia (300 mmHg) to the inner diameter determined by the cuff. In this follow-up in vivo study, limited dilation of varicose veins was confirmed again.…”
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