Abstract:Background: Cystic echinococcosis (CE), a widespread helminthic disease caused by the larval stage of the dog tapeworm Echinococcus granulosus is represented as a public health concern in humans. The therapeutic failure of albendazole (ABZ) against CE depends on its low aqueous solubility and consequently its erratic bioavailability in plasma. Serious adverse effects have been also observed following the long-term use of ABZ in vivo. Methods: We evaluated the apoptotic effects of ABZ-loaded β-cyclodextrin (ABZ… Show more
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