In vitro efficacy of a povidone–iodine 0.4% and dexamethasone 0.1% suspension against ocular pathogens

Pelletier, Jesse; Miller, Darlene; Liang, Baoyu; Capriotti, Joseph

doi:10.1016/j.jcrs.2010.11.028

Cited by 28 publications

(19 citation statements)

References 13 publications

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“…Key features of the study were the provision of the same, continuous prophylactic regimen for every patient, with progression from antibacterial prophylaxis alone in the first era to more comprehensive polymicrobial prophylaxis in the latter era. [32][33][34] The majority of patients were compliant with the outpatient regimen, as confirmed by specific questions that were asked at the time of each outpatient visit. Every patient with a postoperative infection had been compliant with the follow-up schedule, although several were at, or just beyond, the 3-month follow-up interval when presenting with asymptomatic infections.…”

Section: Discussionmentioning

confidence: 99%

Microbial Keratitis and Endophthalmitis After the Boston Type 1 Keratoprosthesis

Wagoner

Welder

Goins

et al. 2016

Cornea

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Section: Discussionmentioning

confidence: 99%

Microbial Keratitis and Endophthalmitis After the Boston Type 1 Keratoprosthesis

Wagoner

Welder

Goins

et al. 2016

Cornea

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“…The addition of an antibiotic with better gram-negative coverage could help decrease the risk of postoperative bacterial endophthalmitis. Similarly, topical povidone-iodine is a potent antiseptic against bacteria and fungi that could be used intermittently to disinfect the ocular surface 34. Such regimens should be evaluated in larger randomised studies before their implementation as a part of the routine prophylaxis post-KPro.…”

Section: Discussionmentioning

confidence: 99%

Review of endophthalmitis following Boston keratoprosthesis type 1: Table 2

2012

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Endophthalmitis remains one of the most damaging and challenging complications following Boston keratoprosthesis type 1 (KPro) surgery. The authors reviewed the literature from 2001 onward to identify cases of endophthalmitis following KPro surgery and present an additional case of endophthalmitis in a patient with Stevens Johnson syndrome. The prevalence of endophthalmitis between 2001 and 2011 was 5.4%. Gram-positive bacteria are the most common agents responsible for endophthalmitis in this patient population while gram-negative bacteria and fungi are emerging pathogens. Risk factors for endophthalmitis include preoperative diagnosis of cicatricial disease and postoperative infectious keratitis, glaucoma drainage device erosion and non-compliance with antibiotic prophylaxis. Additional studies on the prevention and treatment of endophthalmitis are required to improve the overall prognosis of these patients.

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“…These organisms are resistant to extreme environmental conditions including unfavorable temperature, pH ranges and exposure to chemicals in cyst stage and they transfer to trophozoite when condition became favorable (Stockman et al, 2011) (Pelletier et al, 2011) Free living amoebae could be isolated from water resources, soil, sewage and even contact lens washing solution and dialysis machine (MarcianoCabral et al,2003). The most common cause of amoebic keratitis (AK) associated with Acanthamoeba is improper usage of soft contact lenses such as taking shower or swimming in suspected water sources while wearing lenses (Martinez AJ et al,1997) ( Radford CF et al,1992).…”

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confidence: 99%

High Occurrence of Potentially Pathogenic Free Living Amoebae in Water Bodies of Kaleybar and Khodaafarin, East Azerbaijan Province

Behniafar

Niyyati

Lasjerdi

et al. 2015

Curr. World Environ

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Free living amoebas are widespread protozoans that can be found in different environmental resources such as water bodies, soil and clays. Free living amoebae particularly Acanthamoeba could lead to diseases with poor prognosis including ameobic keratitis (AK) and granulomatous amebic encephalitis (GAE) especially in contact lens wears and immunocompromised individuals, respectively. In the present study 50 samples were collected from water resources (hot-springs, cold springs, rivers, wells, refined drinking water and subterranean canals) of Kaleybar and Khodaafarin, East Azarbayjan Province, Iran. The samples were transferred to laboratory and cultured on 1.5% nonnutrient agar medium containing Escherichia coli bacteria at room temperature and finally examined by microscopic methods. The results showed that out of 50 water samples, 40% were positive samples for free-living amoebae (FLA) including 60% Acanthamoebae genus, %35 Haetmannellidae, %20 Valkamphiids, %20 Vannella, %10 Thechamoeba (45% of plates had mix contamination). The present research was the first study to address the presence of potentially pathogenic free living amoebae in Kaleybar and Khodaafarin, East-Azerbaijan Province.

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In vitro efficacy of a povidone–iodine 0.4% and dexamethasone 0.1% suspension against ocular pathogens

Abstract: Drs. Pelletier and Miller have no financial or proprietary interest in any material or method mentioned. Additional disclosures are found in the footnotes.

Cited by 28 publications

References 13 publications

Microbial Keratitis and Endophthalmitis After the Boston Type 1 Keratoprosthesis

Microbial Keratitis and Endophthalmitis After the Boston Type 1 Keratoprosthesis

Review of endophthalmitis following Boston keratoprosthesis type 1: Table 2

High Occurrence of Potentially Pathogenic Free Living Amoebae in Water Bodies of Kaleybar and Khodaafarin, East Azerbaijan Province

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