Abstract:Leishmaniasis is a neglected disease that affects millions of people worldwide, and special attention should be given to treatment because the available drugs have limitations, which can lead to low therapeutic adherence and parasitic resistance. This study evaluated the activity of the bioactive naphthoquinones, lapachol and β-lapachone, against
Leishmania amazonensis
. The cell alterations were evaluated
in vitro
on promastigote and amastigote forms. The lethal d… Show more
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