In vitro effects of aqueous seeds extract of Acacia cyanophylla on the opsonized zymosan-induced superoxide anions production by rat polymorphonuclear leukocytes

Abbouyi, Ahmed El; Toumi, Mina; Hachimi, Y El; Jössang, Akino

doi:10.1016/j.jep.2003.12.005

Cited by 17 publications

(14 citation statements)

References 32 publications

(29 reference statements)

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“…According to some reports, the presence of hydrolyzable tannins stimulates iodination of myeloperoxidase-rich granulocytic cells such as polymorphonuclear cells (Sakagami et al, 1990;El Abbaouyi et al, 2004). Moreover, tannins stimulate reactive oxygen intermediates production and mediate the release of a neutrophil chemotactic factor.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, tannins stimulate reactive oxygen intermediates production and mediate the release of a neutrophil chemotactic factor. Also, tannins enhance nitroblue tetrazolium (NBT)-reducing activity of macrophages (Sakagami et al, 1991), activate morphological change (spreading) of peritoneal macrophages and induce various antitumor cytokines such as tumor necrosis factor ␣ (TNF␣) and interleukin 1 (IL-1) (Feldman et al, 1999;El Abbaouyi et al, 2004).…”

Section: Discussionmentioning

confidence: 99%

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Immunostimulatory effects of Uncaria perrottetii (A. Rich.) Merr. (Rubiaceae) vinebark aqueous extract in Balb/C mice

Nudo

Catap

2011

Journal of Ethnopharmacology

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Immunostimulatory effects of Uncaria perrottetii (A. Rich.) Merr. (Rubiaceae) vinebark aqueous extract in Balb/C mice

Nudo

Catap

2011

Journal of Ethnopharmacology

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“…Acacia is used in traditional medicine for their antibacterian, antioxidant, anti-inflammatory, antispasmodic, anti-arythmique and astringent proprieties (El Abbouyi et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Fatty acids and triacylglycerols composition from Tunisian Acacia species seed oil

Youzbachi

Trabelsi

Elfalleh

et al. 2019

Arabian Journal of Chemistry

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Recently, plant seeds that have not been enough explored and exploited are cheap sources of a lot of natural molecules for industrial applications. The aim of the present study was to evaluate for the first time the composition of fatty acids and triacylglycerols (TAG) of mature unexploited seeds of some Acacia species (Acacia cyclops, Acacia ligulata and Acacia salicina) harvested in Tunisia in order to reveal their potential for human consumption.Results showed that, Acacia seed oils were mainly unsaturated (more than 71%). The polyunsaturated fatty acids were the major fractions (52-68%) with the linoleic acid as the major fatty acid (more than 52%), followed by oleic acid (15-27%) as monounsaturated fatty acid. The TAG composition was significantly different among the three Acacia species. PLL, PLO, LnLO, OLL, OOL, and OOO were the major forms. Acacia seed oil could be used as potential source of oil with high industrial value; nevertheless in vivo tests are essential to confirm its safety before use. Ó 2015 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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“…After centrifuging this at 1700 g for 15 min, the OZ was resuspended at a concentration of 10 mg/ml in PBS and stored at −80°C before use. [6] Isolation of PMNs PMNs were collected from the rat pleural cavity 4 h after injection of 1 ml of a 1% suspension of calcium pyrophosphate (CaPP) crystals in sterile PBS according to the modified technique described by Willoughby et al [7] Cells (95% PMNs) were washed twice in Hank's balanced salt solution, resuspended in PBS and stored at +4°C for O 2…”

Section: Preparation Of Opsonized Zymosanmentioning

confidence: 99%

Anti-inflammatory effect of hydromethanolic extract from Marrubium vulgare Lamiaceae on leukocytes oxidative metabolism: An in vitro and in vivo studies

Abbouyi¹,

Khyari²,

Eddoha³

et al. 2013

Int J Green Pharm

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Among its various use in folk medicine, the supposed anti-inflammatory activity has received our attention. Therefore, the current study was designed to investigate the in vitro and in vivo effect of hydromethanolic extract obtained from M. vulgare on the oxidative metabolism of pleural rat PMNs assessed by measurement of two metabolic parameters: O 2 consumption and O 2•− production.Anti-inflammatory effect of hydromethanolic extract from Marrubium vulgare Lamiaceae on leukocytes oxidative metabolism: An in vitro and in vivo studies original articlE Background: Marrubium vulgare Lamiaceae, known as white horehound, is frequently used in folk medicine to treat many illnesses from ancient times. Aims: The present study is conducted to evaluate the anti-inflammatory activity of hydromethanolic extract of the aerial part of M. vulgare. Materials and Methods: The oxygen consumption and the production of superoxide anions, by rat pleural polymorphonuclear leukocytes stimulated by opsonized zymosan, were performed. PMNs were collected after induction of an acute inflammatory reaction by injection, in the rat pleural cavity, of suspension of calcium pyrophosphate crystals. Plant extract was tested at a concentration range 10-100 mg/ml and 100-400 mg/kg/day for in vitro and in vivo assays respectively. Statistical analysis: All values are expressed as mean ± standard error. The significance of differences between control and treated samples in vitro was analysed using the Student's t-test. For in vivo studies, data were analysed using one-way analysis of variance. Differences with P ≤ 0.05 were considered to be statistically significant. Results: Hydromethanolic extract of M. vulgare showed, in vitro a significant anti-inflammatory effect in a dose-dependent manner. In vivo, only the high amounts of the plant extract (300 and 400 mg/kg/day) exhibited a significant anti-inflammatory effect. The plant extract contains a high amount of polyphenols. Conclusion: Hydromethanolic extract of M. vulgare had an anti-inflammatory effect, which corroborates the usefulness of this plant in the treatment of inflammatory disorders.

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In vitro effects of aqueous seeds extract of Acacia cyanophylla on the opsonized zymosan-induced superoxide anions production by rat polymorphonuclear leukocytes

Cited by 17 publications

References 32 publications

Immunostimulatory effects of Uncaria perrottetii (A. Rich.) Merr. (Rubiaceae) vinebark aqueous extract in Balb/C mice

Immunostimulatory effects of Uncaria perrottetii (A. Rich.) Merr. (Rubiaceae) vinebark aqueous extract in Balb/C mice

Fatty acids and triacylglycerols composition from Tunisian Acacia species seed oil

Anti-inflammatory effect of hydromethanolic extract from Marrubium vulgare Lamiaceae on leukocytes oxidative metabolism: An in vitro and in vivo studies

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