In vitro effects of Ag+ on planktonic and adhered cells of fluconazole-resistant and susceptible strains of Candida albicans, C. glabrata and C. krusei

Zhang, Shangtong; Ahearn, Donald G.; Mateus, Carolina; Crow, Sidney A.

doi:10.1016/j.biomaterials.2005.12.010

Cited by 7 publications

(5 citation statements)

References 40 publications

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“…The highest level of Ag in water of this study was in October, being significantly higher than in any other month (p \ 0.05). Green algae Chlamydomonas and Pseudokirchneriella subcapitata could be inhibited by exposure to dissolved Ag (Hiriart-Baer et al 2006), and there were variable Ag tolerances among diverse phytoplankton taxa (Zhang et al 2006). The maximum average concentrations of waterborne As, Cd, Cr of the present study were 4.3, 2.2, and 1.8 lg/L, respectively (Table 2), even though, which are below those for acceptable drinking water criteria of WHO (i.e., As 10 lg/L, Cd 3 lg/L, Cr 50 lg/L) and US EPA (i.e., As 10 lg/L, Cd 5 lg/L, Cr 100 lg/L) (Frisbie et al 2002).…”

Section: Resultsmentioning

confidence: 99%

Metals and Metalloids in the Water–Bloom-Forming Cyanobacteria and Ambient Water from Nanquan Coast of Taihu Lake, China

Liu

Yang

2012

Bull Environ Contam Toxicol

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Concentrations of 12 metal(oid)s were investigated in the bloom-forming cyanobacteria and ambient water samples collected monthly between March 2009 and February 2010 at the Nanquan coast of Taihu Lake, China. The metal(oid) concentrations in ambient water decreased in the order Fe > Zn > Ni ≈ As ≈ Cu > Mn > Ag > Cr > Se > Cd > Co > Tl, while those in cyanobacteria followed a sequence Fe > Mn > Zn > Cu ≈ Ni > Co > Ag > Cr ≈ As > Cd > Tl > Se. The metal(loid) burdens removed by cyanobacteria were estimated as 164 t Fe, 12.4 t Mn, 3.6 t Zn, 2.0 t Ni, 2.0 t Cu, 0.5 t As, 0.5 t Cr, 0.4 t Cd, 0.9 t Ag, 1.1 t Co, 0.2 t Tl, and 0.09 t Se during the 2008-2010 bloom seasons.

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Section: Resultsmentioning

confidence: 99%

Metals and Metalloids in the Water–Bloom-Forming Cyanobacteria and Ambient Water from Nanquan Coast of Taihu Lake, China

Liu

Yang

2012

Bull Environ Contam Toxicol

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“…Earlier studies 9 presented data showing that EDTA enhanced the activity of some antifungal compounds. EDTA enhances lactoferrin and amphotericin B activity against Escherichia coli O157 : H7 and Aspergillus species respectively 9–21 . Some of the goals of the present study were to determine whether EDTA would (a) significantly reduce the viability of the test fungi under the stated in vitro test conditions and (b) enhance the in vitro fungicidal activity of CAY‐1 employed at sub‐lethal concentrations against the six Aspergillus and Fusarium species.…”

Section: Discussionmentioning

confidence: 98%

“…In vitro , several compounds complexed with silver display lethality to Gram‐negative and Gram‐positive bacteria and Candida albicans. 18–20 …”

Section: Discussionmentioning

confidence: 99%

“…[4][5][6] In vitro, several compounds complexed with silver display lethality to Gram-negative and Grampositive bacteria and Candida albicans. [18][19][20] Earlier studies 9 presented data showing that EDTA enhanced the activity of some antifungal compounds. EDTA enhances lactoferrin and amphotericin B activity against Escherichia coli O157 : H7 and Aspergillus species respectively.…”

Section: Discussionmentioning

confidence: 99%

“…EDTA enhances lactoferrin and amphotericin B activity against Escherichia coli O157 : H7 and Aspergillus species respectively. [9][10][11][12][13][14][15][16][17][18][19][20][21] Some of the goals of the present study were to determine whether EDTA would (a) significantly reduce the viability of the test fungi under the stated in vitro test conditions and (b) enhance Saponins, such as CAY-1, are noted as membrane-disrupting compounds. We hypothesised that sub-lethal concentrations of CAY-1 would cause non-lethal perturbations in the fungal membranes.…”

Section: Discussionmentioning

confidence: 99%

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Silver enhances the in vitro antifungal activity of the saponin, CAY-1

Lucca

Boué

Sien

et al. 2009

Mycoses

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The fungicidal properties of purified CAY-1, dissolved silver ion and ethylenediamine tetraacetic acid (EDTA) separately were studied in vitro as were the abilities of silver and EDTA to enhance CAY-1 fungicidal properties. Non-germinated and germinating conidia of Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Fusarium verticillioides (Fusarium moniliforme), Fusarium oxysporum and Fusarium solani were incubated separately with CAY-1 (0-24.8 μg ml(-1)), silver (0-111.1 μg ml(-1)), and EDTA (0-2400 μg ml(-1)). Controls consisted of non-germinated or germinated conidia in test medium. To assess combined activity, compounds, based on the sub-lethal doses of each as defined in the initial experiments, were combined and tested in bioassays. Controls for the mixed sets consisted of non-germinated or germinated conidia only or with the sub-lethal CAY-1 test concentrations. The minimum inhibitory concentrations (MICs) for CAY-1 and silver, both separate and combined, were determined. Viability assays showed CAY-1 activity only against the germinating conidia of A. flavus, A. niger and F. solani. Silver was active against the germinating conidia of all fungi and the non-germinated conidia of F. oxysporum and F. solani. Combined silver and CAY-1 produced significant viability loss at concentrations not effective separately. EDTA was not fungicidal separately and did not enhance CAY-1 fungicidal properties. MIC data showed that CAY-1 plus silver had an additive effect. Results indicate that dissolved silver was fungicidal in vitro and enhanced the fungicidal properties of CAY-1 at concentrations ineffective when tested separately.

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Current awareness on yeast

2006

Yeast

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In order to keep subscribers up‐to‐date with the latest developments in their field, this current awareness service is provided by John Wiley & Sons and contains newly‐published material on yeasts. Each bibliography is divided into 10 sections. 1 Books, Reviews & Symposia; 2 General; 3 Biochemistry; 4 Biotechnology; 5 Cell Biology; 6 Gene Expression; 7 Genetics; 8 Physiology; 9 Medical Mycology; 10 Recombinant DNA Technology. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted. (4 weeks journals ‐ search completed 14th. June 2006)

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In vitro effects of Ag+ on planktonic and adhered cells of fluconazole-resistant and susceptible strains of Candida albicans, C. glabrata and C. krusei

Cited by 7 publications

References 40 publications

Metals and Metalloids in the Water–Bloom-Forming Cyanobacteria and Ambient Water from Nanquan Coast of Taihu Lake, China

Metals and Metalloids in the Water–Bloom-Forming Cyanobacteria and Ambient Water from Nanquan Coast of Taihu Lake, China

Silver enhances the in vitro antifungal activity of the saponin, CAY-1

Current awareness on yeast

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