Abstract:Summary
The study was performed to compare the dissolution rates of six of the popular brands of 100 mg phenylbutazone tablets available on the British market. The standard USP dissolution method was used for evaluation. The USP requires 60% of the labelled amount to dissolve in not more than 30 min. On this basis the performance of three brands was satisfactory, that of one brand marginal and two brands did not meet the USP requirements.
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