In Vitro Cytotoxicity Study of Pt Nanoparticles Decorated TiO2 Nanotube Array

Abstract

Titanium dioxide nanotubes were synthesized by anodizing Ti sheets in the ethylene glycol solution and were covered in Pt nanoparticles onto the surface of TiO2NTs using electrodeposition method from using five derivatives of Mannich base Pt complexes which have been used as precursor of platinum. The mean size, shape, elemental composition of the titanium dioxide nanotubes and platinum deposited on the template were evaluated by different techniques such as field emission scanning electron microscope (FE-SEM), transmission electron microscopy (TEM), X-ray diffraction pattern (XRD), and energy dispersive X-ray (EDX) technique. From all these analyses, the TiO2NTs prepared and Ptnanoparticles deposited on it were identified. The diagnoses proved that all the Pt nanoparticles have a size less than 50 nm. The MCF-7 cancer cell lines and WRL68 normal cell lines were treated with concentration 800, 400,200,100, 50, 25, 12.5µg\ml of TiO2NTs and Pt\TiO2NTs(1) and (2) for 48hours using MTT assay.IC50 and inhibition rate were calculated. The result shows that the Pt\TiO2NTs have more inhibition effect on cancer cell lines than TiO2NTs array.

Synthesis, Structural, Morphological Characterization, and Cytotoxicity Assays of Metal Complexes Decorated SiO2 Nanoparticles Against Breast Cancer Cell Lines (MDA-MB-231)

“…In this study, XRD data was utilized to not only confirm the formation of different phases but also to calculate the particle size of each specimen. By analyzing the main peaks of each sample, the Debye-Scherrer equation was employed to determine the average particle size 21 :…”

التحضير الحيوي والتشخيص ودراسات الامتزاز ومضاد الميكروبات لجسيمات اوكسيدالمنغنيز النانوية باستخدام مستخلص قشور الرمان

“…Table 2, Fig. 10 show the inhibition zone of growth in (mm) of MnO2 NPs against the bacterial pathogens, two Bactria, and one fungus [20][21][22][23][24] .…”

Biosynthesis, Characterization, Adsorption and Antimicrobial studies of zirconium oxide Nanoparticles Using Punica Granatum Extract

“…The first factor (charge) cannot be the primary cause of this difference because all ions have the same charge. Both the majority of the solution and the adsorbent mass are affected by size during the diffusion process [22][23][24][25][26]. This theory predicts that Co (II), Ni (II), and Cu should have the highest adsorption rates (II), but the rate of decrease in the Co (II) adsorption rate and also the unrestricted linear growth of an adsorbed component indicate that there is still another process taking place in addition to adsorption, and that is the Co (II) oxidation by metal oxide.…”