“…Docetaxel also has been shown to enhance response to radiation with induced mitotic arrest and apoptosis in murine tumor cells [12, 19]. The effects of taxane exposure have been studied with numerous human cell lines derived from tumors of the lung [15, 20–23], head and neck [24–27], brain [28, 17, 18], breast [15, 20, 29, 22], colon [29], pancreas [15], ovary [15, 20, 30], cervix [14, 25, 16, 31], vulva [32], and prostate [33, 29], and from melanoma [21] and leukemia [13] cells. A supra‐additive effect was observed most frequently, but additive or subadditive effects also were demonstrated under some experimental conditions.…”