“…Full limb preparations, intact from the mid-humerus distally, were used to more closely simulate the in vivo mechanical loading environment, as in previous studies. 17,21 The number of cycles to failure under axial compression for the AO-TLS fixation was significantly greater compared with the AP-TS fixation. In cyclic fatigue testing, under axial compression, the axial load was chosen to represent an axial load placed on MC3 during walking (7.52 kN for a weight range of 450-550 kg) 22 and is consistent with previous studies.…”