In vitro binding of bile acids by spinach, kale, brussels sprouts, broccoli, mustard greens, green bell pepper, cabbage and collards

In vitro binding of bile salts by lentil flours, lentil protein concentrates and lentil protein hydrolysates

“…Other studies have reported in vitro binding of bile acids and salts by lupin proteins and their hydrolysates (Yoshie-Stark & Wäsche, 2004), rapeseed proteins and their hydrolysates (Yoshie-Stark, Wada, & Wäsche, 2008), soy proteins (Choi, Adachi, & Utsumi, 2002;Higaki et al, 2006;Kahlon & Woodruff, 2002), wheat gluten (Kahlon & Woodruff, 2002) and enzymatic digests of buckwheat proteins (Ma & Xiong, 2009). In vitro bile acid-binding capacity was also demonstrated for some fruits and legumes (Kahlon, Chapman, & Smith, 2007;Kahlon & Shao, 2004;Kahlon & Smith, 2007a,b;Kahlon, Smith, & Shao, 2005;Kahlon & Woodruff, 2002). However, there are no reports in the literature on the bile acid binding properties of pulses such as lentils.…”

Kale: An excellent source of vitamin C, pro-vitamin A, lutein and glucosinolates

“…In recent years, kale has gained the attention of the scientific community due to its high content of bioactive compounds such as vitamin C, provitamin A, glucosinolates, phenolic antioxidants, dietary fiber, micronutrients (iron, zinc and manganese) and macronutrients (calcium and magnesium) (Ayaz et al, 2006;Cartea, Velasco, Obregón, Padilla, & de Haro, 2008;Khachik, Beecher, & Goli, 1991;Olsen, Aaby, & Borge, 2009). Likewise, in vitro and in vivo studies suggest that kale have a positive impact on the prevention of chronic diseases such as cardiovascular diseases (Kahlon, Chapman, & Smith, 2007;Kim, Yoon, Kwon, Park, & Lee-Kim, 2008;Kural, Küçük, Yücesan, & Örem, 2011) and cancer (Chung, Lee, & Sung, 2002).…”

Acute sulforaphane action exhibits hormonal and metabolic activities in the rat: in vivo and in vitro studies

“…Because all the above presented results were obtained after chronic SF treatment, the unexpected lack of changes in total cholesterol in the present trial (Table 1) seems to be due to a limited time of SF action. The lowering of cholesterol levels reported in long-term experiments was attributed to the absorption site competition (isothiocyanates bind with bile acids reducing fat absorption), reduced synthesis of endogenous cholesterol, as well as to the increase in coprostanol excretion (Kahlon et al 2007;Rodriguez-Cantu et al 2011). Additionally, according to these researchers, the mechanism of anticholesterolemic effects of SF also might have involved its influence on genetic expression of some proteins taking part in the regulation of lipid homeostasis: sterol regulatory element binding protein (SREBP), HMG-CoA reductase (HMGP), fatty acids synthase (FAS), LDL receptors (LDLR), apolipoprotein B (ApoB100) (RodriguezCantu et al 2011).…”