2022
DOI: 10.1590/s2175-97902022e18308
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In vitro assessment for cytotoxicity screening of new antimalarial candidates

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Cited by 8 publications
(4 citation statements)
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“…The nauplii were treated with various concentrations of plant extract for 24 h. The number of motile nauplii was counted to assess the extract’s effectiveness. It is simple to use, reasonably priced and requires very little test material ( Espíndola et al, 2022 ). The assay was performed at a MIC value of 300 μg/ml (all extracts) and FICI value of 150 + 100 μg/ml (extract + cefixime) with serial dilutions.…”
Section: Resultsmentioning
confidence: 99%
“…The nauplii were treated with various concentrations of plant extract for 24 h. The number of motile nauplii was counted to assess the extract’s effectiveness. It is simple to use, reasonably priced and requires very little test material ( Espíndola et al, 2022 ). The assay was performed at a MIC value of 300 μg/ml (all extracts) and FICI value of 150 + 100 μg/ml (extract + cefixime) with serial dilutions.…”
Section: Resultsmentioning
confidence: 99%
“…25 , 48 Other study showed relatively uniform toxicity results of cell lines and normal cell lines. 24 As a result, this study attempted to carry out a cytotoxicity test experiment on MCF-7 cells, which have excellent qualities and are adherent cell types with the monolayer culture method, making them easier to examine than normal cells. 49 …”
Section: Discussionmentioning
confidence: 99%
“…The most popular approach for predicting the hazardous effects of novel drug is in vitro cytotoxicity testing. 24 Cytotoxicity tests can be carried out on many different types of cells, including cancer cells. Cancer cells are unique cells because they have regressed to a stage that is much simpler, more primitive, in contrast to the normal parent, and divide constantly.…”
Section: Introductionmentioning
confidence: 99%
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