In vitro antiplasmodial activity of plants used in Benin in traditional medicine to treat malaria

<i>In vitro</i> evaluation of antiplasmodial activity of extracts of <i>Acanthospermum hispidum</i> dc (Asteraceae) and <i>Ficus thonningii</i> blume (moraceae), two plants used in traditional medicine in the republic of Congo

“…Thereby, the antiplasmodial activity observed in this study might be attributed to one of these compounds since antioxidants, glycosides, coumarins and flavonoids have been reported to possess antimalarial activity (Sriwilaijroen et al, 2010). The IC 50 of Acanthospermum hispidum methanolic extract on the strain 3D7 in our study is lower than that obtained by Bero et al (2009). A possible explanation could be that environmental parameters such as geographic area and nature of the soil may have an influence on the presence and/or quantities of bioactive compounds in plants.…”

“…The aqueous extract was also inactive, confirming previous studies which demonstrated the lack of antimalarial effect of the aqueous extract of this plant. (Bero et al, 2009;Sanon et al, 2003b). In these studies, the dichloromethane extract was 270-276 http://dx.doi.org/10.4314/ajtcam.v10i2.11…”

“…This plant is known for its antiinflammatory, anti-oxydant and hepato-protective properties (Kpemissi et al, 2008). Also, the plant has shown inhibitory effects on Plasmodium falciparum W2 strain in vitro (Bero et al, 2009;Sanon et al, 2003 a , b ). Ficus thonningii is widely used by herbalists and it has been reported to possess analgesic and anti-inflammatory properties (Otimenyin et al, 2004).…”

Antimicrobial activity and phytochemical screening of the fruit pulp of Dialium guineense (Velvet Tamarind) on some microbial isolates

“…D. guineense leaf and bark extracts have been reported by Orji et al, (2012) guineense was also found to inhibit the growth of Plasmodium falciparum, that is, the malaria parasite responsible for the illness (Hermans et al, 2010). It was reported in some literatures that D. guineense leaves and stem bark are used as folklore remedies for the treatment of infections such as diarrhoea, severe cough, bronchitis, wound, stomachaches, malaria fever, jaundice, antiulcer and haemorrhoids (Bero et al, 2009). Lawal et al (2010) reported in their findings that D. guineense is used as antiulcer and as a vitamin supplement among some tribes in the southern part of Nigeria.…”

“…Okwu and Ekeke (2003) reported in their studies that the plant contains saponins which are presumed to add to the cleaning effect of teeth and at the same time prevent caries and plaques on the teeth of the users. D. guineense leaves and stem bark are used as folklore remedies for the treatment of infections such as diarrhoea, severe cough, bronchitis, wound, stomachaches, malaria fever, jaundice, antiulcer and haemorrhoids (Bero et al, 2009). Also, the molluscicidal activity of the fruits and leaves of D. guineense have been reported by Gideon and Ralphael, 2012.…”