In vitro antioxidant properties of rutin

Jian-xiong, Yang; Guo, Juan; Yuan, Jin-Peng

doi:10.1016/j.lwt.2007.06.010

Cited by 618 publications

(388 citation statements)

References 31 publications

Supporting

Mentioning

342

Contrasting

Unclassified

Order By: Relevance

“…The DPPH* method described by Yang et al (2008) was used to evaluate the free radical scavenging activity. A standard curve of DPPH* (A 523nm , slope = 0.0309, y axis crossing point = 0.0019, correlation coefficient r = 0.9996) was used to estimate the DPPH* concentration (µg mL -1 ) in the reaction medium.…”

Section: Free Radical Scavenging Activitymentioning

confidence: 99%

See 1 more Smart Citation

Foliar phenolic compounds of ten wild species of Verbenacea as antioxidants and specific chemomarkers

et al. 2017

View full text Add to dashboard Cite

The family Verbenaceae hosts important species used in traditional medicine of many countries. The taxonomic controversies concerning the specific delimitation of several of its species make it difficult to guarantee the botanical origin of herbal preparations based on species of this family. To contribute to the development of both specific chemomarkers and a quality control tool to authenticate the botanical origin of herbal preparations of Verbenacea species, we determined the foliar HPLC-DAD phenolic profiles and the antioxidant properties of 10 wild species of this family occurring in Mexico. The contents of phenols and flavonoids varied significantly among species. Priva mexicana showed the highest levels of total phenolics (53.4 mg g -1 dry tissue) and Verbena carolina had the highest levels of flavonoids (17.89 mg g -1 dry tissue). Relevant antioxidant properties revealed by antiradical and reducing power were found for the analyzed species. These properties varied significantly in a species-dependent manner. The phenolic compounds accumulated were flavones and phenolic acids. Flavones were the only type of flavonoids found. The results of a cluster analysis showed that the compounds were accumulated in species-specific profiles. The phenolic profiles are proposed as valuable chemomarkers that can become a useful tool for the quality control concerning the botanical origin of herbal medicinal preparations based on the species analyzed. In addition, phenolic profiles could contribute importantly to solve the taxonomic controversies concerning species delimitation in the family Verbenaceae.Keywords: Verbenacea, antioxidant activity, chemomarkers, flavones, phenolic profiles. Compostos fenólicos das folhas de dez especies selvagem de Verbenaceae como antioxidantes e quimiomarcadores específicos ResumoA família Verbenaceae compreende importantes espécies utilizadas na medicina popular de muitos países. As dificuldades taxonômicas relativas à delimitação específica de muitas das suas espécies face difícil a verificar a origem botânico das preparações herbales baseadas nas espécies desta família. Para fazer uma contribuição ao desenvolvimento de indicadores taxonômicos e dum método de controle de qualidade para verificar a origem botânico de preparações herbales das espécies de Verbenaceae, os perfis fenólicos, obtidos pares HPLC-DAD, e as atividades antioxidantes das folhas de 10 espécies selvagens Mexicanas desta família foram determinados. Os conteúdos dos compostos fenólicos totais e dos flavonoides foram significativamente diferentes entre as espécies. Priva mexicana apresentou a maior quantidade de compostos fenólicos totais (53.4 mg g -1 amostra seca) e Verbena carolina apresentou a maior quantidade de flavonoides (17.89 mg g -1 amostra seca). Verifica-se importantes propriedades antioxidantes, como os resultados dos ensaios da capacidade antiradical e do poder redutor indicaram. As propriedades antioxidantes foram significativamente diferentes entre as espécies. Verificou-se que os compostos fe...

show abstract

Section: Free Radical Scavenging Activitymentioning

confidence: 99%

“…The RP values were calculated by using the method described by Yang et al (2008). For each sample, a graph of absorbance at 700 nm vs. increased extract concentrations was constructed to calculate the extract concentration providing 0.5 of absorbance (defined as IC 50 ).…”

Section: Iron Reducing Power (Rp)mentioning

confidence: 99%

Foliar phenolic compounds of ten wild species of Verbenacea as antioxidants and specific chemomarkers

et al. 2017

View full text Add to dashboard Cite

show abstract

“…The reducing power (RP) method reported by Yang, Guo, and Yuan (2008) was used to evaluate the iron reducing power of flower extracts of A. durangensis. Aliquots (1 mL) of each sample were combined with 2.5 mL phosphate buffer (0.2 M, pH 6.6) and 2.5 mL potassium ferricyanide (30 mM) and incubated at 50°C for 20 min.…”

Section: Iron Reducing Powermentioning

confidence: 99%

Flavonoid composition and antioxidant capacity of the edible flowers ofAgave durangensis(Agavaceae)

Barriada-Bernal

Almaraz-Abarca

Delgado-Alvarado

et al. 2013

CyTA - Journal of Food

View full text Add to dashboard Cite

The antioxidant properties and the flavonoid composition of extracts of different hydrophobicity prepared from the entire edible flowers of Agave durangensis were evaluated. Separately, total extracts of tepals and anthers-pollen were analyzed in the same manner. The high performance liquid chromatography with photodiode array detection (HPLC-DAD) analysis revealed a total of eight flavonols (five quercetin glycosides and three kaempferol glycosides), varying in number and concentration in the different extracts. The total extracts of the entire flowers showed the highest flavonoid content (1210.4 µg/g dry extract) and the most complex flavonoid profile (eight compounds). All the extracts showed important antioxidant activity, which was not evidently associated with their flavonoid content. The total extracts of tepals showed the highest antioxidant properties (total antioxidant capacity, free radical scavenging activity, and iron reducing capacity: 30.2 mg ascorbic acid equivalents, EC 50 = 0.074 µg/mL, and IC 50 = 43.28 µg/mL, respectively). The flowers of A. durangensis represent an important source of antioxidant flavonols.Keywords: Agave durangensis; edible flowers; flavonoid profiles; antioxidant capacity; flavonol glycosides Se evaluaron las propiedades antioxidantes y composición fenólica de extractos de diferente hidrofobicidad de flores comestibles enteras de Agave durangensis. Separadamente, se analizaron extractos crudos de tépalos y anteras-polen. El análisis de HPLC-DAD reveló en total ocho flavonoles (cinco glicósidos de quercetina y tres glicósidos de canferol), que variaron en número y concentración en los extractos. Los extractos totales de las flores enteras tuvieron el contenido más alto de flavonoides (1210,4 µg/g extracto seco) y el perfil de flavonoides más complejo (ocho compuestos). Todos los extractos mostraron importante actividad antioxidante, no claramente asociada al contenido de flavonoides. Los extractos crudos de tépalos mostraron las propiedades antioxidantes más altas (capacidad antioxidante total, capacidad bloqueadora de radicales libres, y capacidad reductora de fierro: 30,2 mg de equivalentes de ácido ascórbico, EC 50 = 0,074 µg/mL, e IC 50 = 43,28 µg/mL, respectivamente). Las flores de A. durangensis representan una fuente importante de flavonoles antioxidantes.

show abstract

“…Rutin, being a secondary plant metabolite, is one of the highly valued compounds. Its antifungal, antibacterial, antiinflammatory and anticancer properties and the ability of radical scavenging are most frequently discussed (Biesaga 2011;Guardia et al 2001;Mohd Zainol et al 2009;Navarro-Núñez et al 2008;Wang et al 2011;Yang et al 2008;You et al 2010). These properties require better knowledge of rutin itself, its transformations, and its occurrence and metabolism in plants.…”

Section: Introductionmentioning

confidence: 99%

Does the Plant Matrix Type Have Impact on Rutin Transformation During Its Extraction?

2016

View full text Add to dashboard Cite

Rutin is a flavonoid glycoside found in many plants. It is used as medication and an ingredient of numerous multivitamin preparations and herbal remedies due to its biomedical activity. The present paper deals with transformation processes of rutin during its extraction by methanol, ethanol, and their aqueous mixtures from Aronia melanocarpa (M.) E. and Sambucus nigra L. fruits, Hypericum perforatum L. herb, and Tussilago farfara L. leaves, known as ones of the most riches in rutin plant materials. It has been established that the transformation degree of rutin during its extraction depends not only on extraction time and extractant type but also, to a high degree, on the plant matrix type. Differences in the degree of rutin transformation are influenced by the matrix components in the examined plants. The reported results are particularly important for researchers investigating plant metabolism and looking for new plant components.

show abstract

In vitro antioxidant properties of rutin

Cited by 618 publications

References 31 publications

Foliar phenolic compounds of ten wild species of Verbenacea as antioxidants and specific chemomarkers

Foliar phenolic compounds of ten wild species of Verbenacea as antioxidants and specific chemomarkers

Flavonoid composition and antioxidant capacity of the edible flowers ofAgave durangensis(Agavaceae)

Does the Plant Matrix Type Have Impact on Rutin Transformation During Its Extraction?

Contact Info

Product

Resources

About