In-vitro Antioxidant Potential of Methanolic Extracts of Mirabilis jalapa Linn

Zachariah, Subin Mary; Aleykutty, NA; Viswanad, Vidya; Jacob, Sonu; Prabhakar, Visakh

doi:10.5530/ax.2011.4.13

Cited by 16 publications

(11 citation statements)

References 17 publications

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“…To protect the cells and organ systems of the body against reactive oxygen species, humans have evolved a highly sophisticated and complex antioxidant protection system that functions interactively and synergistically to neutralize free radicals. Thus, antioxidants are capable of stabilizing or deactivating free radicals before they attack cell [ 28 ]. Vitamin E scavenges peroxyl radicals intermediates in lipid peroxidation and is responsible for protecting PUFA present in cell membrane and LDL against lipid peroxidation.…”

Section: Resultsmentioning

confidence: 99%

Abrus precatoriusLeaves: Antioxidant Activity in Food and Biological Systems, pH, and Temperature Stability

Palvai

Mahalingu

Urooj

2014

International Journal of Medicinal Chemistry

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Natural antioxidants present in foods and other biological materials have attracted considerable interest because of their presumed safety and potential nutritional and therapeutic effects. Antioxidant constituents of plant materials act as radical scavengers and convert the radicals to less reactive species. Abrus precatorius (AP) was analyzed for its proximate and phytochemical composition. The leaves were extracted with methanol (ME) and analyzed for antioxidant activity by radical scavenging method, reducing power, ferric reducing capacity, and in vitro inhibition of Fenton's reagent-induced oxidation in oil emulsion and microsomes. In addition, the effect of temperature (100°C, 15, and 30 min) and pH (4.5, 7, and 9) C on the antioxidant activity of ME was investigated. The leaves were rich in total polyphenols, flavonoids, β-carotene, glutathione, α-tocopherol, and ascorbic acid. The ME exhibited varying degree of antioxidant activity in a dose-dependent manner. The AP exhibited more inhibition of oxidation in microsomes (73%) than compared to oil emulsion (21%). Heat treatment resulted in an increase of radical scavenging activity of extract (28% to 43%). At pH 4.5 the extract exhibited more antioxidant activity and stability compared to pH 7 and 9. Data indicates that potential exists for the utilization of Abrus precatorius as a natural antioxidant.

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Section: Resultsmentioning

confidence: 99%

Abrus precatoriusLeaves: Antioxidant Activity in Food and Biological Systems, pH, and Temperature Stability

Palvai

Mahalingu

Urooj

2014

International Journal of Medicinal Chemistry

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“…In food and biological systems, antioxidants are capable of stabilizing or deactivating free radicals before they attack cells [29]. To protect the cells and organ systems of the body against reactive oxygen species, humans have evolved a highly sophisticated and complex antioxidant protection system that functions interactively and synergistically to neutralize free radicals [30]. Vitamin E scavenges peroxyl radicals' intermediates in lipid peroxidation and inhibits oxidation of PUFA present in cell membrane and LDL against lipid peroxidation.…”

Section: Discussionmentioning

confidence: 99%

Canthium parviflorumLeaves: Antioxidant Activity in Food and Biological Systems, pH, and Temperature Stability

Palvai

Mahalingu

Urooj

2014

Chinese Journal of Biology

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Canthium parviflorum leaves were analyzed for their proximate and phytochemical composition. The leaves were extracted with methanol (ME) and analyzed for antioxidant activity by radical scavenging method, reducing power, ferric reducing capacity, and in vitro inhibition of Fenton's reagent induced oxidation in oil emulsion and microsomes. In addition, the effect of high temperature (100 ∘ C, 15 and 30 min) and pH (4.5, 7, and 9) on the antioxidant activity of ME was investigated. The leaves were rich in polyphenols, flavonoids -carotene, glutathione, -tocopherol, and ascorbic acid. The ME exhibited varying degree of antioxidant activity in a dose dependent manner. The RSA was 68%-500 g. Reducing potency was 0.34 and FRAP was 1.377. Canthium exhibited greater inhibition of oxidation in microsomes (73%) than in the oil emulsion (21%). Heat treatment resulted in reduction of radical scavenging activity of extract from 68% to 40%. At pH 4.5 and 7 methanol extract exhibited some percent of antioxidant activity which ranged between 18 and 32%. Data indicates Canthium as a good source of antioxidants and methanol extract exhibited good antioxidant activity.

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“…Mirabilis jalapa L. belongs to the family Nyctaginaceae. It is an annual herbaceous dicotyledon, and has been widely planted as an ornamental flowering plant in different countries . M .…”

Section: Introductionmentioning

confidence: 99%

“…Mirabilis jalapa L. belongs to the family Nyctaginaceae. It is an annual herbaceous dicotyledon, and has been widely planted as an ornamental flowering plant in different countries [1,2]. M. jalapa has a number of characteristics that are extremely important from both fundamental and applied points of view.…”

Section: Introductionmentioning

confidence: 99%

“…jalapa has a number of characteristics that are extremely important from both fundamental and applied points of view. A number of active compounds have been extracted from different organs of M. jalapa , including a ribosome‐inactivating protein associated with antiviral activity , an antifungal phenolic compound , an antimicrobial peptide , a rotenoid showing inhibition of HIV‐1 reverse transcriptase , an antispasmodic compound , and an antioxidant compound . In addition, M. jalapa is a cadmium hyperaccumulator, can strongly endure and effectively degrade hydrocarbons, and can remedy nitrobenzene‐contaminated soils .…”

Section: Introductionmentioning

confidence: 99%

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Structural and functional properties of endosperm starch and flour from dicotyledon Mirabilis jalapa

et al. 2015

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The large endosperm of dicotyledon Mirabilis jalapa may have food and non‐food industrial applications because of its high starch content. In this study, the structural and functional properties of endosperm starch and flour from M. jalapa were investigated. Each seed (about 170.8 mg fresh weight) contained approximately 37.3 mg of dry endosperm. The endosperm contained about 80.1% starch, 1.5% soluble sugar, and 2.3% protein. Starch granules were small (about 1.5 µm) with a regular spherical shape. The starch contained about 56.5% short branch‐chain of amylopectin, 21.3% long branch‐chain of amylopectin, and 22.2% amylose. The starch and flour had CA‐type crystallinity, while the swelling power and water solubility of starch were 15.8 g/g and 17.1%, respectively. The starch had lower gelatinization temperature and higher pasting viscosity than flour. No peak and hot viscosity was observed in pasting profiles of starch and flour. The flour had higher resistance to acid and amylase hydrolysis than starch. Native, gelatinized and retrograded starches had about 16.3%, 86.6%, and 76.6% of rapidly digestible starch, and 46.5%, 2.4%, and 11.8% of resistant starch, respectively. These results were compared with those obtained from monocotyledon rice endosperm starch and flour.

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In-vitro Antioxidant Potential of Methanolic Extracts of Mirabilis jalapa Linn

Cited by 16 publications

References 17 publications

Abrus precatoriusLeaves: Antioxidant Activity in Food and Biological Systems, pH, and Temperature Stability

Abrus precatoriusLeaves: Antioxidant Activity in Food and Biological Systems, pH, and Temperature Stability

Canthium parviflorumLeaves: Antioxidant Activity in Food and Biological Systems, pH, and Temperature Stability

Structural and functional properties of endosperm starch and flour from dicotyledon Mirabilis jalapa

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