In vitro antioxidant, antimicrobial and phytochemical properties of wild banana [Ensete gilletii (E. A. J. DE Wildman)] seeds extract

Michael, Afolayan; Abubakar, S.; Adedayo, Adebiyi; Doyinsola, Idowu; Adebisi, Fagbohun

doi:10.14419/ijac.v2i2.1981

Cited by 7 publications

(5 citation statements)

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“…This condition might contribute to the observed antioxidant properties in an earlier by Odekanyin &Akande, 2019 andAdesegun et al, 2013. Phenols and flavonoids are naturally occurring or dietary antioxidants (Afolayan et al, 2014). Compounds C3 and C4 have absorption bands characteristics of amines suggesting that alkaloids are nitrogen-containing principles (Stuart, 2005).…”

Section: Figure 5 Plots Of Ftir Spectra Of Isolatesmentioning

confidence: 95%

Bioprospective screening and characterization of isolates from Pterocarpus osun leaf and stem bark extracts

Fadeyi,

Afolayan,

Adeniran

2023

Indo. J. Chem. Res.

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Antimicrobial resistance (AMR) ranks among the top 10 world health challenges of the 21st century, predicted that it will cause approximately 10 million deaths in 2050. Therefore, more investigation into identifying new antibiotics from natural sources is inevitable. Compounds from the leaf and stem bark of Pterocarpus osun were isolated using column chromatography, screened for their bioactivities, and characterized using the FTIR spectroscopy method in the ongoing search for novel antimicrobial therapies. The isolates were tested for antibacterial and antifungal activities against eleven pathogenic organisms. The zones of inhibition ranged in diameter from 22 to 30 mm. The minimum inhibitory concentrations were determined. Thin-layer chromatography was used to determine the purity of the compounds, and their retention factor was calculated. This ranged between 0.2424 and 0.8151. The melting points of the compounds were also recorded, as are FTIR spectra ranging from 4000 to 400 cm-1. Some of the peaks recorded are typical of single bond (4000-25000 cm-1), double bond (2000-1500 cm-1) with confirmation in the fingerprint (1500-400 cm-1) region but none in the triple bond (2500-2000 cm-1) region of the spectra. The antimicrobial screening results show that the identified compounds can potentially lead to the discovery of novel antibiotic medications.

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Section: Figure 5 Plots Of Ftir Spectra Of Isolatesmentioning

confidence: 95%

Bioprospective screening and characterization of isolates from Pterocarpus osun leaf and stem bark extracts

Fadeyi,

Afolayan,

Adeniran

2023

Indo. J. Chem. Res.

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“…The radical scavenging activity of each extract was determined using DPPH (2,2diphenyl-1-picrylhydrazyl) assay according to Afolayan et al (2014). The decrease in the absorption of DPPH solution after the addition of an antioxidant was measured at 517 nm.…”

Section: Antioxidant Assaymentioning

confidence: 99%

Comparative Phytochemical and Antioxidant Analysis of the Leaf Extracts of Two Nigerian Medicinal Plants

Olalekan

2023

JSML

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Bridelia ferruginea (Benth., Euphorbiaceae), prominently found in Savannah regions, is commonly used as an ethnomedicine for the treatment of several ailments in many parts of Africa. Piliostigma thonningii (Schum., Fabaceae) is used for various medicinal purposes in African countries with some pharmacological activities established from the crude extracts including antibacterial, antihelminthic, antiinflammatory and antilipidemic activities. In the present study, crude methanolic extract and fractions of B. ferruginea and P. thonningii were examined for their phytochemical constituents and antioxidant activity using standard protocols. Qualitative phytochemical screening of B. ferruginea crude extract revealed the presence of tannins, saponins, phlobatanins, flavonoids, steroids, alkaloids, glycosides, phenols and resins while it tested negative for triterpenoids, carbohydrates, terpenoids and anthraquinones; the quantitative phytochemical analysis showed that it contained 1.5% saponins, 5.3% flavonoids, 1.2% alkaloids and 0.9% phenols. P. thonningii crude extract tested positive for saponins, flavonoids, terpenoids, steroids, alkaloids, and phenols while tannins, phlobatanins, glycosides, triterpenoids, carbohydrates, resins and anthraquinones were absent. It contains 3.2% saponins, 1.6% flavonoids, 1.8% alkaloids, and 0.7% phenols. The concentration of the crude extract required for 50% inhibition of DPPH radical scavenging effect (IC50) is 0.018 and 0.020 mg/ml for B. ferruginea and P. thonningii, respectively, compared to 0.015 mg/ml for vitamin C as a standard antioxidant. Both extracts showed potent inhibition of DPPH radical scavenging activity comparable to that of the Vitamin C standard and would be valuable sources of antioxidant compounds.

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“…In [59], from the results of antioxidant assays in vitro, ethyl acetate was found to have the highest antioxidant activity. e 50% inhibition of DPPH radical scavenging effect (IC 50 ) was recorded as 8.67, 0.64, 0.31, and 0.14 mg/ml for the hexane fraction, ethyl acetate fraction, and ethanol fraction; in [22,60], the water extract has the highest scavenging activity among all extracts. Khan et al [30] revealed that the ethyl acetate fractions of E. gerardiana (root and stem) have significant free radical scavenging potential with values of 2.96 ± 0.39 and 2.73 ± 0.84. e lowest antioxidant activity was found in the n-hexane extract of the plant selected to be equivalent to DPPH [21,61].…”

Section: Antioxidant Activitymentioning

confidence: 99%

The Phytochemical Screening and Antioxidants Potential of Schoenoplectus triqueter L. Palla

Hassan

Akmal

Khan

2020

Journal of Chemistry

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Over the centuries, humans use different types of therapeutic plants to treat several diseases. Cyperaceae family has a significant number of monocotyledon plants, and Schoenoplectus is one of the genera that belong to this family; about forty-nine compounds are isolated. Our current study was evaluated on Schoenoplectus triqueter L. Palla to show the potential of its antioxidants and confirm the phytochemical constituents in this plant species. Fully powdered plant taken for successive extraction process in hot continuous process for Soxhlet was 20 g plant in porous bag manually prepared; the constant temperature provided was 40–50°C. In the maceration extraction method, 30 g plant was taken in a closed jar and the solvent placed for extraction was 300 mL of ethanol; the extract gets filtered and fractioned to different solvents such as water, dichloromethane, ethyl acetate, and n-hexane fraction. Important types of phytochemicals found in this species are alkaloids, proteins, amino acids, flavonoids, phenols, terpenoids, tannins, saponins, and carbohydrates. All the entire extracted fractions which are water, dichloromethane, ethyl acetate, and n-hexane possess noticeable activity at various concentrations of 31.25, 62.5, 125, 250, and 500 µg/mL by the dilution method. The ethyl acetate extract holds greater median inhibitory concentration (IC50 = 3.52 ± 0.01), and water showed IC50 = 3.61 ± 0.01 percent potential as compared to the standard ascorbic acid which possesses IC50 = 2.27 ± 0.01. Their potential may be enhanced or lowered with the purification of extracts which might be useful in biological activities.

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In vitro antioxidant, antimicrobial and phytochemical properties of wild banana [Ensete gilletii (E. A. J. DE Wildman)] seeds extract

Cited by 7 publications

References 1 publication

Bioprospective screening and characterization of isolates from Pterocarpus osun leaf and stem bark extracts

Bioprospective screening and characterization of isolates from Pterocarpus osun leaf and stem bark extracts

Comparative Phytochemical and Antioxidant Analysis of the Leaf Extracts of Two Nigerian Medicinal Plants

The Phytochemical Screening and Antioxidants Potential of Schoenoplectus triqueter L. Palla

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