In Vitro Antioxidant and Antimicrobial Properties of Cucumis Sativus L. Peel Extracts

John, Sheila; Priyadarshini, S.; Monica, Sarah Jane; Sivaraj, C; Arumugam, P

doi:10.7897/2230-8407.0918

Cited by 19 publications

(12 citation statements)

References 16 publications

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“…Namun, berdasarkan penelitian terkini melaporkan bahwa didalam kulit mentimun (Cucumis sativus L.) mengandung senyawa flavonoid sangat tinggi dengan persentase sebesar 71%. Kulit mentimun (Cucumis sativus L.) juga mengandung beberapa senyawa aktif selain flavonoid, yaitu saponin, steroid, dan alkaloid (John et al, 2018) yang diduga dapat berperan untuk menurunkan kolesterol. Berdasarkan latar belakang tersebut kulit mentimun dapat digali lebih lanjut potensinya sehingga dapat bermanfaat untuk meningkatkan kesehatan.…”

Section: Pendahuluanunclassified

LITERATURE REVIEW: CHEMICAL CONTENT AND PHARMACOLOGICAL ACTIVITY OF KERSEN LEAF (Muntingia calabura L.)

Sumarni

Sadino²,

Sumiwi

2022

JFSP

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Kersen (Muntingia calabura L.) is known as a plant that is often used as a tree to absorb air pollution and shade on the roadside. Low economic value and public knowledge about the benefits of cherry as a medicinal and food ingredient is still minimal. The part that can be used as a medicinal ingredient comes from cherry leaves. The purpose of this review article is to provide information related to the chemical content and pharmacological activity of cherry leaves that can treat various diseases. The method used in making this article review is a literature study. The literature sources in this article review were obtained from national journals and international journals published in the last 10 years (2010-2020), which were carried out online through the search engines Google Scholar, Pubmed, and NCBI, using the keywords "Kersen leaves", "Activities cherry leaf”, “Pharmacological activity of Muntingia calabura”, “Chemical content of cherry leaf”, “Muntingia calabura L.”. Journals that enter the inclusion criteria are national and international journals that discuss the pharmacological activity and chemical content of cherry leaves, journals published in the last 10 years (2010-2020), and journals in full text. The chemical constituents contained in cherry leaves are flavonoids, saponins, tannins, and terpenoids. Cherry leaves are scientifically proven to have several pharmacological activities as antidiabetic, antioxidant, antibacterial, anthelmintic, antihyperlipidemic, and anti-inflammatory.

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Section: Pendahuluanunclassified

LITERATURE REVIEW: CHEMICAL CONTENT AND PHARMACOLOGICAL ACTIVITY OF KERSEN LEAF (Muntingia calabura L.)

Sumarni

Sadino²,

Sumiwi

2022

JFSP

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“…Berdasarkan hasil uji kualitatif diatas dapat disimpulkan bahwa pada ekstrak etanol kulit mentimun mengandung senyawa golongan flavonoid, saponin dengan adanya busa yang muncul, alkaloid, dan steroid yang merupakan identifikasi awal kolesterol. Hasil tersebut dapat disesuaikan dengan referensi dari (John et al, 2018) yang menyebutkan bahwa pada kulit mentimun mengandung senyawa metabolit sekunder tersebut serta terdapat juga triterpenoid. Pada penelitian tidak dilakukan uji kualitatif terhada psenyawa triterpenoid karena dalam hal ini fungsi antikolesterol didominasi dengan keberadaan flavonoid, saponin, alkaloid, dan steroid.…”

Section: Hasil Dan Pembahasanunclassified

The Potency of Cucumber (Cucumis Sativus L.) Peel Extract as Anticholesterol

Putri¹,

Anggraini²

2022

JFSP

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The liver has a very important role in the human body. However, these organ tissues are also very susceptible to be tissue damage. Fatty liver disease (steatosis) is a disease caused by high cholesterol. Physically, cholesterol is a yellowish subtance, lumps like wax, and is an arrangement of steroid groups. Non-alcoholic steatohepatitis (NASH) occurs due to excess cholesterol levels in the liver. Liver function can be affected as a result of liver damage. So, a hepatoprotector is needed. The flavonoid content of cucumber skin has potential as an anticholesterol. The purpose of this research is to analyze the ability of the ethanol extract of cucumber peel (Cucumis sativus L.) as a cholesterol lowering agents as indicated by the EC50 value. Maceration extraction method used in this study using 96% ethanol as solvent. Qualitative analysis of ethanolic extract of cucumber peel is known to have flavonoids, steroids, alkaloids as indicated by the appearance of color changes, and saponins which are indicated by the appearance of foam. Lieberman-burchad reagent was used for quantitative analysis of anticholesterol using a UV-Visible spectrophotometer. The analysis was carried out at a maximum wavelength of 665,0 nm with an incubation time of 15 minutes. The concentration variations of the extract used were between 25-150 with a range of 25 ppm. The results showed that the ethanolic extract of cucumber peel could potentially be an anticholesterol with the percentage reduction of 28.50%; 35.45%; 39.59%; 45.82%; 51.24%; and 55.12% at 5 variations of concentration. The EC50 value was achieved at a concentration of 122.04 ppm.

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“…Studies show that cucumber peel possesses bioactive compounds and has good antioxidant and antimicrobial activity 19 .…”

Section: Determination Of Total Flavonoid Concentrations In the Plant Extractsmentioning

confidence: 99%

Untitled

2021

IJPSR

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To analyze In vitro antioxidant activity, total phenolic and flavonoid content of methanolic extract of some cucurbit fruit peels. Methods: Phytochemical screening of extracts was carried out. Aluminium chloride colorimetric method was used to estimate TFC (total flavonoid content), and TPC (total phenolic content) was measured by Folin-ciocalteu method. Two different assays-DPPH free radical scavenging and FRAP were used for the determination of antioxidant activity. Results: The total phenolic content was found to be maximum in Cucumis melo i.e. 42.64 ± 0.85 mg GAE/gdw, and minimum in Cucumis sativus i.e. 8.52 ± 0.74 mg GAE/gdw. Total flavonoid content was found to be maximum in Cucumis melo i.e. 4.71 ± 0.67 mg QE/gdw and minimum in Citrullus lanatus i.e., 0.74 ± 0.31 mgQE/gdw. Results of DPPH Scavenging activity and FRAP assay revealed that all the peel samples had a significant antioxidant potential, where Cucumis melo show the highest antioxidant potential. Conclusions: Results of the present study showed that the selected fruit peels of cucurbit family have bioactive compounds of commercial importance. All the samples showed antioxidant activity, indicating that they can be used as a new source of natural antioxidant compounds and can be used for therapeutic purposes.

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In Vitro Antioxidant and Antimicrobial Properties of Cucumis Sativus L. Peel Extracts

Cited by 19 publications

References 16 publications

LITERATURE REVIEW: CHEMICAL CONTENT AND PHARMACOLOGICAL ACTIVITY OF KERSEN LEAF (Muntingia calabura L.)

LITERATURE REVIEW: CHEMICAL CONTENT AND PHARMACOLOGICAL ACTIVITY OF KERSEN LEAF (Muntingia calabura L.)

The Potency of Cucumber (Cucumis Sativus L.) Peel Extract as Anticholesterol

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