In vitro antioxidant and anti-inflammatory potential of Polyalthia longifolia in rats

Mandal, Shibajee; Rajani, G P; Sharma, Rajesh; Gupta, Nitika

doi:10.4103/0253-7613.93873

Cited by 9 publications

(5 citation statements)

References 5 publications

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“…The absorbance of the chromophore during the diazotization of nitrite with sulfanilamide and subsequent coupling with naphthyl ethylenediamine was measured at 546 nm. A similar procedure was repeated with respective solvent instead of the extract, which served as the control; l -ascorbic acid (5–250 μg/mL) was used as the positive control [ 21 ]. All the tests were performed in triplicate.…”

Section: Methodsmentioning

confidence: 99%

Antifungal and antioxidant activities of organic and aqueous extracts of Annona squamosa Linn. leaves

Kalidindi¹,

Thimmaiah

Jagadeesh³

et al. 2015

Journal of Food and Drug Analysis

100

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An increasing demand for natural additives has shifted the attention from synthetic to natural antioxidants and antifungal agents. This study was carried out to evaluate the antifungal and antioxidant activities of methanol, chloroform, and aqueous extracts of Annona squamosa Linn. leaves. The antifungal activities of all extracts of A. squamosa leaves against five different strains of fungi (Alternaria alternata, Candida albicans, Fusarium solani, Microsporum canis, and Aspergillus niger) were evaluated by the agar well diffusion method and the minimum inhibitory concentration of each extract was assessed by antifungal susceptibility using the broth microdilution method. The antioxidant potential of each extract was determined by free radicals (1,1-diphenyl-2-picrylhydrazyl, nitric oxide, and hydrogen peroxide) scavenging activity and reducing power property of A. squamosa leaves. Both organic and aqueous extracts were found to express dose-dependent inhibition against all tested fungi strains in both agar well diffusion and broth dilution methods. The free radical scavenging activity and reducing power property of all extracts were found to be concentration dependent, with the methanol extract exhibiting higher antioxidant activity than the chloroform extract, which was more effective than the aqueous extract of A. squamosa leaves. Results of phytochemical analysis of extracts showed the presence of glycosides, saponins, tannins, flavonoids, phenols, etc. The results obtained from in vitro studies of antifungal and antioxidant activities clearly suggest that the methanol, chloroform, and aqueous extracts of A. squamosa leaves possess antifungal and antioxidant activity.

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Section: Methodsmentioning

confidence: 99%

Antifungal and antioxidant activities of organic and aqueous extracts of Annona squamosa Linn. leaves

Kalidindi¹,

Thimmaiah

Jagadeesh³

et al. 2015

Journal of Food and Drug Analysis

100

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show abstract

“…These results demonstrate an anti-inflammatory and anti-oxidative activity of the plant extract [3]. In another study, the ethanolic and aqueous extracts of P. longifolia were found to reduce Carrageenan induced edema and inflammation [18]. Hepatoprotective potential of plant has also been demonstrated in an animal study [19,20].…”

Section: Introductionmentioning

confidence: 61%

Polyalthia longifolia Promises to be a Potential Nutraceutical

2015

Med Aromat Plants

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“…Phytochemical investigation of aqueous and ethanolic extracts of Potentilla anserina Linn have revealed the presence of various phytoactive constituents such as alkaloids, saponins, flavonoids, glycosides, tannins, phenolic compounds and steroids. Earlier studies indicate β-sitosterol 1 , flavonoids 4 , phenolic compounds 29 , and tannins 30 may be responsible for anti-inflammatory activity. These plant extracts also contain the similar phyto constituents which was responsible for the activity.…”

Section: Resultsmentioning

confidence: 98%

Anti-Inflammatory Activity of Aqueous And Ethanolic Extracts of Potentilla Anserina Linn

Manisha¹,

Sumanth²

2018

AJPTR

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This study was taken up to assess the aqueous and ethanol extracts of whole plant of Potentilla anserina Linn for anti-inflammatory activity in rats by Formalin induced paw oedema method.Animals were divided into 6 groups of 6 rats. Groups 1 and 2 served as Formalin induced control and standard (Diclofenac 5 mg/Kg, i.p.) respectively. Groups 3 and 4 were treated, orally with aqueous extract of Potentilla anserina Linn of 100 and 400 mg/kg b.w, respectively. Groups 5 and 6 were administered, orally with ethanol extract of Potentilla anserina Linn of 100 and 400 mg/kg b.w, respectively. The paw volume was measured at 0, 1, 2, 3 and 4 hr after Formalin injection.The actual edema volume was calculated. The data was expressed as mean ± S.E.M. The statistical analysis was done by means of ANOVA followed by Dunnett"s post hock test. The aqueous and ethanol extracts of whole plant of Potentilla anserina Linn produced significant reduction of edema in the rats. Ethanol extract of whole plant of Potentilla anserina Linn revealed significant anti-inflammatory activity.

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In vitro antioxidant and anti-inflammatory potential of Polyalthia longifolia in rats

Cited by 9 publications

References 5 publications

Antifungal and antioxidant activities of organic and aqueous extracts of Annona squamosa Linn. leaves

Antifungal and antioxidant activities of organic and aqueous extracts of Annona squamosa Linn. leaves

Polyalthia longifolia Promises to be a Potential Nutraceutical

Anti-Inflammatory Activity of Aqueous And Ethanolic Extracts of Potentilla Anserina Linn

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