In vitro antioxidant activity of Barleria noctiflora L. f.

Yadav, Sangilimuthu Alagar; Raj, Anitha Jabamalai; Ramalingam, Sathishkumar

doi:10.1016/s2221-1691(12)60302-5

Cited by 21 publications

(8 citation statements)

References 34 publications

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“…The reducing ability of compounds was measured according to the reported method . 100 m m of the synthesized compounds (1.0 mL) was mixed with 2.5 mL of phosphate buffer (0.2 m , pH 6.6) and 2.5 mL of potassium ferricyanide (1%).…”

Section: Methodsmentioning

confidence: 99%

PEG Mediated Synthesis and Biological Evaluation of Asymmetrical Pyrazole Curcumin Analogues as Potential Analgesic, Anti‐Inflammatory and Antioxidant Agents

et al. 2014

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The new series of asymmetrical pyrazole curcumin analogues 4a-g were synthesized by using polyethylene glycol (PEG-400) as a green reaction medium and evaluated for their in vivo analgesic and in vitro antioxidant (H2 O2 , DPPH, Ferrous reducing power and Nitric oxide scavenging activity) and anti-inflammatory activities. All the compounds synthesized 4a-g showed the potential to demonstrate analgesic activity as compared to the standard ibuprofen. Among the tested series, compounds 4e and 4b exhibited good hydrogen peroxide scavenging activity as compared to the standard butylated hydroxy toluene (BHT). Compounds 4b, 4d, 4f, and 4g showed good DPPH free radical scavenging activity. Compounds 4b, 4c, 4d, 4e and 4g showed excellent ferrous-reducing power activity, whereas all the compounds showed better nitric oxide scavenging activity than standard ascorbic acid. Additionally, all the synthesized compounds were also screened for their in vitro anti-inflammatory activity. Compounds 4b, 4d, 4f and 4g showed good anti-inflammatory activity as compared to standard diclofenac sodium.

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Section: Methodsmentioning

confidence: 99%

PEG Mediated Synthesis and Biological Evaluation of Asymmetrical Pyrazole Curcumin Analogues as Potential Analgesic, Anti‐Inflammatory and Antioxidant Agents

et al. 2014

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“…After 1 min, 1.5 ml of 20% (w/v) Na 2 CO 3 was added and the volume made up to 10 ml with distilled water. The reaction mixture was incubated at 25°C for 1 h, and the absorbance was measured at 760 nm and compared with a pre-prepared gallic acid calibration curve [12]. The end point of reaction mixture was noted by the formation of blue color.…”

Section: To Estimate Total Phenolic Contents (Tpcs) In Seeds Extractmentioning

confidence: 99%

A Comparative Screening and Evaluation of the Total Phenolics, Flavonoids, and Antioxidant Properties in the Seed Extracts of Punica Granatum L., Psidium Guajava L., and Vitis Vinifera L.

Nelson

Yadav

2019

Asian J Pharm Clin Res

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Objectives: The synthetic antioxidants produce numerous adverse effects to overcome these adverse effects and the use of natural products is the alternative. In this study, the evaluation of total phenolics, flavonoid contents, and antioxidant properties of Punica granatum, Psidium guajava, and Vitis vinifera seed extracts was done. Methods: The total phenolic content was estimated with gallic acid equivalent and the total flavonoid contents were estimated on quercetin equivalent. For the antioxidant properties of selected seed extracts, the 2,2-diphenyl-1-picrylhydrazyl radical scavenging, ferrous reducing power, and hydrogen peroxide radical scavenging assays were followed to find the free radical scavenging ability of the selected seed extracts. Results: The ethyl acetate extract of P. granatum seed contains higher phenolic content (70.25±1.25 μg/ml) and flavonoid content (58.15±1.85 μg/ml) and possesses a high free radical scavenging ability. Based on the inhibitory effects of fruit seeds against synthetic radicals, they can be ranked as P. granatum>P. guajava>V. vinifera. Conclusion: According to overall observations of the study, the pomegranate seed extract contains a higher level of phenolic and flavonoid contents and shows a higher scavenging effect against free radicals among the others seeds. Phytochemical screening showed that the ethyl acetate extract of pomegranate fruit seed possesses more secondary metabolites compared to other seed extracts.

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“…In this present study, the highest anti-H 2 O 2 activity was observed in ethanol extract of B. longiflora (83.4±0.18). Methanol extract of Barleria noctiflora L. root has scavenging activity in high when compared to the leaf [21]. Mohan and Ruba reported that among the five solvents, methanol extract has highly acted to remove the hydroxyl radicals from the sugar and inhibit the reaction when compare with standard [22].…”

Section: Scavenging Of H 2 O 2 H 2 Omentioning

confidence: 99%

In Vitro Evaluation of Antioxidant Potential and Total Phenolic Content of Barleria Longiflora Leaf Extracts

Jothimuniyandi

Jayachitra

2019

Asian J Pharm Clin Res

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Objective: The aim of this present study is to estimate the antioxidant potential found in the leaves of Barleria longiflora that belongs to the family Acanthacea. Methods: Antioxidant activity of six different solvent extracts system of B. longiflora leaves was assayed for 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical activity, scavenging of hydrogen peroxide (H2O2), ferric reducing antioxidant activity, metal chelating ability assay, and total reducing ability. Total phenolic content of the extracts was determined by Folin–Ciocalteu method. Results: The radical scavenging activity was evaluated by DPPH of ethanol extract at concentration of 100 μg/mg was found to be 56.5% followed by methanol 48.4%, whereas maximum scavenging of H2O2 was observed in ethanol 83.4% followed by chloroform 70.8%. Ethanolic extract of B. longiflora leaves showed the highest value in ferric reducing antioxidant power assay 74.8%, metal chelating activity 61.6%, and total reducing ability 0.76±0.02 when compared to the standard ascorbic acid. Conclusion: The results suggest that the antioxidant potential of the ethanol extract has the highest activity in compared to other five extracts of B. longiflora leaves.

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In vitro antioxidant activity of Barleria noctiflora L. f.

Cited by 21 publications

References 34 publications

PEG Mediated Synthesis and Biological Evaluation of Asymmetrical Pyrazole Curcumin Analogues as Potential Analgesic, Anti‐Inflammatory and Antioxidant Agents

PEG Mediated Synthesis and Biological Evaluation of Asymmetrical Pyrazole Curcumin Analogues as Potential Analgesic, Anti‐Inflammatory and Antioxidant Agents

A Comparative Screening and Evaluation of the Total Phenolics, Flavonoids, and Antioxidant Properties in the Seed Extracts of Punica Granatum L., Psidium Guajava L., and Vitis Vinifera L.

In Vitro Evaluation of Antioxidant Potential and Total Phenolic Content of Barleria Longiflora Leaf Extracts

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