In vitro antioxidant activity of Vetiveria zizanioides root extract

Abstract

Free radicals induce numerous diseases by lipid peroxidation and DNA damage. It has been reported that some of the extracts from plants possess antioxidant properties capable of scavenging free radicals in vivo. Vetiveria zizanioides belonging to the family Gramineae, is a densely tufted grass which is widely used as a traditional plant for aromatherapy, to relieve stress, anxiety, nervous tension and insomnia. In this regard, the roots of V. zizanioides was extracted with ethanol and used for the evaluation of various in vitro antioxidant activities such as reducing power ability, superoxide anion radical scavenging activity, deoxyribose degradation assay, total antioxidant capacity, total phenolics and total flavonoid composition. The various antioxidant activities were compared with suitable antioxidants such as butyl hydroxy toluene, ascorbic acid, quercetin, alpha tocopherol, pyrocatechol and curcumin respectively. The generation of free radicals O2-, H2O2, OH and NO were effectively scavenged by the ethanolic extract of V.zizanioides. In all these methods, the extract showed strong antioxidant activity in a dose dependent manner. The results obtained in the present study clearly indicates that V. zizanioides scavenges free radicals, ameliorating damage imposed by oxidative stress in different disease conditions and serve as a potential source of natural antioxidant. The study provides a proof for the ethnomedical claims and reported biological activities. The plant has, therefore, very good therapeutic and antioxidant potential. __________________________________________________________________________________

Nephroprotective activity ofVetiveria zizanioides(L.) Nash supplement in doxorubicin‐induced nephrotoxicity model of Wistar rats

“…Polyphenols contribute directly to the antioxidant activity of medicinal plants (Abuajah et al. 2014; Subhadradevi et al., 2010). The quantification of polyphenols in the aqueous root extract of V. zizanioides by Folin Ciocalteu method substantiated the results of Devprakash and Subburaju (2011), where the fresh aqueous root extracts of V. zizanioides showed a polyphenol content of 15.43 ± 0.31 mg tannic acid equivalents per 100 g dry weight of sample.…”

Fabrication of potable and eco-friendly solar disinfection (sodis) unit and its performance analysis

“…In a study conducted by Das et al, [23], the extracts from the roots of H. indicus inhibited the Ecoli growth, and it was found that the presence of bioactive compounds such as steroids, tannins, saponins, glycosides, flavonoids, and polyphenols might contribute to this antibacterial activity. Work conducted to investigate the effect of roots extracts of V. zizanioides implied that the presence of tannins can be the active compound responsible for antibacterial activity against E-coli bacteria [24].…”

Assessment of Antioxidant Potential and Standardization of Fermented Biomedicine Balarista by High-Performance Thin-Layer Chromatography and Fourier-Transform Infrared Spectroscopy Fingerprint Analysis

“…The root of Sida cordifolia exhibited DPPH radical, reducing power, nitric oxide radical, hydrogen peroxide radical [45] , and ABTS radical [46] scavenging activities. The antioxidant activity of the Balarista can also be supported by the free radical scavenging property of Woodfordia fruticosa [47] , Alpinia galanga [48] , Elettaria cardamomum [49] , Syzygium aromaticum [50] , Ipomoea digitata [51] , Paederia foetida [52] , Ricinus communis [53] , Tribulus terrestris [54] , Vetiveria zizanioides [55] .…”