In vitro antifungal resistance profile of Candida strains isolated from Saudi women suffering from vulvovaginitis

Yassin, Mohamed Taha; Mostafa, Ashraf Abdel‐Fattah; Al-Askar, Abdulaziz A.; Bdeer, Rashad

doi:10.1186/s40001-019-0399-0

Cited by 70 publications

(82 citation statements)

References 38 publications

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“…After the application of the eligibility criteria, 39 studies were finally included [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 ], one (2.6%) of which was described as “rapid” [ 42 ] and two (5.1%) as “scoping” systematic reviews [ 30 , 50 ]. Thirteen (33%) of them also undertook a meta-analysis [ 14 , 16 , 18 , 19 , 24 , 25 , 27 , 36 , 38 , 40 , 48 ,…”

Section: Resultsmentioning

confidence: 99%

“…Thirteen (33%) of them also undertook a meta-analysis [ 14 , 16 , 18 , 19 , 24 , 25 , 27 , 36 , 38 , 40 , 48 , 49 , 52 ]. Twenty-nine (74%) reviews evaluated quality of individual studies [ 14 , 15 , 16 , 19 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 37 , 41 , 42 , 43 , 44 , 46 , 47 , 48 , 51 , 52 ], with one of them doing so, in a subjective manner, without utilizing any assessment tool [ 42 ]. Among the eligible systematic reviews’ last search dates, the most recent one took place on 8 July 2020.…”

Section: Resultsmentioning

confidence: 99%

“…Among the eligible systematic reviews’ last search dates, the most recent one took place on 8 July 2020. Nineteen studies (48.7%) contained only confirmed women for SARS-CoV-2 [ 14 , 15 , 16 , 18 , 19 , 20 , 23 , 24 , 27 , 28 , 36 , 37 , 38 , 43 , 45 , 46 , 48 , 49 , 52 ] (2 studies used the term “laboratory confirmed COVID-19” [ 14 , 19 ], 6 studies the term “confirmed COVID-19” [ 16 , 18 , 28 , 38 , 48 , 49 ], 10 studies the term “PCR-confirmed” [ 15 , 20 , 23 , 24 , 27 , 36 , 37 , 43 , 46 , 52 ] and one study the term “COVID-19 positive” [ 45 ]), fourteen (35.9%) included either PCR-confirmed or women whose diagnosis of COVID-19 was based on clinical and/or radiological findings, without further laboratory confirmation [ 17 , 21 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 40 , 44 ,…”

Section: Resultsmentioning

confidence: 99%

“…Twelve reviews (30.8%) were found to be of “very low quality” [ 16 , 17 , 18 , 20 , 28 , 33 , 34 , 38 , 39 , 42 , 50 , 51 ], 11 (28.2%) of “low quality” [ 14 , 15 , 19 , 21 , 22 , 23 , 29 , 30 , 37 , 41 , 44 ], 13 (33.3%) of “moderate” [ 24 , 26 , 31 , 32 , 35 , 36 , 40 , 43 , 45 , 46 , 47 , 49 , 52 ], and three (7.7%) of “high quality” [ 25 , 27 , 48 ] ( Supplementary Table S2 ).…”

Section: Resultsmentioning

confidence: 99%

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Maternal and Neonatal Characteristics and Outcomes of COVID-19 in Pregnancy: An Overview of Systematic Reviews

Papapanou

Papaioannou

Petta

et al. 2021

IJERPH

125

109

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(1) Background: A considerable number of systematic reviews, with substantial heterogeneity regarding their methods and included populations, on the impact of COVID-19 on infected pregnant women and their neonates, has emerged. The aim was to describe the obstetric-perinatal and neonatal outcome of infected pregnant women and their newborns during the COVID-19 pandemic; (2) Methods: Three bibliographical databases were searched (last search: 10 September 2020). Quality assessment was performed using the AMSTAR-2 tool. Primary outcomes included mode of delivery, preterm delivery/labor, premature rupture of membranes (PROM/pPROM) and abortions/miscarriages. Outcomes were mainly presented as ranges. A separate analysis, including only moderate and high-quality systematic reviews, was also conducted. The protocol was registered with PROSPERO (CRD42020214447); (3) Results: Thirty-nine reviews were analyzed. Reported rates, regarding both preterm and term gestations, varied between 52.3 and 95.8% for cesarean sections; 4.2–44.7% for vaginal deliveries; 14.3–63.8% specifically for preterm deliveries and 22.7–32.2% for preterm labor; 5.3–12.7% for PROM and 6.4–16.1% for pPROM. Maternal anxiety for potential fetal infection contributed to abortion decisions, while SARS-CoV-2-related miscarriages could not be excluded. Maternal ICU admission and mechanical ventilation rates were 3–28.5% and 1.4–12%, respectively. Maternal mortality rate was <2%, while stillbirth, neonatal ICU admission and mortality rates were <2.5%, 3.1–76.9% and <3%, respectively. Neonatal PCR positivity rates ranged between 1.6% and 10%. After accounting for quality of studies, ranges of our primary outcomes remained almost unchanged, while among our secondary outcomes, maternal ICU admission (3–10%) and mechanical ventilation rates (1.4–5.5%) were found to be relatively lower; (4) Conclusions: Increased rates of cesarean sections and preterm birth rates were found, with iatrogenic reasons potentially involved. In cases of symptomatic women with confirmed infection, high maternal and neonatal ICU admission rates should raise some concerns. The probability of vertical transmission cannot be excluded. Further original studies on women from all trimesters are warranted.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Maternal and Neonatal Characteristics and Outcomes of COVID-19 in Pregnancy: An Overview of Systematic Reviews

Papapanou

Papaioannou

Petta

et al. 2021

IJERPH

125

109

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“…Candida albicans , a human commensal and an opportunistic pathogen is the most commonly isolated species. While it is a normal part of mucosal microbiota found in the gastrointestinal, respiratory, and genitourinary tracts, Candida albicans is frequently responsible for nosocomial candidemia [ 120 , 121 , 122 ].…”

Section: Antimicrobial Range Of Essential Oils—magnetite Nanosystementioning

confidence: 99%

Magnetite Nanoparticles and Essential Oils Systems for Advanced Antibacterial Therapies

Mihai

Chircov

Grumezescu

et al. 2020

IJMS

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Essential oils (EOs) have attracted considerable interest in the past few years, with increasing evidence of their antibacterial, antiviral, antifungal, and insecticidal effects. However, as they are highly volatile, the administration of EOs to achieve the desired effects is challenging. Therefore, nanotechnology-based strategies for developing nanoscaled carriers for their efficient delivery might offer potential solutions. Owing to their biocompatibility, biodegradability, low toxicity, ability to target a tissue specifically, and primary structures that allow for the attachment of various therapeutics, magnetite nanoparticles (MNPs) are an example of such nanocarriers that could be used for the efficient delivery of EOs for antimicrobial therapies. The aim of this paper is to provide an overview of the use of EOs as antibacterial agents when coupled with magnetite nanoparticles (NPs), emphasizing the synthesis, properties and functionalization of such NPs to enhance their efficiency. In this manner, systems comprising EOs and MNPs could offer potential solutions that could overcome the challenges associated with biofilm formation on prosthetic devices and antibiotic-resistant bacteria by ensuring a controlled and sustained release of the antibacterial agents.

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Intraocular pressure responses to walking with surgical and FFP2/N95 face masks in primary open-angle glaucoma patients

Janićijević

Redondo

Jiménez

et al. 2021

Graefes Arch Clin Exp Ophthalmol

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Purpose The use of face mask is globally recommended as a preventive measure against COVID-19. However, the intraocular pressure (IOP) changes caused by face masks remain unknown. The objective of this study was to assess the impact of wearing surgical and FFP2/N95 face masks during a 400-m walking protocol on IOP in primary open-angle glaucoma (POAG) patients. Methods Thirteen subjects diagnosed of POAG (21 eyes) were enrolled in this study. IOP was measured at baseline, during the 400-m walking protocol and after 5 min of passive recovery while POAG patients wore a surgical mask, FFP2/N95 mask and no mask in randomized order. From the 21 POAG eyes, we analyzed the IOP changes caused by physical exercise with two face masks and without wearing any face mask. Results At rest (baseline and recovery measurements), the use of the different face masks did not affect IOP levels (mean differences ranging from 0.1 to 0.6 mmHg). During physical activity, wearing an FFP2/N95 mask caused a small (mean differences ranging from 1 to 2 mmHg), but statistically significant, IOP rise in comparison to both the surgical mask and control conditions (Cohen’s d = 0.63 and 0.83, respectively). Conclusion Face masks must be used to minimize the risk of SARS-CoV-2 transmission, and POAG patients can safely use FFP2/N95 and surgical masks at rest. However, due to the IOP rise observed while walking with the FFP2/N95 mask, when possible, POAG patients should prioritized the use of surgical masks during physical activity.

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In vitro antifungal resistance profile of Candida strains isolated from Saudi women suffering from vulvovaginitis

Cited by 70 publications

References 38 publications

Maternal and Neonatal Characteristics and Outcomes of COVID-19 in Pregnancy: An Overview of Systematic Reviews

Maternal and Neonatal Characteristics and Outcomes of COVID-19 in Pregnancy: An Overview of Systematic Reviews

Magnetite Nanoparticles and Essential Oils Systems for Advanced Antibacterial Therapies

Intraocular pressure responses to walking with surgical and FFP2/N95 face masks in primary open-angle glaucoma patients

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