In vitro antifungal activity of indirubin isolated from a South Indian ethnomedicinal plant Wrightia tinctoria R. Br.

An ancient plant Lawsonia inermis (henna): Determination of in vitro antifungal activity against dermatophytes species

“…Since early times, a majority of the medicinal preparations were of plant origin, either in the simple form of raw plant material or in the more refined forms of the crude extract, mixtures. This resulted from the recognition of the value of traditional medicinal practices; these traditional medical practices have since been adopted in many countries as an integral part of their culture [25]. Table 2 The number and percentages of dermatophytes species according to the type of tinea.…”

“…L. inermis exhibited absolute toxicity against ringworm causing fungal species, such as M. gypseum and T. mentagrophytes. The ethanol extract of the whole plant of L. inermis showed antifungal activity against T. mantagrophytes, Candida albicans, C. neoformans, Aspergillus niger and M. canis [4,7,16,20,25,31,32,36]. Bark extract of L. inermis showed fungitoxic effect against ringworm fungi [35].…”

Documentation and quantitative analysis of the local knowledge on medicinal plants among traditional Siddha healers in Virudhunagar district of Tamil Nadu, India

“…Acalypha indica had shown a wide array of antibiotic effect for bacteria (Somchit et al, 2010), fungi (Ponnusamy et al, 2010), Mycobacterium tuberculosis (Gupta et al, 2010b) and helminthes (Chengaiah et al, 2009). However, there were no clinical evidences on the efficacy of this herb to treat skin infections.…”

“…The plants such as Eclipta prostrata, Acacia sinuata, Lawsonia inermis, Santalum album, Hibiscus rosa-sinensis, Sesbania sesban, Senna auriculata, Hemidesmus indicus, Phyla nodiflora and Phyllanthus emblica are also used by the herbal cosmetics industries throughout India (Gupta et al, 2010a). Some anthroquinone aglycones from Senna alata (Wuthi-Udomlert et al, 2010), indurubin from Wrightia tinctoria (Ponnusamy et al, 2010), rhein from Cassia fistula (Duraipandiyan and Ignacimuthu, 2007) and swertiamarin from Enicostemma axillere (Soni and Gupta, 2009) were reported as antibiotics.…”

In vitro and in vivo antifungal activity, liver profile test, and mutagenic activity of five plants used in traditional Mexican medicine

“…The anti-dermatophyte in vitro activities of several herbal extracts have been examined in previous reports (Machado et al, 2009;Ponnusamy et al, 2010;Sule et al, 2012). However, the extracts displayed much weaker activity than the commonly used synthetic anti-dermatophyte drugs, and only a small number of these extracts have been evaluated in experimental models, which limits the use of these extracts as potential therapeutic agents (Evron et al, 1990;Mikaeili et al, 2012).…”