In vitro antifungal activity against Candida species of Sri Lankan orthodox black tea (Camellia sinensis L.) belonging to different agro-climatic elevations

Anti-Acetylcholinesterase Activity of Commercially Important Ceylon Black Tea (Camellia sinensis L.) Grades Belonging to Different Elevations: Potential Natural Product for Type 3 Diabetes Management?

“…However, in most of the above stated studies collection of authenticated tea samples (mostly market collected tea samples), sample preparation protocols and sample extraction protocols are different from the present study. Further, none of the studies clearly specified the origin, grade, manufacturing technique, particle size, and elevation of the tea samples used [20][21][22][23] although pharmacological activities and the sensory properties of tea are shown to be varied with the above-mentioned factors [18,[26][27][28][29][30]. Thus, we hope comparison of results of the present study with previously reported studies is not that meaningful and appropriate.…”

“…Black tea samples from three different elevations in the country namely low grown, mid grown and high grown were studied as these are the three main tea growing regions in Sri Lanka [18]. Further, biological activities and sensory properties of Ceylon tea are reported to vary significantly depending on the tea growing elevation in the country [18,[27][28]30].…”

“…Apart from anti-diabetic properties, several other beneficial pharmacological properties namely anti-bacterial [27], anti-fungal [28] thrombolytic [40], anti-hyaluronidase [30], anti-tyrosinase [41], sun screening [42], cholesterol micellization inhibitory [43], pancreatic lipase inhibitory [43], cholesterol esterase inhibitory [43] activities in vitro and diuretic [44], anti-diarrheal [45], antiinflammatory [46], gastro protective [47], gastric ulcer healing [48], anti-pyretic [49], and antinociceptive [50] activities in vivo were previously shown by us for some of the Ceylon black tea samples tested in the present study. Thus, interestingly selected Ceylon black tea might be a multifaceted natural product for prevention and management of wide range of diseases including Alzheimer's disease.…”

“…However, Ceylon tea including Ceylon black tea is not reported for AChE inhibitory activity to date. On the other hand, in most of the studies on health benefits of tea in the world, the origin, grade, nature (blend or factory fresh), manufacturing technique, particle size, and elevation of the tea samples used are not specified [20][21][22][23] although pharmacological potential of tea has shown to be varied with the above-mentioned factors [26][27][28][29][30]. In this study we report AChE inhibitory activity of commercially important and origin, grade, nature, manufacturing technique and particle size known three commercially important Ceylon black tea grades belonging to different elevations.…”

Antimicrobial and Alpha-Amylase Inhibitory Activities of Organic Extracts of Selected Sri Lankan Bryophytes

“…Gentamicin (20 μ g/disc) was used as the positive control for bacteria, while 1 : 1 mixture of ketoconazole and itraconazole (10 μ g/disc from each) was used for pathogenic fungus. The growth inhibitions were visually examined by comparing with the positive control [ 16 – 19 ].…”