In vitro antibacterial properties of MoO3/SiO2/Ag2O nanocomposite coating prepared by double cathode glow discharge technique

Abstract

To obtain a self-disinfecting surface to combat nosocomial infections, in situ synthesis of the MoO 3-SiO 2-Ag 2 O nanocomposite antibacterial coating was prepared onto Ti-6Al-4V substrate via a double cathode glow discharge technique conducted in a Ar + O 2 gas mixture. The phase composition, microstructure and chemical structure of the as-prepared coating were systematically characterized by means of a series of microscopic examination methods. The microstructure of the coating exhibited an amorphous/nanocrystalline architecture, and both the MoO 3 and Ag 2 O crystallites were evenly embedded in an amorphous SiO 2 matrix. Photocatalytic activities of the coating were evaluated by photodegradation of rhodamine B (RhB) dye. The results showed that the introduction of Ag 2 O enhanced photocatalytic activity of the MoO 3-SiO 2 nanocomposite coating. In vitro antibacterial activity of the MoO 3-SiO 2-Ag 2 O coating against Gram-negative bacteria, Gram-positive bacteria and fungi were investigated and compared with that of the MoO 3-SiO 2 coating under both dark and visible light conditions. The MoO 3-SiO 2-Ag 2 O coating possessed higher bactericidal activities than the MoO 3-SiO 2 coating, due to the combined effects of surface hydrophobicity, the release of Ag + ions, surface acidic reaction and photocatalytic activity.

Nanoarchitectonics of Hydroxyapatite/Molybdenum Trioxide/Graphene Oxide Composite for Efficient Antibacterial Activity

“…On the other hand, a wide range of diseases is initiated by bacteria contagions. World Health Organization stated that germicidal infection is the fourth leading cause of disease in developed countries [15]. Adding, around 1.4 million persons suffer from pathogenic infection in healthcare surroundings [15].…”

“…World Health Organization stated that germicidal infection is the fourth leading cause of disease in developed countries [15]. Adding, around 1.4 million persons suffer from pathogenic infection in healthcare surroundings [15]. Some researchers have examined Molybdenum trioxide-based materials as antibacterial agents, finding that the germicidal behavior of MoO 3 is initiating from the creation of oxonium ions (H 3 O + ) [15].…”

“…Adding, around 1.4 million persons suffer from pathogenic infection in healthcare surroundings [15]. Some researchers have examined Molybdenum trioxide-based materials as antibacterial agents, finding that the germicidal behavior of MoO 3 is initiating from the creation of oxonium ions (H 3 O + ) [15]. Thus, these species of ions disturbing the pH equilibrium and the cellular enzymatic transport systems, also failing in bacterial proliferation [15].…”

Sputter-Deposited Cr–Ag Films for Environmental Antimicrobial Applications

“…It is of crucial importance to impede the spread of unwanted bacteria and viruses in clinical and environmental circumstances. Over 20 metallic elements have been studied for antimicrobial property [5,6], in which Ag, Cu, Zn, etc are demonstrated to possess good microcidal activity [1,[6][7][8][9]. In particular, silver as a historic and effective antimicrobial agent has a wide spectrum against many drug-resistant bacteria [10] and a fairly good compatibility with mammalian cells.…”

Mechanical, Electrochemical, and Osteoblastic Properties of Gradient Tantalum Coatings on Ti6Al4V Prepared by Plasma Alloying Technique

“…Furthermore, due to the lack of sufficient diffusion between the coating and substrate, the interfacial strength of coatings prepared by the above-mentioned methods still needs to be improved by an additional annealing treatment. Plasma alloying technique has been used to prepare biocompatibility and antibacterial coatings in recent decades [19][20][21]. During the alloying process, the interdiffusion of alloy elements at high temperature is responsible for the continuous and gradient distribution of elements from the deposition layer and substrate, which eventually results in a high interfacial strength of the coating.…”