In Vitro Antibacterial and Antifungal Activities of Aqueous and Ethanolic Leaf Extracts of Acacia Auriculiformis

Rao, Ashwin; Shobha, KL; Shetty, Manjunath; Pai, K. Sreedhara Ranganath

doi:10.22159/ajpcr.2018.v11i12.28853

Cited by 5 publications

(3 citation statements)

References 7 publications

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“…These findings suggest that the ethanolic extraction method yielded extracts with broad-spectrum antibacterial activity, effectively targeting a diverse range of bacterial species. Additionally, the data demonstrated significant inhibition of these tested microorganisms by the ethanolic leaf extract (Shobha et al, 2018).…”

Section: Findings and Discussion Antimicrobial Activity Of A Occident...mentioning

confidence: 79%

Utilizing Anacardium occidentale Leaves Extract as an Alternative to Conventional Antibiotics Against Antimicrobial-Resistant Microorganisms

Sulong,

Hazman,

Mansor

et al. 2024

jhasib

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Antimicrobial resistance (AMR) is a critical global health crisis that compromises the efficacy of conventional antibiotics and increases the need for alternative therapeutic strategies. This study investigates the potential of A. occidentale leaf extracts as a natural replacement for conventional antibiotics, particularly against antibiotic-resistant bacteria. Extracts from young and mature leaves were prepared using aqueous and ethanolic methods and evaluated for their antimicrobial properties using the Kirby-Bauer disk diffusion method. The results showed that ethanolic extracts from young leaves exhibited a broad spectrum of antibacterial activity and effectively inhibited 17 bacterial strains, including S. typhimurium and S. aureus, with inhibition zones of up to 35.58 mm. This indicates that the young leaves are rich in bioactive compounds such as flavonoids, phenolic acids and terpenoids, which are known for their strong antimicrobial properties. In contrast, ethanolic extracts of mature leaves showed more specific antibacterial activity, particularly against S. aureus and methicillin-resistant S. aureus (MRSA), with zones of inhibition of 17.15 mm and 15.70 mm, respectively. These results suggest that mature leaves may contain unique bioactive compounds that are effective against specific pathogens, highlighting their potential for targeted antimicrobial therapies. This study highlights the importance of A. occidentale as a source of natural antimicrobial agents and emphasises the need to adhere to the principles of Islamic Sharia law during extraction. Given the ongoing threat of antibiotic resistance, the results support further research into the therapeutic applications of plant-derived compounds that combine traditional medical knowledge with modern scientific approaches to combat antibiotic-resistant infections.

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Section: Findings and Discussion Antimicrobial Activity Of A Occident...mentioning

confidence: 79%

Utilizing Anacardium occidentale Leaves Extract as an Alternative to Conventional Antibiotics Against Antimicrobial-Resistant Microorganisms

Sulong,

Hazman,

Mansor

et al. 2024

jhasib

View full text Add to dashboard Cite

show abstract

“…Several plants offer as a new source of antibacterial, antifungal, and antiviral with significant activity against infective microorganisms [8]. Several studies related to the use of plants as antimicrobial agents have been carried out, such as the antibacterial and antifungal activity of the ethanol extract of Acacia auriculiformis leaves [9] and studies conducted using barks of Casuarina equisetifolia showed antibacterial activity against E. coli with maximum inhibition zone 23±0.24 mm at a 100 μg concentration [10].…”

Section: Resultsmentioning

confidence: 99%

Antibacterial Activity of Fresh Palm Fruit (Veitichia merillii) against Propionibacterium acnes Bacteria

Andini,

Juniawan,

Irawan

et al. 2023

AJOB

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Antibiotics or antimicrobials are a group of compounds, both natural, semi-synthetic and synthetic, which have the property of killing or inhibiting the growth of bacteria. The infection studied in this research is a skin infection caused by the bacterium Propionibacterium acnes. Several studies have examined the bioactivity potential of palm plant parts such as the toxicity of palm fruit seeds to Artemia salina larvae. but there is no data regarding the antimicrobial potential of the palm fruit itself. The novelty of this study lies in the maturity phase of the simplicia or fruit used, namely ripe, half-riped and unripe palm fruit and the type of pathogenic bacteria that was inhibited, namely Propionibacterium acnes which was carried out in vitro. The purpose of this study was to determine whether palm fruit has antimicrobial activity against Propionibacterium acnes and the ripening phase of the fruit has the highest antimicrobial activity. The research method used is laboratory experimental research. Antibacterial activity test of palm fruit against bacteria was carried out in vitro using the disc method with an activity indicator in the form of the diameter of the inhibition zone. Fresh palm fruit (Veitichia merillii) juice has antibacterial activity against the acne-causing bacteria Propionibacterium acnes, but has a different level of inhibition when viewed from the level of maturity. The highest antibacterial activity based on research results was observed at the ripeness level (yellow/orange color) which was indicated by the width of the inhibition zone of 23.9 mm.

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“…The tree contains large amounts of arabinose, rhamnose, galactose, glucuronic acid, and methyl glucuronic acid. 3 The plant has reportedly demonstrated a range of pharmacological properties, including antioxidant & anti-inflammatory 4 , antibacterial & antifungal, 5 antimalarial, 6 antifilarial, 7 cestocidal, 8 antimutagenic & chemopreventive, 9 spermicidal, 10 hepatoprotective, 11 wound-healing, 12 and antidiabetic action. 13 Auriculoside, a flavan glycoside isolated from A. auriculiformis, was found to have central nervous system depressive action.…”

Section: Introductionmentioning

confidence: 99%

Formulation and Evaluation of Antimicrobial Ointment from Acacia auriculiformis Leaves Extract

Telrandhe,

Galat,

Chavan

et al. 2022

IJDDT

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The current experiment aims to create and test an ointment with an ethanolic extract from Acacia auriculiformis for antimicrobial action. The soxhalation procedure was used to create the ethanolic extract. After producing the ointment base, five batches of ointments were created by incorporating the extract into the base. Physical and chemical properties of each formulation, including color, flavor, pH, spreadability, consistency, solubility, and washability, were assessed. The formulation’s stability at different temperature conditions was also assessed, and the results show that neither its irritancy nor its spreadability has changed. F5 was discovered to be the ideal formulation among the ointment batches. It has a larger zone of inhibition over both gram-positive and gram-negative bacteria.

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In Vitro Antibacterial and Antifungal Activities of Aqueous and Ethanolic Leaf Extracts of Acacia Auriculiformis

Cited by 5 publications

References 7 publications

Utilizing Anacardium occidentale Leaves Extract as an Alternative to Conventional Antibiotics Against Antimicrobial-Resistant Microorganisms

Utilizing Anacardium occidentale Leaves Extract as an Alternative to Conventional Antibiotics Against Antimicrobial-Resistant Microorganisms

Antibacterial Activity of Fresh Palm Fruit (Veitichia merillii) against Propionibacterium acnes Bacteria

Formulation and Evaluation of Antimicrobial Ointment from Acacia auriculiformis Leaves Extract

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