In vitro Antibacterial Activity of n-Hexane Fraction of Methanolic Extract of Plumeria rubra L. (Apocynaceae) Stem Bark

Dey, Abhijit; Das, Trisha; Mukherjee, Souryadeep

doi:10.3923/jps.2011.135.142

Cited by 16 publications

(3 citation statements)

References 22 publications

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“…Medicago growth conditions and inoculation: Seeds of wild-type M. truncatula (Jemalong A17) were scarified with an 8min treatment with concentrated sulfuric acid, surface-sterilized with a2 .4 % (w/v)c alcium hypochlorite solution for 1min, synchronized by imbibition at 4 8Cf or 48 h, and germinated by incubating at room temperature overnight as previously described. [46] The germinated seedlings were grown on modified Fahräeus medium plates inside ag rowth chamber with a1 6h,2 28Cd ay and 8h,2 48Cn ight cycle and 150 to 200 mmol m À2 s À1 light intensity.P lant roots were inoculated with Sinorhizobium meliloti 1021 (wild-type) cultures on the indicated days. After bacterial inoculation, the plants were transferred to freshly poured low-nitrogen Fahräeus medium plates supplemented with the indicated AHL.…”

Section: Methodsmentioning

confidence: 99%

Interkingdom Responses to Bacterial Quorum Sensing Signals Regulate Frequency and Rate of Nodulation in Legume–Rhizobia Symbiosis

et al. 2016

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Density-dependent phenotypic switching in bacteria, the phenomenon of quorum sensing (QS), is instrumental in many pathogenic and mutualistic behaviors. In many Gram-negative bacteria, QS is regulated by N-acylated-l-homoserine lactones (AHLs). Synthetic analogues of these AHLs hold significant promise for regulating QS at the host-symbiont interface. Regulation depends on refined temporal and spatial models of quorums under native conditions. Critical to this is an understanding of how the presence of these signals may affect a prospective host. We screened a library of AHL analogues for their ability to regulate the legume-rhizobia mutualistic symbiosis (nodulation) between Medicago truncatula and Sinorhizobium meliloti. Using an established QS-reporter line of S. meliloti and nodulation assays with wild-type bacteria, we identified compounds capable of increasing either the rate of nodule formation or total nodule number. Most importantly, we identified compounds with activity exclusive to either host or pathogen, underscoring the potential to generate QS modulators selective to bacteria with limited effects on a prospective host.

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Section: Methodsmentioning

confidence: 99%

Interkingdom Responses to Bacterial Quorum Sensing Signals Regulate Frequency and Rate of Nodulation in Legume–Rhizobia Symbiosis

et al. 2016

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“…ex Royle extracts, were gastrointestinal diseases, followed by skeletomuscular and nervous disorders; other common diseases include fever, headache, wounds, renal/urinary, gynecological, bone disorders, psychiatric disorders, respiratory and liver complaints, cardiovascular and cancer. Numerous mediators have provided detail about the pharmacokinetic importance of plants used in gastrointestinal messes [61][62][63][64][65][66][67][68][69][70][71][72]. The leaves and roots of Paeonia emodi Wall.…”

Section: Ethnopharmacologymentioning

confidence: 99%

A comprehensive review on traditional uses, phytochemistry and pharmacological properties of Paeonia emodi Wall. ex Royle: current landscape and future perspectives

et al. 2023

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Paeoniaemodi Wall. ex Royle is commonly known as Himalayan paeony has great importance as a food and medicine. The practice of Paeoniaemodi Wall. ex Royle is very ancient and it is conventionally used for a wide range of illnesses in the folk system of medicine because of its wide beneficial phytochemical profile. The main purpose of the current review was the synthesis of recent data on botany, ethnopharmacology, phytochemistry and potential pharmacological mechanisms of action of Paeoniaemodi Wall. ex Royle, thus offering new prospects for the development of new adjuvant natural therapies. Using scientific databases such as PubMed/MedLine, Scopus, Web of Science, ScienceDirect, Google Scholar, Springer, and Wiley, a comprehensive literature search was performed for Paeoniaemodi Wall. ex Royle. For searching, we used the next MeSH terms: “Biological Product/isolation and purification”, “Biological Products/pharmacology”, “Drug Discovery/methods”, “Ethnopharmacology, Medicine”, “Traditional/methods”, “Paeonia/chemistry”, “Plant Extracts/pharmacology”, “Phytochemicals/chemistry”, “Phytochemicals/pharmacology”, “Plants, Medicinal”. The results of the most recent studies were analyzed and the most important data were summarized in tables and figures. Phytochemical research of Paeoniaemodi Wall. ex Royle has led to the isolation of triterpenes, monoterpenes, phenolic acids, fatty acids, organic compounds, steroids, free radicals and some other classes of primary metabolites. In addition, diverse pharmacological activities like antibacterial, antifungal, anticoagulant, airway relaxant lipoxygenase and beta-glucuronidase inhibiting activity, radical scavenging activity, phytotoxic and insecticidal activities have been reported for Paeoniaemodi Wall. ex Royle. Different bioactive compounds of Paeoniaemodi Wall. ex Royle has proven their therapeutic potential in modern pharmacological and biomedical research to cure numerous gastrointestinal and nervous disorders. In future, further in vitro and in vivo therapeutic studies are required to identify new mechanisms of action, pharmacokinetics studies, and new pharmaceutical formulations for target transport and possible interaction with allopathic drugs. Also, new research regarding quality evaluation, toxicity and safety data in humans is needed.

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“…[36] like all oleoresins, it causes an increase of leucocytes in the blood and stimulates phagocytosis. [37] Commiphora mukul has antiarthritic, antiinflammatory, [38][39][40] antiseptic, antibacterial and antifungal activity, [41][42][43] antidiabetic, [44] In a recent study, C. mukul and guggulsterone were found to be effective antioxidant. [45] Guggulu has been used since ancient times in the various Indian system of medicines.…”

Section: Maximum Of Them Have Madhura Vipakamentioning

confidence: 99%

A Case Study on Puyalas (Acute Dacryocystitis) Through Ayurveda

2022

IJBPAS

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Puyalasa, one among the Sandhigataroga can be correlates to dacryocystitis based on the symptomatology which includes swelling in inner canthus, which later undergoes suppuration causing thick purulent discharge. Dacryocystitis (Puyalas) is the inflammation of the lacrimal sac. Management of acute dacryocystitis differs based on the stage. In the present case report, a 50-year-old male patient suffered from this disease. He presented with the chief complaints of watering from Right eye for 6 and half months and mild swelling and pain over the lacrimal sac area in Right eye for 7 days. He was treated with Raktamokshana with jalokaavcharana, Triphala Guggulu and Triphaladi Netra Parisheka, along with Vimlapana in lacrimal sac area for 1 month. After 1 month of treatment, the patient got relief from all the complaints. In lacrimal syringing, there was mild obstruction or regurgitation found. On analysis of all the data, it can be concluded that Ayurvedic management with Raktamokshana with jalokaavcharana, Triphaladi Netra Parisheka and Triphala Guggulu along with Vimlapana in the lacrimal sac area offers effective result in the treatment of Puyalasa.

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In vitro Antibacterial Activity of n-Hexane Fraction of Methanolic Extract of Plumeria rubra L. (Apocynaceae) Stem Bark

Cited by 16 publications

References 22 publications

Interkingdom Responses to Bacterial Quorum Sensing Signals Regulate Frequency and Rate of Nodulation in Legume–Rhizobia Symbiosis

Interkingdom Responses to Bacterial Quorum Sensing Signals Regulate Frequency and Rate of Nodulation in Legume–Rhizobia Symbiosis

A comprehensive review on traditional uses, phytochemistry and pharmacological properties of Paeonia emodi Wall. ex Royle: current landscape and future perspectives

A Case Study on Puyalas (Acute Dacryocystitis) Through Ayurveda

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