In vitro anti influenza virus activity, antioxidant potential and total phenolic content of twelve Iranian medicinal plants

Moradi, Mohammad-Taghi; Karimi, Ali; Lorigooini, Zahra; POURGHEYSARI, Batoul; Alidadi, Somayeh

doi:10.12991/mpj.2017.10

Cited by 22 publications

(14 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“… Choi (2018) Papaver rhoeas L. Kaempferol-3-sophoroside, Kaempferol-3-neohesperidoside, Kaempferol-3-sambubioside, Kaempferol-3-glucoside, Quercetin-3-sophoroside, Luteolin, Chelianthifoline (Pollen) Display noncompetitive inhibition of H3N2 neuraminidase and reduce the severity of virally induced cytopathic effects Lee et al (2016) Peganum harmala L. Not specified (Seeds) Inhibit cytopathic effect of influenza virus Moradi et al (2017) Pimpinella anisum L. Not specified (Essential oil) Linalool (Essential oil) Linalool (Essential oil) Reduce visible cytopathic effects of influenza A/WS/33 virus activity by > 52.8%. Choi (2018) Portulaca oleracea L. Not specified (Aerial parts) Suppress the production of circulating H1N1 and H3N2 and inhibit the binding of virus to cells and decrease the viral load within 10 min to prevent viral infection Li et al (2019) Punica granatum L. Not specified (Seeds) Inhibit cytopathic effect of influenza virus Moradi et al (2017) Punica granatum L. Ellagic acid, Caffeic acid, Luteolin, and Punicalagin (Fruit juice) Suppress replication of influenza A virus and inhibit viral RNA replication and agglutination of chicken red blood cells by influenza virus Haidari et al (2009) Salvia fruticosa Mill. Not specified (Aerial parts-Essential oil) Both in influenza A/H1N1 and HRV14, replication cycle and progeny virus production were significantly decreased after the treatment with CAPeo (An essential oil combination based on three aromatic plants ( Thymbra capitata, Origanum dictamnus and Salvia fruticosa in extra-virgin olive oil) Tseliou et al (2019) Salvia officinalis L. Citronellol and Eugenol (Leaves, Essential oil) 1,8-Cineole and α-Thujone (Leaves) Inhibits the hemagglutinin activity, but not the Neuraminida...…”

Section: Resultsmentioning

confidence: 99%

Potential anti-influenza effective plants used in Turkish folk medicine: A review

Sargın

2021

Journal of Ethnopharmacology

View full text Add to dashboard Cite

Ethnopharmacological relevance Due to the outbreaks such as SARS, bird flu and swine flu, which we frequently encounter in our century, we need fast solutions with no side effects today more than ever. Due to having vast ethnomedical experience and the richest flora (34% endemic) of Europe and the Middle East, Turkey has a high potential for research on this topic. Plants that locals have been using for centuries for the prevention and treatment of influenza can offer effective alternatives to combat this problem. In this context, 224 herbal taxa belonging to 45 families were identified among the selected 81 studies conducted in the seven regions of Turkey. However, only 35 (15.6%) of them were found to be subjected to worldwide in vitro and in vivo research conducted on anti-influenza activity. Quercetin and chlorogenic acid, the effectiveness of which has been proven many times in this context, have been recorded as the most common (7.1%) active ingredients among the other 56 active substances identified. Aim of the study This study has been carried out to reveal the inventory of plant species that have been used in flu treatment for centuries in Turkish folk medicine, which could be used in the treatment of flu or flu-like pandemics, such as COVID 19, that humanity has been suffering with, and also compare them with experimental studies in the literature. Materials and methods The investigation was conducted in two stages on the subject above by using electronic databases, such as Web of Science, Scopus, ScienceDirect, ProQuest, Medline, Cochrane Library, EBSCO, HighWire Press, PubMed and Google Scholar. The results of both scans are presented in separate tables, together with their regional comparative analysis. Results Data obtained on taxa are presented in a table, including anti-influenza mechanism of actions and the active substances. Rosa canina (58.7%) and Mentha x piperita (22.2%) were identified as the most common plants used in Turkey. Also, Sambucus nigra (11.6%) , Olea europaea (9.3%), Eucalyptus spp., Melissa officinalis, and Origanum vulgare (7.0%) emerged as the most investigated taxa. Conclusion This is the first nationwide ethnomedical screening work conducted on flu treatment with plants in Turkey. Thirty-nine plants have been confirmed in the recent experimental anti-influenza research, which strongly shows that these plants are a rich pharmacological source. Also, with 189 (84.4%) taxa, detections that have not been investigated yet, they are an essential resource for both national and international pharmacological researchers in terms of new natural medicine searches. Considering that the production of antimalarial drugs...

show abstract

Section: Resultsmentioning

confidence: 99%

Potential anti-influenza effective plants used in Turkish folk medicine: A review

Sargın

2021

Journal of Ethnopharmacology

View full text Add to dashboard Cite

show abstract

“…The effects of C. orientalis M Bieber extract on serum oxidative status and alveolar bone loss in experimental periodontitis was studied in vivo and showed inhibitory effect on periodontal inflammation and alveolar bone loss by regulating total antioxidant (TAS)/oxidant (TOS) status and oxidative stress index levels in periodontal disease in rats when administered systemically (Hatipoglu et al, 2015). C. azarolus extract was active against herpes simplex virus-1 (HSV-1), and antiviral activity correlated with TPC (R = 0.773, p < 0.001) and free radical scavenging capacity (R = −0.684, p < 0.01) (Moradi et al, 2018). Hawthorn hyperoside (10, 50, 100 μmol/L) dose-dependently inhibited LPS-induced pro-…”

Section: Skin Protective and Other Health Effectsmentioning

confidence: 99%

Phytochemical composition and bioactivities of hawthorn (Crataegus spp.): review of recent research advances

Venskutonis¹

2018

JFB

View full text Add to dashboard Cite

Hawthorn (Crataegus spp.) is one of the most famous plants which has been used as natural medicine and nutraceutical. Its phytochemical composition, bioactive compounds and health benefits have been intensively studied and hawthorn preparations may be recognized as classical natural products for cardiovascular health. Polyphenolic compounds of different hawthorn anatomical parts as well as their extracts have been the focus of a majority of these studies, although various other classes of natural health promoting constituents have also been isolated, identified and characterized. Regardless, numerous published reports have particularly focused on the activity mechanisms which are very important for supporting various health benefits. This review summarizes the most recent studies on hawthorn, mainly published since 2015. Search of different databases indicates that approximately 200 publications, which are relevant to phytochemistry and health benefits of Crataegus spp., have appeared since then, most of them have not been included in the existing reviews.

show abstract

“…Hydroalcoholic extract exhibits anti-viral activity against herpes simplex virus-1 evaluated on vero cell line using MTT assay. IC 50 : 8.4 μg/mlMoradi et al (2018) Aqueous extract decreases neutrophil count and proteins leakage into bronchoalveolar lavage fluid. Dose: 200 mg/kgChniguir et al (2019) C2.40 Terminalia chebula Retz./Halala/Combretaceae/ Fruits…”

mentioning

confidence: 98%

Indian Medicinal Plants and Formulations and Their Potential Against COVID-19–Preclinical and Clinical Research

et al. 2021

View full text Add to dashboard Cite

The cases of COVID-19 are still increasing day-by-day worldwide, even after a year of its first occurrence in Wuhan city of China. The spreading of SARS-CoV-2 infection is very fast and different from other SARS-CoV infections possibly due to structural differences in S proteins. The patients with severe diseases may die due to acute respiratory distress syndrome (ARDS) caused by systemic inflammatory reactions due to the excessive release of pro-inflammatory cytokines and chemokines by the immune effector cells. In India too, it is spreading very rapidly, although the case fatality rate is below 1.50% (https://www.statista.com), which is markedly less than in other countries, despite the dense population and minimal health infrastructure in rural areas. This may be due to the routine use of many immunomodulator medicinal plants and traditional AYUSH formulations by the Indian people. This communication reviews the AYUSH recommended formulations and their ingredients, routinely used medicinal plants and formulations by Indian population as well as other promising Indian medicinal plants, which can be tested against COVID-19. Special emphasis is placed on Indian medicinal plants reported for antiviral, immunomodulatory and anti-allergic/anti-inflammatory activities and they are categorized for prioritization in research on the basis of earlier reports. The traditional AYUSH medicines currently under clinical trials against COVID-19 are also discussed as well as furtherance of pre-clinical and clinical testing of the potential traditional medicines against COVID-19 and SARS-CoV-2. The results of the clinical studies on AYUSH drugs will guide the policymakers from the AYUSH systems of medicines to maneuver their policies for public health, provide information to the global scientific community and could form a platform for collaborative studies at national and global levels. It is thereby suggested that promising AYUSH formulations and Indian medicinal plants must be investigated on a priority basis to solve the current crisis.

show abstract

In vitro anti influenza virus activity, antioxidant potential and total phenolic content of twelve Iranian medicinal plants

Cited by 22 publications

References 31 publications

Potential anti-influenza effective plants used in Turkish folk medicine: A review

Potential anti-influenza effective plants used in Turkish folk medicine: A review

Phytochemical composition and bioactivities of hawthorn (Crataegus spp.): review of recent research advances

Indian Medicinal Plants and Formulations and Their Potential Against COVID-19–Preclinical and Clinical Research

Contact Info

Product

Resources

About