In vitro anti-inflammatory and skin protective properties of extract comprising ceramides from de-oiled rice bran

Sahoo, Manas Ranjan; Varma, Sandeep R.; Patel, Neeraj K.; Sivaprakasam, Thiyagarajan O.; Mishra, Abheepsa; Muguli, Ganesh; Babu, Suresh K.; Babu, Uddagiri Venkanna; Paramesh, Rangesh; Jadhav, Atul N.

doi:10.1111/jfbc.12353

Cited by 2 publications

(1 citation statement)

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“…Compared with refined rice, rice bran contains more nutrients. It has high amounts of vitamins, minerals, and cellulose and can decrease cholesterol; furthermore, its phenol compounds can prevent atherosclerosis (Sahoo et al., 2017). Rice bran contains large amounts of biologically active substances, and its considerable polyphenols meant that rice bran is high in antioxidants (Srinivasan et al., 2007).…”

Section: Introductionmentioning

confidence: 99%

A clinical empirical study on the role of refined rice bran in the prevention and improvement of metabolic syndrome

Lin

Chao

et al. 2020

J. Food Biochem.

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Rice bran contains lipolytic enzymes with extremely high activity that facilitate the hydrolysis of triglycerides into glycerol and fatty acids. This also causes rice bran to easily deteriorate, limiting its use, and they are not popular in the market. Researchers look forward to seeing the refined rice brans work well for metabolic syndrome. This study used gas cooling by liquid nitrogen and an instant sterilization system operated at high temperature to stabilize and refine the rice bran. The refined rice bran was compared using in vitro tests with three other types of rice bran that had not been specially treated. The refined rice bran was discovered to have superior solubility, fast absorption, and excellent oxidation resistance compared with the other three rice bran samples. In a human subject test, significant improvements in waistline, systolic pressure, diastolic pressure, fasting plasma glucose, glycated hemoglobin, and triglyceride level were discovered after participants ingested refined rice bran for 8 weeks. This indicated that consuming refined rice bran can reduce the waistline, control blood pressure and blood glucose, and inhibit fate formation. The items for which significance was obtained are also the indicators of metabolic syndrome, as stipulated by the World Health Organization. Therefore, according to the results of the human subject test, ingesting refined rice bran can improve the metabolic syndrome. Practical applications This refinement improved the in vivo absorption and stabilized the properties of the rice bran for better preservation. In this study, excellent results were obtained using the refined rice bran in both in vitro tests and a human subject test. Refined rice bran thus has potential for mass production and used as a health supplement. It can alleviate the symptoms of metabolic syndrome and reduce the incidence of cardiovascular diseases.

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Section: Introductionmentioning

confidence: 99%