In Vitro Anti Inflammatory Activity of Tecomaria Capensis (Thunb) Leaves of Different Extracts.

Abstract

Tecomaria Capensis (family: Bignoniaceae) also known as Cape-honeysuckle. The present work aims at evaluating the anti inflammatory activity of Tecomaria Capensis by HRBC membrane stabilization. The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti inflammatory activity. The anti inflammatory activity of the crude Ethyl Acetate extract (EAE), Ethanol extract (EE), Water extract (WE) of leaves part of Tecomaria Capensis were compared to that of the standard drug diclofenac. The percentage protection of lysis for Standard Diclofenac100 µg is 27.203%,Standard Diclofenac 200 µg is 38.972%,Ethyl acetate extract 100µg is 21.985%, Ethyl acetate extract 200µgis 31.765%, Ethanolic extract 100µg is 33.221%, Ethanolic extract 200µgis 41.447%, Aqueous extract 100 µg is 13.25%, Aqueous extract 200µgis 21.112%. The ethanolic extract of Tecomaria capensishas significant anti inflammatory activity in comparison to aqueous extract and ethyl acetate extract of the same plant and with standard drug diclofenac.